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A compendium of G-protein-coupled receptors and cyclic nucleotide regulation of adipose tissue metabolism and energy expenditure.
Ceddia RP, Collins S
(2020) Clin Sci (Lond) 134: 473-512
MeSH Terms: Adipocytes, Adipose Tissue, Animals, Diabetes Mellitus, Type 2, Energy Metabolism, Humans, Lipolysis, Nucleotides, Cyclic, Receptors, G-Protein-Coupled, Signal Transduction
Added March 26, 2020
0 Communities
2 Members
0 Resources
10 MeSH Terms
Inhibition of Glycogen Synthase Kinase 3β as a Treatment for the Prevention of Cognitive Deficits after a Traumatic Brain Injury.
Farr SA, Niehoff ML, Kumar VB, Roby DA, Morley JE
(2019) J Neurotrauma 36: 1869-1875
MeSH Terms: Animals, Brain Injuries, Traumatic, Cognitive Dysfunction, Glycogen Synthase Kinase 3 beta, Maze Learning, Mice, Oligonucleotides, Antisense
Added March 12, 2019
0 Communities
1 Members
0 Resources
7 MeSH Terms
Treating Nonalcoholic Fatty Liver Disease From the Outside In?
Flynn CR
(2019) Cell Mol Gastroenterol Hepatol 7: 682-683
MeSH Terms: Animals, Hepatocytes, Intracellular Signaling Peptides and Proteins, Mice, Non-alcoholic Fatty Liver Disease, Oligonucleotides, Antisense, Protein Serine-Threonine Kinases
Added April 15, 2019
0 Communities
1 Members
0 Resources
7 MeSH Terms
Synthesis and Characterization of Site-Specific O -Alkylguanine DNA-Alkyl Transferase-Oligonucleotide Crosslinks.
Ghodke PP, Albertolle ME, Johnson KM, Guengerich FP
(2019) Curr Protoc Nucleic Acid Chem 76: e74
MeSH Terms: Catalysis, Catalytic Domain, Chromatography, Liquid, Copper, Cross-Linking Reagents, Escherichia coli, O(6)-Methylguanine-DNA Methyltransferase, Oligonucleotides, Polymerization, Tandem Mass Spectrometry, Templates, Genetic, Trypsin
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA.
Mohni KN, Wessel SR, Zhao R, Wojciechowski AC, Luzwick JW, Layden H, Eichman BF, Thompson PS, Mehta KPM, Cortez D
(2019) Cell 176: 144-153.e13
MeSH Terms: 5-Methylcytosine, Apurinic Acid, DNA, DNA Damage, DNA Repair, DNA Replication, DNA, Single-Stranded, DNA-Binding Proteins, Endonucleases, Escherichia coli, Polynucleotides, Proliferating Cell Nuclear Antigen
Added August 26, 2019
0 Communities
1 Members
0 Resources
12 MeSH Terms
Substrate Binding Regulates Redox Signaling in Human DNA Primase.
O'Brien E, Holt ME, Salay LE, Chazin WJ, Barton JK
(2018) J Am Chem Soc 140: 17153-17162
MeSH Terms: DNA, DNA Primase, Electrochemical Techniques, Humans, Iron-Sulfur Proteins, Nucleotides, Oxidation-Reduction, Protein Binding, Protein Domains, Transcription Elongation, Genetic, Transcription Initiation, Genetic
Added March 26, 2019
0 Communities
1 Members
0 Resources
11 MeSH Terms
Targeted Imaging of VCAM-1 mRNA in a Mouse Model of Laser-Induced Choroidal Neovascularization Using Antisense Hairpin-DNA-Functionalized Gold-Nanoparticles.
Uddin MI, Kilburn TC, Yang R, McCollum GW, Wright DW, Penn JS
(2018) Mol Pharm 15: 5514-5520
MeSH Terms: Animals, Biomarkers, Choroid, Choroidal Neovascularization, Disease Models, Animal, Fluorescent Dyes, Gold, Humans, Intravital Microscopy, Lasers, Male, Metal Nanoparticles, Mice, Mice, Inbred C57BL, Molecular Imaging, Molecular Probes, Oligodeoxyribonucleotides, Antisense, Optical Imaging, RNA, Messenger, Vascular Cell Adhesion Molecule-1, Wet Macular Degeneration
Added April 10, 2019
0 Communities
2 Members
0 Resources
21 MeSH Terms
Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase.
Hunter RW, Hughey CC, Lantier L, Sundelin EI, Peggie M, Zeqiraj E, Sicheri F, Jessen N, Wasserman DH, Sakamoto K
(2018) Nat Med 24: 1395-1406
MeSH Terms: Adenosine Monophosphate, Aminoimidazole Carboxamide, Animals, Base Sequence, Chickens, Disease Models, Animal, Fructose-Bisphosphatase, Glucose, Glucose Intolerance, Homeostasis, Humans, Hypoglycemia, Liver, Metformin, Mice, Inbred C57BL, Mutation, Obesity, Prodrugs, Ribonucleotides
Added March 26, 2019
1 Communities
1 Members
0 Resources
19 MeSH Terms
Examination of Signatures of Recent Positive Selection on Genes Involved in Human Sialic Acid Biology.
Moon JM, Aronoff DM, Capra JA, Abbot P, Rokas A
(2018) G3 (Bethesda) 8: 1315-1325
MeSH Terms: Genetic Variation, Humans, N-Acetylneuraminic Acid, Nucleotides, Selection, Genetic
Added March 14, 2018
0 Communities
2 Members
0 Resources
5 MeSH Terms
Modulation of thalamocortical oscillations by TRIP8b, an auxiliary subunit for HCN channels.
Zobeiri M, Chaudhary R, Datunashvili M, Heuermann RJ, Lüttjohann A, Narayanan V, Balfanz S, Meuth P, Chetkovich DM, Pape HC, Baumann A, van Luijtelaar G, Budde T
(2018) Brain Struct Funct 223: 1537-1564
MeSH Terms: Action Potentials, Adenine, Adenylyl Cyclase Inhibitors, Animals, Cardiovascular Agents, Cerebral Cortex, Cyclic AMP, Cyclic GMP, Female, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Male, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Transgenic, Models, Neurological, Neural Pathways, Peroxins, Pyrimidines, Sodium Channel Blockers, Tetrodotoxin, Thalamus, Thionucleotides
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms