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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 19

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Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
Singh K, Coburn LA, Asim M, Barry DP, Allaman MM, Shi C, Washington MK, Luis PB, Schneider C, Delgado AG, Piazuelo MB, Cleveland JL, Gobert AP, Wilson KT
(2018) Cancer Res 78: 4303-4315
MeSH Terms: Animals, Azoxymethane, Carcinogenesis, Colitis, Ulcerative, Colon, Colonic Neoplasms, Cytokines, Dextran Sulfate, Inflammation, Macrophage Activation, Macrophages, Male, Mice, Ornithine Decarboxylase, Transcription, Genetic, Up-Regulation
Added June 15, 2018
0 Communities
2 Members
0 Resources
16 MeSH Terms
Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications.
Hardbower DM, Asim M, Luis PB, Singh K, Barry DP, Yang C, Steeves MA, Cleveland JL, Schneider C, Piazuelo MB, Gobert AP, Wilson KT
(2017) Proc Natl Acad Sci U S A 114: E751-E760
MeSH Terms: Animals, Cell Line, Citrobacter rodentium, Colitis, Colon, Cytokines, Enterobacteriaceae Infections, Gastric Mucosa, Gastritis, Helicobacter Infections, Helicobacter pylori, Histones, Humans, Macrophage Activation, Macrophages, Male, Mice, NLR Family, Pyrin Domain-Containing 3 Protein, Ornithine Decarboxylase, Putrescine
Added January 19, 2017
0 Communities
1 Members
0 Resources
20 MeSH Terms
Methods to evaluate alterations in polyamine metabolism caused by Helicobacter pylori infection.
Gobert AP, Chaturvedi R, Wilson KT
(2011) Methods Mol Biol 720: 409-25
MeSH Terms: Acetyltransferases, Animals, Apoptosis, Arginase, Arsenicals, Biochemistry, Cells, Cultured, Enzyme Assays, Helicobacter Infections, Helicobacter pylori, Humans, Immunoblotting, Luciferases, Macrophages, Mice, Nitrogen Dioxide, Ornithine Decarboxylase, Oxidoreductases Acting on CH-NH Group Donors, Polyamines, Promoter Regions, Genetic, RNA, Messenger, Transfection
Added March 5, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production.
Chaturvedi R, Asim M, Hoge S, Lewis ND, Singh K, Barry DP, de Sablet T, Piazuelo MB, Sarvaria AR, Cheng Y, Closs EI, Casero RA, Gobert AP, Wilson KT
(2010) Gastroenterology 139: 1686-98, 1698.e1-6
MeSH Terms: Animals, Arginine, Cationic Amino Acid Transporter 2, Cells, Cultured, Disease Models, Animal, Gastric Mucosa, Gastritis, Gene Expression Regulation, Helicobacter Infections, Helicobacter pylori, Humans, Immunity, Cellular, Macrophages, Mice, Mice, Inbred C57BL, Nitric Oxide, Nitric Oxide Synthase Type II, Ornithine Decarboxylase, Polyamines, RNA, Reverse Transcriptase Polymerase Chain Reaction, Spermine
Added March 5, 2014
0 Communities
3 Members
0 Resources
22 MeSH Terms
Helicobacter pylori induces ERK-dependent formation of a phospho-c-Fos c-Jun activator protein-1 complex that causes apoptosis in macrophages.
Asim M, Chaturvedi R, Hoge S, Lewis ND, Singh K, Barry DP, Algood HS, de Sablet T, Gobert AP, Wilson KT
(2010) J Biol Chem 285: 20343-57
MeSH Terms: Animals, Anthracenes, Apoptosis, Cell Line, Cell Nucleus, Cell Survival, Extracellular Signal-Regulated MAP Kinases, Flavonoids, Fluorescence Resonance Energy Transfer, Helicobacter Infections, Helicobacter pylori, Host-Pathogen Interactions, Imidazoles, Immunoblotting, Macromolecular Substances, Macrophages, Mice, Mice, Inbred C57BL, Ornithine Decarboxylase, Phosphorylation, Protein Binding, Proto-Oncogene Proteins c-fos, Proto-Oncogene Proteins c-jun, Pyridines, Reverse Transcriptase Polymerase Chain Reaction, Transcription Factor AP-1
Added March 5, 2014
0 Communities
4 Members
0 Resources
26 MeSH Terms
ZNF9 activation of IRES-mediated translation of the human ODC mRNA is decreased in myotonic dystrophy type 2.
