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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 24

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Effects of Twelve Germline Missense Variations on DNA Lesion and G-Quadruplex Bypass Activities of Human DNA Polymerase REV1.
Yeom M, Kim IH, Kim JK, Kang K, Eoff RL, Guengerich FP, Choi JY
(2016) Chem Res Toxicol 29: 367-79
MeSH Terms: DNA, DNA Adducts, DNA Damage, G-Quadruplexes, Germ-Line Mutation, Humans, Models, Molecular, Mutation, Missense, Nuclear Proteins, Nucleotidyltransferases
Added March 14, 2018
0 Communities
1 Members
0 Resources
10 MeSH Terms
Pancreas-specific Cre driver lines and considerations for their prudent use.
Magnuson MA, Osipovich AB
(2013) Cell Metab 18: 9-20
MeSH Terms: Animals, DNA Nucleotidyltransferases, Extracellular Matrix Proteins, Integrases, Mice, Mice, Knockout, Mice, Transgenic, Models, Animal, Pancreas, Pancreatic Hormones, Protein-Lysine 6-Oxidase, Rats, Rats, Transgenic, Recombination, Genetic, Transgenes
Added August 1, 2013
2 Communities
2 Members
0 Resources
15 MeSH Terms
Basis of miscoding of the DNA adduct N2,3-ethenoguanine by human Y-family DNA polymerases.
Zhao L, Pence MG, Christov PP, Wawrzak Z, Choi JY, Rizzo CJ, Egli M, Guengerich FP
(2012) J Biol Chem 287: 35516-35526
MeSH Terms: Cell-Free System, DNA Adducts, DNA Polymerase beta, DNA-Directed DNA Polymerase, Guanine, Humans, Nuclear Proteins, Nucleotidyltransferases
Added March 7, 2014
0 Communities
3 Members
0 Resources
8 MeSH Terms
Conditional control of gene function by an invertible gene trap in zebrafish.
Ni TT, Lu J, Zhu M, Maddison LA, Boyd KL, Huskey L, Ju B, Hesselson D, Zhong TP, Page-McCaw PS, Stainier DY, Chen W
(2012) Proc Natl Acad Sci U S A 109: 15389-94
MeSH Terms: Alleles, Animals, DNA Nucleotidyltransferases, DNA Transposable Elements, Hepatocytes, Integrases, Liver, Mitochondria, Models, Genetic, Mutagenesis, Mutagens, Mutation, Phenotype, Polymerase Chain Reaction, RNA Helicases, Recombination, Genetic, Zebrafish
Added January 7, 2014
1 Communities
3 Members
0 Resources
17 MeSH Terms
Replication of the 2,6-diamino-4-hydroxy-N(5)-(methyl)-formamidopyrimidine (MeFapy-dGuo) adduct by eukaryotic DNA polymerases.
Christov PP, Yamanaka K, Choi JY, Takata K, Wood RD, Guengerich FP, Lloyd RS, Rizzo CJ
(2012) Chem Res Toxicol 25: 1652-61
MeSH Terms: Chromatography, High Pressure Liquid, DNA, DNA Adducts, DNA Replication, DNA-Directed DNA Polymerase, Kinetics, Nuclear Proteins, Nucleotidyltransferases, Oligonucleotides, Sequence Analysis, DNA, Spectrometry, Mass, Electrospray Ionization
Added March 7, 2014
0 Communities
2 Members
0 Resources
11 MeSH Terms
Bid protects the mouse hematopoietic system following hydroxyurea-induced replicative stress.
Liu Y, Aiello A, Zinkel SS
(2012) Cell Death Differ 19: 1602-12
MeSH Terms: Animals, Antigens, Ly, Antineoplastic Agents, Apoptosis, Ataxia Telangiectasia Mutated Proteins, BH3 Interacting Domain Death Agonist Protein, Cell Cycle Proteins, DNA Repair, Hematopoietic Stem Cell Transplantation, Hematopoietic Stem Cells, Hydroxyurea, Membrane Proteins, Methylcellulose, Mice, Mice, Inbred C57BL, Mice, Knockout, Myeloid Progenitor Cells, Nucleotidyltransferases, Oxidative Stress, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins c-kit
Added December 5, 2013
1 Communities
1 Members
0 Resources
21 MeSH Terms
Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background.
Birling MC, Dierich A, Jacquot S, Hérault Y, Pavlovic G
(2012) Genesis 50: 482-9
MeSH Terms: Animals, Bacterial Proteins, DNA Nucleotidyltransferases, Founder Effect, Gene Targeting, Genetic Engineering, Genotype, Green Fluorescent Proteins, Homologous Recombination, Integrases, Luminescent Proteins, Mice, Mice, Inbred C57BL, Mice, Transgenic, Proteins, RNA, Untranslated, Sequence Deletion
Added March 20, 2013
1 Communities
0 Members
0 Resources
17 MeSH Terms
Translesion synthesis across abasic lesions by human B-family and Y-family DNA polymerases α, δ, η, ι, κ, and REV1.
Choi JY, Lim S, Kim EJ, Jo A, Guengerich FP
(2010) J Mol Biol 404: 34-44
MeSH Terms: DNA, DNA Damage, DNA Polymerase I, DNA Polymerase III, DNA Repair, DNA Replication, DNA-Directed DNA Polymerase, Humans, Kinetics, Nuclear Proteins, Nucleotidyltransferases, Oligonucleotides, Proliferating Cell Nuclear Antigen
Added March 26, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase.
Kranz A, Fu J, Duerschke K, Weidlich S, Naumann R, Stewart AF, Anastassiadis K
(2010) Genesis 48: 512-20
MeSH Terms: Animals, Base Sequence, Binding Sites, Cell Line, Cells, Cultured, DNA Nucleotidyltransferases, Embryo, Mammalian, Embryonic Stem Cells, Female, Fibroblasts, Gene Expression Regulation, Developmental, Gene Knockout Techniques, Green Fluorescent Proteins, Isoenzymes, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Plasmids, Recombination, Genetic, Transfection
Added March 20, 2013
1 Communities
0 Members
0 Resources
21 MeSH Terms
Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice.
Anastassiadis K, Fu J, Patsch C, Hu S, Weidlich S, Duerschke K, Buchholz F, Edenhofer F, Stewart AF
(2009) Dis Model Mech 2: 508-15
MeSH Terms: Animals, Base Sequence, Cell Line, DNA Nucleotidyltransferases, Embryonic Stem Cells, Escherichia coli, Escherichia coli Proteins, Gene Targeting, Genes, Reporter, Integrases, Ligands, Mice, Mifepristone, Molecular Sequence Data, Plasmids, Progesterone, Prokaryotic Cells, Proteins, RNA, Untranslated, Recombinant Fusion Proteins, Recombinases, Recombination, Genetic, Reproducibility of Results
Added June 25, 2010
1 Communities
0 Members
1 Resources
23 MeSH Terms