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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 128

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Targeted Imaging of VCAM-1 mRNA in a Mouse Model of Laser-Induced Choroidal Neovascularization Using Antisense Hairpin-DNA-Functionalized Gold-Nanoparticles.
Uddin MI, Kilburn TC, Yang R, McCollum GW, Wright DW, Penn JS
(2018) Mol Pharm 15: 5514-5520
MeSH Terms: Animals, Biomarkers, Choroid, Choroidal Neovascularization, Disease Models, Animal, Fluorescent Dyes, Gold, Humans, Intravital Microscopy, Lasers, Male, Metal Nanoparticles, Mice, Mice, Inbred C57BL, Molecular Imaging, Molecular Probes, Oligodeoxyribonucleotides, Antisense, Optical Imaging, RNA, Messenger, Vascular Cell Adhesion Molecule-1, Wet Macular Degeneration
Added April 10, 2019
0 Communities
2 Members
0 Resources
21 MeSH Terms
Human DNA polymerase η accommodates RNA for strand extension.
Su Y, Egli M, Guengerich FP
(2017) J Biol Chem 292: 18044-18051
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Base Pair Mismatch, DNA Primers, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Electrophoretic Mobility Shift Assay, Humans, Kinetics, Nucleic Acid Heteroduplexes, Nucleic Acid Hybridization, Oligodeoxyribonucleotides, Oligoribonucleotides, Pyrimidine Dimers, RNA, Recombinant Proteins, Reverse Transcription, Substrate Specificity, Transcription Elongation, Genetic
Added March 14, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
Polymerase Bypass of N(6)-Deoxyadenosine Adducts Derived from Epoxide Metabolites of 1,3-Butadiene.
Kotapati S, Wickramaratne S, Esades A, Boldry EJ, Quirk Dorr D, Pence MG, Guengerich FP, Tretyakova NY
(2015) Chem Res Toxicol 28: 1496-507
MeSH Terms: Butadienes, Chromatography, High Pressure Liquid, DNA, DNA Adducts, DNA Primers, DNA Replication, DNA-Directed DNA Polymerase, Deoxyadenosines, Epoxy Compounds, Humans, Kinetics, Oligodeoxyribonucleotides, Spectrometry, Mass, Electrospray Ionization
Added March 14, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
Synthesis of G-N2-(CH2)3-N2-G Trimethylene DNA Interstrand Cross-Links.
Gruppi F, Johnson Salyard TL, Rizzo CJ
(2014) Curr Protoc Nucleic Acid Chem 56: 5.14.1-15
MeSH Terms: Cross-Linking Reagents, Oligodeoxyribonucleotides
Added January 7, 2016
0 Communities
1 Members
0 Resources
2 MeSH Terms
Major groove orientation of the (2S)-N(6)-(2-hydroxy-3-buten-1-yl)-2'-deoxyadenosine DNA adduct induced by 1,2-epoxy-3-butene.
Kowal EA, Wickramaratne S, Kotapati S, Turo M, Tretyakova N, Stone MP
(2014) Chem Res Toxicol 27: 1675-86
MeSH Terms: Alkylation, Butadienes, DNA, DNA Adducts, Deoxyadenosines, Epoxy Compounds, Humans, Molecular Dynamics Simulation, Nuclear Magnetic Resonance, Biomolecular, Nucleic Acid Conformation, Nucleic Acid Denaturation, Oligodeoxyribonucleotides, Stereoisomerism, Transition Temperature, ras Proteins
Added January 20, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Base-displaced intercalation of the 2-amino-3-methylimidazo[4,5-f]quinolone N2-dG adduct in the NarI DNA recognition sequence.
Stavros KM, Hawkins EK, Rizzo CJ, Stone MP
(2014) Nucleic Acids Res 42: 3450-63
MeSH Terms: Aminoquinolines, Base Sequence, Benzimidazoles, DNA, DNA Adducts, Deoxyribonucleases, Type II Site-Specific, Models, Molecular, Nuclear Magnetic Resonance, Biomolecular, Nucleic Acid Conformation, Oligodeoxyribonucleotides, Protons
Added March 10, 2014
0 Communities
2 Members
0 Resources
11 MeSH Terms
Site-specific stabilization of DNA by a tethered major groove amine, 7-aminomethyl-7-deaza-2'-deoxyguanosine.
Szulik MW, Voehler MW, Ganguly M, Gold B, Stone MP
(2013) Biochemistry 52: 7659-68
MeSH Terms: DNA, Kinetics, Models, Molecular, Molecular Dynamics Simulation, Nuclear Magnetic Resonance, Biomolecular, Nucleic Acid Conformation, Nucleic Acid Denaturation, Nucleoside Q, Nucleotide Motifs, Oligodeoxyribonucleotides, Thermodynamics
Added March 7, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
1,N2-Etheno-2'-deoxyguanosine adopts the syn conformation about the glycosyl bond when mismatched with deoxyadenosine.
Shanmugam G, Kozekov ID, Guengerich FP, Rizzo CJ, Stone MP
(2011) Chem Res Toxicol 24: 1071-9
MeSH Terms: Base Pair Mismatch, DNA Polymerase I, DNA Polymerase II, DNA Polymerase beta, Deoxyadenosines, Escherichia coli, Hydrogen Bonding, Hydrogen-Ion Concentration, Magnetic Resonance Spectroscopy, Oligodeoxyribonucleotides, Protons, Sulfolobus solfataricus, Transition Temperature
Added March 7, 2014
0 Communities
3 Members
0 Resources
13 MeSH Terms
γ-Hydroxy-1,N2-propano-2'-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage.
Huang H, Wang H, Voehler MW, Kozekova A, Rizzo CJ, McCullough AK, Lloyd RS, Stone MP
(2011) Chem Res Toxicol 24: 1123-33
MeSH Terms: Acrolein, Amines, Amino Acid Sequence, DNA Adducts, Deoxyguanosine, Hydrogen Bonding, Imines, Magnetic Resonance Spectroscopy, Molecular Dynamics Simulation, Oligodeoxyribonucleotides, Peptides, Transition Temperature
Added March 7, 2014
0 Communities
2 Members
0 Resources
12 MeSH Terms
Drosophila MMP2 regulates the matrix molecule faulty attraction (Frac) to promote motor axon targeting in Drosophila.
Miller CM, Liu N, Page-McCaw A, Broihier HT
(2011) J Neurosci 31: 5335-47
MeSH Terms: Age Factors, Animals, Animals, Genetically Modified, Axons, Bone Morphogenetic Proteins, Calcium-Binding Proteins, Drosophila, Drosophila Proteins, Embryo, Nonmammalian, Extracellular Matrix Proteins, Gene Expression Regulation, Developmental, Green Fluorescent Proteins, Helix-Loop-Helix Motifs, Humans, Lim Kinases, Matrix Metalloproteinase 2, Microfilament Proteins, Models, Biological, Motor Neurons, Mutation, Neuroglia, Oligodeoxyribonucleotides, Antisense, RNA, Signal Transduction, Two-Hybrid System Techniques
Added March 5, 2014
0 Communities
1 Members
0 Resources
25 MeSH Terms