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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 25

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The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.
Shen C, Nayak A, Neitzel LR, Adams AA, Silver-Isenstadt M, Sawyer LM, Benchabane H, Wang H, Bunnag N, Li B, Wynn DT, Yang F, Garcia-Contreras M, Williams CH, Dakshanamurthy S, Hong CC, Ayad NG, Capobianco AJ, Ahmed Y, Lee E, Robbins DJ
(2021) Nat Commun 12: 5263
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Casein Kinase Ialpha, Drosophila Proteins, Drosophila melanogaster, Embryo, Nonmammalian, Evolution, Molecular, HEK293 Cells, Humans, Immunologic Factors, Lenalidomide, Mice, Organoids, Peptide Hydrolases, Ubiquitin-Protein Ligases, Ubiquitination, Wnt Signaling Pathway, Zebrafish, Zebrafish Proteins
Added September 11, 2021
0 Communities
1 Members
0 Resources
19 MeSH Terms
Cell differentiation is disrupted by MYO5B loss through Wnt/Notch imbalance.
Kaji I, Roland JT, Rathan-Kumar S, Engevik AC, Burman A, Goldstein AE, Watanabe M, Goldenring JR
(2021) JCI Insight 6:
MeSH Terms: Animals, Cell Differentiation, Cells, Cultured, Dibenzazepines, Disease Models, Animal, Enterocytes, Humans, Intestinal Mucosa, Jejunum, Lysophospholipids, Malabsorption Syndromes, Mice, Mice, Knockout, Microvilli, Mucolipidoses, Myosin Type V, Organoids, Primary Cell Culture, Receptors, Notch, Stem Cells, Wnt Signaling Pathway
Added August 16, 2021
1 Communities
0 Members
0 Resources
21 MeSH Terms
Immunofluorescent staining of cancer spheroids and fine-needle aspiration-derived organoids.
Bergdorf KN, Phifer CJ, Bechard ME, Lee MA, McDonald OG, Lee E, Weiss VL
(2021) STAR Protoc 2: 100578
MeSH Terms: Biopsy, Fine-Needle, Cells, Cultured, Fluorescent Antibody Technique, Humans, Organoids, Spheroids, Cellular, Tumor Cells, Cultured
Added May 10, 2022
0 Communities
1 Members
0 Resources
MeSH Terms
Obtaining patient-derived cancer organoid cultures via fine-needle aspiration.
Phifer CJ, Bergdorf KN, Bechard ME, Vilgelm A, Baregamian N, McDonald OG, Lee E, Weiss VL
(2021) STAR Protoc 2: 100220
MeSH Terms: Biopsy, Fine-Needle, Female, Humans, Male, Neoplasms, Organoids, Tumor Cells, Cultured
Added February 18, 2021
0 Communities
1 Members
0 Resources
7 MeSH Terms
High-throughput drug screening of fine-needle aspiration-derived cancer organoids.
Bergdorf K, Phifer C, Bharti V, Westover D, Bauer J, Vilgelm A, Lee E, Weiss V
(2020) STAR Protoc 1: 100212
MeSH Terms: Biopsy, Fine-Needle, Cell Culture Techniques, Drug Evaluation, Preclinical, Early Detection of Cancer, High-Throughput Screening Assays, Humans, Neoplasms, Organoids
Added February 18, 2021
0 Communities
1 Members
0 Resources
8 MeSH Terms
Dicarbonyl Electrophiles Mediate Inflammation-Induced Gastrointestinal Carcinogenesis.
Gobert AP, Boutaud O, Asim M, Zagol-Ikapitte IA, Delgado AG, Latour YL, Finley JL, Singh K, Verriere TG, Allaman MM, Barry DP, McNamara KM, Sierra JC, Amarnath V, Tantawy MN, Bimczok D, Piazuelo MB, Washington MK, Zhao S, Coburn LA, Wilson KT
(2021) Gastroenterology 160: 1256-1268.e9
MeSH Terms: Animals, Benzylamines, Cell Nucleus, Cell Transformation, Neoplastic, Colitis-Associated Neoplasms, Disease Models, Animal, Epithelial Cells, Gastric Mucosa, Gastritis, Gerbillinae, Helicobacter Infections, Helicobacter pylori, Humans, Lipids, Metaplasia, Mice, Mice, Transgenic, Organoids, Precancerous Conditions, Stomach Neoplasms
Added March 17, 2021
0 Communities
1 Members
0 Resources
20 MeSH Terms
Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling.
Sierra JC, Piazuelo MB, Luis PB, Barry DP, Allaman MM, Asim M, Sebrell TA, Finley JL, Rose KL, Hill S, Holshouser SL, Casero RA, Cleveland JL, Woster PM, Schey KL, Bimczok D, Schneider C, Gobert AP, Wilson KT
(2020) Oncogene 39: 4465-4474
MeSH Terms: Adenocarcinoma, Animals, Cell Transformation, Neoplastic, DNA Damage, Gastritis, Helicobacter Infections, Helicobacter pylori, Mice, Mice, Inbred C57BL, Mice, Knockout, Organoids, Oxidoreductases Acting on CH-NH Group Donors, Proteome, RNA, Messenger, Signal Transduction, Spermidine, Spermine, Stomach Neoplasms, beta Catenin
Added May 1, 2020
0 Communities
1 Members
0 Resources
19 MeSH Terms
infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease.
Mileto SJ, Jardé T, Childress KO, Jensen JL, Rogers AP, Kerr G, Hutton ML, Sheedlo MJ, Bloch SC, Shupe JA, Horvay K, Flores T, Engel R, Wilkins S, McMurrick PJ, Lacy DB, Abud HE, Lyras D
(2020) Proc Natl Acad Sci U S A 117: 8064-8073
MeSH Terms: Animals, Bacterial Proteins, Bacterial Toxins, Cells, Cultured, Clostridioides difficile, Clostridium Infections, Colon, Disease Models, Animal, Female, Frizzled Receptors, Humans, Intestinal Mucosa, Mice, Organoids, Primary Cell Culture, Recombinant Proteins, Stem Cells
Added March 24, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
Uncovering cell biology in the third dimension.
Robertson GL, Romero-Morales AI, Lippmann ES, Gama V
(2020) Mol Biol Cell 31: 319-323
MeSH Terms: Brain, Cell Biology, Humans, Mitochondria, Neovascularization, Physiologic, Neurons, Organoids
Added August 24, 2020
0 Communities
1 Members
0 Resources
7 MeSH Terms
Modulation of sulfur assimilation metabolic toxicity overcomes anemia and hemochromatosis in mice.
Hale AT, Brown RE, Luka Z, Hudson BH, Matta P, Williams CS, York JD
(2020) Adv Biol Regul 76: 100694
MeSH Terms: Anemia, Iron-Deficiency, Animals, Basic Helix-Loop-Helix Transcription Factors, Diet, Disease Models, Animal, Female, Gene Expression Regulation, Hemochromatosis, Hemochromatosis Protein, Homeostasis, Homozygote, Humans, Intestinal Mucosa, Iron, Liver, Male, Methionine, Mice, Mice, Knockout, Mutation, Nucleotidases, Organoids, Signal Transduction, Sulfur
Added March 30, 2020
0 Communities
2 Members
0 Resources
24 MeSH Terms