Sammons MA, Antons AK, Bendjennat M, Udd B, Krahe R, Link AJ
(2010) PLoS One 5: e9301
MeSH Terms: 5' Untranslated Regions, Binding Sites, Blotting, Western, Cell Line, Cells, Cultured, HeLa Cells, Humans, Myoblasts, Myotonic Dystrophy, Ornithine Decarboxylase, Protein Binding, Protein Biosynthesis, RNA Caps, RNA Interference, RNA, Messenger, RNA-Binding Proteins, Reverse Transcriptase Polymerase Chain Reaction, Ribosomes
Added April 18, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
Identification of breast cancer peptide epitopes presented by HLA-A*0201.
Hawkins OE, Vangundy RS, Eckerd AM, Bardet W, Buchli R, Weidanz JA, Hildebrand WH
(2008) J Proteome Res 7: 1445-57
MeSH Terms: Amino Acid Sequence, Breast Neoplasms, CD8-Positive T-Lymphocytes, Cell Line, Tumor, Chromatography, High Pressure Liquid, Cyclin-Dependent Kinase 2, Cytoskeletal Proteins, Epitopes, T-Lymphocyte, Exoribonucleases, Female, HLA-A Antigens, HLA-A2 Antigen, Humans, Interferon-gamma, Intramolecular Oxidoreductases, Leukocytes, Mononuclear, Macrophage Migration-Inhibitory Factors, Mass Spectrometry, Nuclear Proteins, Ornithine Decarboxylase
Added May 31, 2013
0 Communities
1 Members
0 Resources
20 MeSH Terms
The myotonic dystrophy type 2 protein ZNF9 is part of an ITAF complex that promotes cap-independent translation.
Gerbasi VR, Link AJ
(2007) Mol Cell Proteomics 6: 1049-58
MeSH Terms: Cell Line, Centrifugation, Density Gradient, Humans, Multiprotein Complexes, Ornithine Decarboxylase, Protein Binding, Protein Biosynthesis, Protein Transport, Proteomics, RNA Caps, RNA-Binding Proteins, Regulatory Sequences, Ribonucleic Acid, Ribonucleoproteins, Ribosomes
Added April 18, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
Helicobacter pylori-induced macrophage apoptosis requires activation of ornithine decarboxylase by c-Myc.
Cheng Y, Chaturvedi R, Asim M, Bussière FI, Scholz A, Xu H, Casero RA, Wilson KT
(2005) J Biol Chem 280: 22492-6
MeSH Terms: Active Transport, Cell Nucleus, Animals, Apoptosis, Cell Line, Enzyme Activation, Genes, Dominant, Helicobacter pylori, Immunoblotting, Luciferases, Macrophages, Mice, Ornithine Decarboxylase, Polyamines, Promoter Regions, Genetic, Protein Binding, Protein Transport, Proto-Oncogene Proteins c-myc, RNA, Messenger, RNA, Small Interfering, Reverse Transcriptase Polymerase Chain Reaction, Time Factors, Transcriptional Activation, Transfection
Added March 5, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Protective role of arginase in a mouse model of colitis.
Gobert AP, Cheng Y, Akhtar M, Mersey BD, Blumberg DR, Cross RK, Chaturvedi R, Drachenberg CB, Boucher JL, Hacker A, Casero RA, Wilson KT
(2004) J Immunol 173: 2109-17
MeSH Terms: Animals, Arginase, Arginine, Boronic Acids, Citrobacter rodentium, Colitis, Eflornithine, Enterobacteriaceae Infections, Enzyme Induction, Enzyme Inhibitors, Mice, Mice, Inbred C57BL, Mice, Knockout, Nitric Oxide Synthase, Nitric Oxide Synthase Type II, Ornithine, Ornithine Decarboxylase, Polyamines
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms