Effects of Twelve Germline Missense Variations on DNA Lesion and G-Quadruplex Bypass Activities of Human DNA Polymerase REV1.
Yeom M, Kim IH, Kim JK, Kang K, Eoff RL, Guengerich FP, Choi JY
(2016) Chem Res Toxicol 29
: 367-79MeSH Terms: DNA, DNA Adducts, DNA Damage, G-Quadruplexes, Germ-Line Mutation, Humans, Models, Molecular, Mutation, Missense, Nuclear Proteins, NucleotidyltransferasesAdded March 14, 2018
10 MeSH Terms
Pancreas-specific Cre driver lines and considerations for their prudent use.
Magnuson MA, Osipovich AB
(2013) Cell Metab 18
: 9-20MeSH Terms: Animals, DNA Nucleotidyltransferases, Extracellular Matrix Proteins, Integrases, Mice, Mice, Knockout, Mice, Transgenic, Models, Animal, Pancreas, Pancreatic Hormones, Protein-Lysine 6-Oxidase, Rats, Rats, Transgenic, Recombination, Genetic, TransgenesAdded August 1, 2013
15 MeSH Terms
Basis of miscoding of the DNA adduct N2,3-ethenoguanine by human Y-family DNA polymerases.
Zhao L, Pence MG, Christov PP, Wawrzak Z, Choi JY, Rizzo CJ, Egli M, Guengerich FP
(2012) J Biol Chem 287
: 35516-35526MeSH Terms: Cell-Free System, DNA Adducts, DNA Polymerase beta, DNA-Directed DNA Polymerase, Guanine, Humans, Nuclear Proteins, NucleotidyltransferasesAdded March 7, 2014
8 MeSH Terms
Conditional control of gene function by an invertible gene trap in zebrafish.
Ni TT, Lu J, Zhu M, Maddison LA, Boyd KL, Huskey L, Ju B, Hesselson D, Zhong TP, Page-McCaw PS, Stainier DY, Chen W
(2012) Proc Natl Acad Sci U S A 109
: 15389-94MeSH Terms: Alleles, Animals, DNA Nucleotidyltransferases, DNA Transposable Elements, Hepatocytes, Integrases, Liver, Mitochondria, Models, Genetic, Mutagenesis, Mutagens, Mutation, Phenotype, Polymerase Chain Reaction, RNA Helicases, Recombination, Genetic, ZebrafishAdded January 7, 2014
17 MeSH Terms
Replication of the 2,6-diamino-4-hydroxy-N(5)-(methyl)-formamidopyrimidine (MeFapy-dGuo) adduct by eukaryotic DNA polymerases.
Christov PP, Yamanaka K, Choi JY, Takata K, Wood RD, Guengerich FP, Lloyd RS, Rizzo CJ
(2012) Chem Res Toxicol 25
: 1652-61MeSH Terms: Chromatography, High Pressure Liquid, DNA, DNA Adducts, DNA Replication, DNA-Directed DNA Polymerase, Kinetics, Nuclear Proteins, Nucleotidyltransferases, Oligonucleotides, Sequence Analysis, DNA, Spectrometry, Mass, Electrospray IonizationAdded March 7, 2014
11 MeSH Terms
Bid protects the mouse hematopoietic system following hydroxyurea-induced replicative stress.
Liu Y, Aiello A, Zinkel SS
(2012) Cell Death Differ 19
: 1602-12MeSH Terms: Animals, Antigens, Ly, Antineoplastic Agents, Apoptosis, Ataxia Telangiectasia Mutated Proteins, BH3 Interacting Domain Death Agonist Protein, Cell Cycle Proteins, DNA Repair, Hematopoietic Stem Cell Transplantation, Hematopoietic Stem Cells, Hydroxyurea, Membrane Proteins, Methylcellulose, Mice, Mice, Inbred C57BL, Mice, Knockout, Myeloid Progenitor Cells, Nucleotidyltransferases, Oxidative Stress, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins c-kitAdded December 5, 2013
21 MeSH Terms
Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background.
Birling MC, Dierich A, Jacquot S, Hérault Y, Pavlovic G
(2012) Genesis 50
: 482-9MeSH Terms: Animals, Bacterial Proteins, DNA Nucleotidyltransferases, Founder Effect, Gene Targeting, Genetic Engineering, Genotype, Green Fluorescent Proteins, Homologous Recombination, Integrases, Luminescent Proteins, Mice, Mice, Inbred C57BL, Mice, Transgenic, Proteins, RNA, Untranslated, Sequence DeletionAdded March 20, 2013
17 MeSH Terms
Translesion synthesis across abasic lesions by human B-family and Y-family DNA polymerases α, δ, η, ι, κ, and REV1.
Choi JY, Lim S, Kim EJ, Jo A, Guengerich FP
(2010) J Mol Biol 404
: 34-44MeSH Terms: DNA, DNA Damage, DNA Polymerase I, DNA Polymerase III, DNA Repair, DNA Replication, DNA-Directed DNA Polymerase, Humans, Kinetics, Nuclear Proteins, Nucleotidyltransferases, Oligonucleotides, Proliferating Cell Nuclear AntigenAdded March 26, 2014
13 MeSH Terms
An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase.
Kranz A, Fu J, Duerschke K, Weidlich S, Naumann R, Stewart AF, Anastassiadis K
(2010) Genesis 48
: 512-20MeSH Terms: Animals, Base Sequence, Binding Sites, Cell Line, Cells, Cultured, DNA Nucleotidyltransferases, Embryo, Mammalian, Embryonic Stem Cells, Female, Fibroblasts, Gene Expression Regulation, Developmental, Gene Knockout Techniques, Green Fluorescent Proteins, Isoenzymes, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Plasmids, Recombination, Genetic, TransfectionAdded March 20, 2013
21 MeSH Terms
Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice.
Anastassiadis K, Fu J, Patsch C, Hu S, Weidlich S, Duerschke K, Buchholz F, Edenhofer F, Stewart AF
(2009) Dis Model Mech 2
: 508-15MeSH Terms: Animals, Base Sequence, Cell Line, DNA Nucleotidyltransferases, Embryonic Stem Cells, Escherichia coli, Escherichia coli Proteins, Gene Targeting, Genes, Reporter, Integrases, Ligands, Mice, Mifepristone, Molecular Sequence Data, Plasmids, Progesterone, Prokaryotic Cells, Proteins, RNA, Untranslated, Recombinant Fusion Proteins, Recombinases, Recombination, Genetic, Reproducibility of ResultsAdded June 25, 2010
23 MeSH Terms