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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 92

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New genetic predictors for abacavir tolerance in HLA-B*57:01 positive individuals.
Pavlos R, Deshpande P, Chopra A, Leary S, Strautins K, Nolan D, Thorborn D, Shaefer M, Rauch A, Dunn D, Montaner J, Rachlis A, Almeida CA, Choo L, James I, Redwood AJ, Li Y, Gaudieri S, Mallal SA, Phillips EJ
(2020) Hum Immunol 81: 300-304
MeSH Terms: Allergens, Aminopeptidases, Anti-HIV Agents, Dideoxynucleosides, Drug Hypersensitivity Syndrome, Drug-Related Side Effects and Adverse Reactions, Female, Genetic Association Studies, Genetic Predisposition to Disease, Genotype, HIV Infections, HIV-1, HLA-B Antigens, Humans, Lipopolysaccharide Receptors, Male, Minor Histocompatibility Antigens, Phenotype, Retrospective Studies
Added March 30, 2020
0 Communities
1 Members
0 Resources
19 MeSH Terms
Single-cell transcriptomics reveal polyclonal memory T-cell responses in skin with positive abacavir patch test results.
Redwood AJ, Rwandamuriye F, Chopra A, Leary S, Ram R, McDonnell W, Konvinse K, White K, Pavlos R, Koelle DM, Mallal S, Phillips EJ
(2019) J Allergy Clin Immunol 144: 1413-1416.e7
MeSH Terms: Aged, Anti-HIV Agents, Arthralgia, CD8-Positive T-Lymphocytes, Dideoxynucleosides, Drug Hypersensitivity, Drug-Related Side Effects and Adverse Reactions, Gene Expression Profiling, HLA-B Antigens, Headache, Humans, Immunologic Memory, Lymphocyte Activation, Male, Myalgia, Patch Tests, Single-Cell Analysis, Skin
Added March 30, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Controversies in drug allergy: Testing for delayed reactions.
Phillips EJ, Bigliardi P, Bircher AJ, Broyles A, Chang YS, Chung WH, Lehloenya R, Mockenhaupt M, Peter J, Pirmohamed M, Roujeau JC, Shear NH, Tanno LK, Trubiano J, Valluzzi R, Barbaud A
(2019) J Allergy Clin Immunol 143: 66-73
MeSH Terms: Animals, Asian Continental Ancestry Group, Carbamazepine, Dideoxynucleosides, HLA-B Antigens, HLA-B15 Antigen, Humans, Skin Tests, Stevens-Johnson Syndrome
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Active suppression rather than ignorance: tolerance to abacavir-induced HLA-B*57:01 peptide repertoire alteration.
Phillips EJ, Mallal SA
(2018) J Clin Invest 128: 2746-2749
MeSH Terms: Animals, Dideoxynucleosides, Drug Hypersensitivity, Drug Tolerance, HLA-B Antigens, Mice, Mice, Transgenic, Peptides
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA.
Wauchope OR, Mitchener MM, Beavers WN, Galligan JJ, Camarillo JM, Sanders WD, Kingsley PJ, Shim HN, Blackwell T, Luong T, deCaestecker M, Fessel JP, Marnett LJ
(2018) Nucleic Acids Res 46: 3458-3467
MeSH Terms: Animals, Bone Morphogenetic Protein Receptors, Type II, DNA Adducts, DNA, Mitochondrial, Electron Transport, Endothelial Cells, Gene Expression Regulation, Humans, Hypertension, Pulmonary, Lipid Peroxidation, Mice, Mice, Transgenic, Mitochondria, Mutagenesis, Oxidants, Oxidative Stress, Purine Nucleosides, Reactive Oxygen Species, Superoxides
Added March 14, 2018
0 Communities
3 Members
0 Resources
19 MeSH Terms
Recent Abacavir Use Increases Risk of Type 1 and Type 2 Myocardial Infarctions Among Adults With HIV.
Elion RA, Althoff KN, Zhang J, Moore RD, Gange SJ, Kitahata MM, Crane HM, Drozd DR, Stein JH, Klein MB, Eron JJ, Silverberg MJ, Mathews WC, Justice AC, Sterling TR, Rabkin CS, Mayor AM, Klein DB, Horberg MA, Bosch RJ, Eyawo O, Palella FJ, North American AIDS Cohort Collaboration on Research and Design of IeDEA
(2018) J Acquir Immune Defic Syndr 78: 62-72
MeSH Terms: Adult, Aged, Antirheumatic Agents, CD4 Lymphocyte Count, Cohort Studies, Dideoxynucleosides, Female, HIV Infections, Humans, Male, Middle Aged, Myocardial Infarction, North America, Risk Assessment, Risk Factors
Added March 14, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
HLAs: Key regulators of T-cell-mediated drug hypersensitivity.
Redwood AJ, Pavlos RK, White KD, Phillips EJ
(2018) HLA 91: 3-16
MeSH Terms: B-Lymphocytes, Dideoxynucleosides, Drug Hypersensitivity, HLA-B Antigens, Humans, Immunity, Cellular, Risk Factors, T-Lymphocytes
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Recent advances in the understanding of severe cutaneous adverse reactions.
Adler NR, Aung AK, Ergen EN, Trubiano J, Goh MSY, Phillips EJ
(2017) Br J Dermatol 177: 1234-1247
MeSH Terms: Allopurinol, Anticonvulsants, Carbamazepine, Cephalosporins, Dideoxynucleosides, Drug Eruptions, Drug Interactions, Herpesviridae Infections, Humans, Leukocytes, Mononuclear, Pharmacogenetics, Prospective Studies, Skin Tests, T-Lymphocytes, Virus Activation, Virus Latency, beta-Lactams
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Development of a reliable automated screening system to identify small molecules and biologics that promote human β-cell regeneration.
Aamodt KI, Aramandla R, Brown JJ, Fiaschi-Taesch N, Wang P, Stewart AF, Brissova M, Powers AC
(2016) Am J Physiol Endocrinol Metab 311: E859-E868
MeSH Terms: Activins, Adenosine, Adenosine A2 Receptor Agonists, Adenosine-5'-(N-ethylcarboxamide), Adult, Automation, Cell Culture Techniques, Cell Proliferation, Drug Evaluation, Preclinical, Erythropoietin, Exenatide, Female, GABA Agents, Harmine, Humans, Incretins, Insulin-Secreting Cells, Male, Middle Aged, Monoamine Oxidase Inhibitors, Myostatin, Nucleosides, Peptides, Platelet-Derived Growth Factor, Prolactin, Regeneration, Serotonin, Serotonin Receptor Agonists, Vasodilator Agents, Venoms, Young Adult, gamma-Aminobutyric Acid
Added April 26, 2017
0 Communities
2 Members
0 Resources
32 MeSH Terms
Horizontally acquired genes in early-diverging pathogenic fungi enable the use of host nucleosides and nucleotides.
Alexander WG, Wisecaver JH, Rokas A, Hittinger CT
(2016) Proc Natl Acad Sci U S A 113: 4116-21
MeSH Terms: Fungi, Gene Transfer, Horizontal, Genes, Fungal, Host-Pathogen Interactions, Nucleosides, Nucleotides, Phylogeny
Added April 6, 2017
0 Communities
1 Members
0 Resources
7 MeSH Terms