Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 12

Publication Record

Connections

Successful Aspects of the Coadministration of Sterol 14α-Demethylase Inhibitor VFV and Benznidazole in Experimental Mouse Models of Chagas Disease Caused by the Drug-Resistant Strain of Trypanosoma cruzi.
Guedes-da-Silva FH, Batista DDGJ, Da Silva CF, Pavão BP, Batista MM, Moreira OC, Souza LRQ, Britto C, Rachakonda G, Villalta F, Lepesheva GI, Soeiro MNC
(2019) ACS Infect Dis 5: 365-371
MeSH Terms: 14-alpha Demethylase Inhibitors, Animals, Chagas Disease, Disease Models, Animal, Drug Synergism, Drug Therapy, Combination, Humans, Male, Mice, Nitroimidazoles, Protozoan Proteins, Sterol 14-Demethylase, Trypanocidal Agents, Trypanosoma cruzi
Added July 2, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
In Vivo Imaging of Retinal Hypoxia Using HYPOX-4-Dependent Fluorescence in a Mouse Model of Laser-Induced Retinal Vein Occlusion (RVO).
Uddin MI, Jayagopal A, McCollum GW, Yang R, Penn JS
(2017) Invest Ophthalmol Vis Sci 58: 3818-3824
MeSH Terms: Animals, Disease Models, Animal, Fluorescein Angiography, Fluoresceins, Fluorescent Dyes, Hypoxia, Image Processing, Computer-Assisted, Macular Edema, Male, Mice, Mice, Inbred C57BL, Nitroimidazoles, Radiation-Sensitizing Agents, Retinal Neovascularization, Retinal Vein, Retinal Vein Occlusion, Tomography, Optical Coherence
Added December 21, 2017
0 Communities
2 Members
0 Resources
17 MeSH Terms
Antitrypanosomal Activity of Sterol 14α-Demethylase (CYP51) Inhibitors VNI and VFV in the Swiss Mouse Models of Chagas Disease Induced by the Trypanosoma cruzi Y Strain.
Guedes-da-Silva FH, Batista DG, Da Silva CF, De Araújo JS, Pavão BP, Simões-Silva MR, Batista MM, Demarque KC, Moreira OC, Britto C, Lepesheva GI, Soeiro MN
(2017) Antimicrob Agents Chemother 61:
MeSH Terms: 14-alpha Demethylase Inhibitors, Animals, Chagas Disease, Cyclophosphamide, Cytochrome P-450 Enzyme System, Disease Models, Animal, Drug Administration Schedule, Female, Gene Expression, Humans, Imidazoles, Immunosuppressive Agents, Male, Mice, Models, Molecular, Nitroimidazoles, Oxadiazoles, Parasite Load, Recurrence, Survival Analysis, Trypanocidal Agents, Trypanosoma cruzi
Added July 2, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Quantitative [F]FMISO PET Imaging Shows Reduction of Hypoxia Following Trastuzumab in a Murine Model of HER2+ Breast Cancer.
Sorace AG, Syed AK, Barnes SL, Quarles CC, Sanchez V, Kang H, Yankeelov TE
(2017) Mol Imaging Biol 19: 130-137
MeSH Terms: Animals, Biomarkers, Tumor, Cell Line, Tumor, Disease Models, Animal, Female, Fluorescent Antibody Technique, Mammary Neoplasms, Animal, Misonidazole, Nitroimidazoles, Positron-Emission Tomography, Receptor, ErbB-2, Trastuzumab, Tumor Burden, Tumor Hypoxia
Added April 6, 2017
0 Communities
1 Members
0 Resources
14 MeSH Terms
Different Therapeutic Outcomes of Benznidazole and VNI Treatments in Different Genders in Mouse Experimental Models of Trypanosoma cruzi Infection.
Guedes-da-Silva FH, Batista DG, da Silva CF, Meuser MB, Simões-Silva MR, de Araújo JS, Ferreira CG, Moreira OC, Britto C, Lepesheva GI, Soeiro Mde N
(2015) Antimicrob Agents Chemother 59: 7564-70
MeSH Terms: 14-alpha Demethylase Inhibitors, Animals, Chagas Disease, Cytochrome P-450 Enzyme System, Disease Models, Animal, Drug Administration Schedule, Drug Evaluation, Preclinical, Female, Gene Expression, Imidazoles, Immunosuppressive Agents, Male, Mice, Nitroimidazoles, Oxadiazoles, Parasitemia, Sex Factors, Treatment Outcome, Trypanocidal Agents, Trypanosoma cruzi
Added July 2, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Molecular probes for imaging of hypoxia in the retina.
Evans SM, Kim K, Moore CE, Uddin MI, Capozzi ME, Craft JR, Sulikowski GA, Jayagopal A
(2014) Bioconjug Chem 25: 2030-7
MeSH Terms: Animals, Cell Line, Cell Survival, Fluorescein-5-isothiocyanate, Humans, Hypoxia, Mice, Molecular Imaging, Molecular Probes, Nitroimidazoles, Retina, Retinal Neurons
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Phase I safety, pharmacokinetics, and pharmacogenetics study of the antituberculosis drug PA-824 with concomitant lopinavir-ritonavir, efavirenz, or rifampin.
Dooley KE, Luetkemeyer AF, Park JG, Allen R, Cramer Y, Murray S, Sutherland D, Aweeka F, Koletar SL, Marzan F, Bao J, Savic R, Haas DW, AIDS Clinical Trials Group A5306 Study Team
(2014) Antimicrob Agents Chemother 58: 5245-52
MeSH Terms: Adult, Alkynes, Antitubercular Agents, Antiviral Agents, Benzoxazines, Cyclopropanes, Drug Combinations, Drug Therapy, Combination, Female, Humans, Lopinavir, Male, Middle Aged, Nitroimidazoles, Pharmacogenetics, Rifampin, Ritonavir, Young Adult
Added March 13, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
In vitro and in vivo studies of the antiparasitic activity of sterol 14α-demethylase (CYP51) inhibitor VNI against drug-resistant strains of Trypanosoma cruzi.
Soeiro Mde N, de Souza EM, da Silva CF, Batista Dda G, Batista MM, Pavão BP, Araújo JS, Aiub CA, da Silva PB, Lionel J, Britto C, Kim K, Sulikowski G, Hargrove TY, Waterman MR, Lepesheva GI
(2013) Antimicrob Agents Chemother 57: 4151-63
MeSH Terms: 14-alpha Demethylase Inhibitors, Animals, Chagas Disease, Drug Resistance, Endoplasmic Reticulum, Golgi Apparatus, Imidazoles, Male, Mice, Microscopy, Electron, Transmission, Nitroimidazoles, Oxadiazoles, Protozoan Proteins, Sterol 14-Demethylase, Thiazoles, Triazoles, Trypanocidal Agents, Trypanosoma cruzi
Added March 7, 2014
0 Communities
2 Members
0 Resources
18 MeSH Terms
Mapping serum albumin adducts of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by data-dependent tandem mass spectrometry.
Peng L, Dasari S, Tabb DL, Turesky RJ
(2012) Chem Res Toxicol 25: 2179-93
MeSH Terms: Amino Acid Sequence, Animals, Carcinogens, Cooking, Dipeptidases, Humans, Imidazoles, Leucyl Aminopeptidase, Meat, Molecular Sequence Data, Nitroimidazoles, Oxidation-Reduction, Pronase, Pyridines, Serum Albumin, Tandem Mass Spectrometry, Trypsin
Added June 26, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Pharmacological characterization, structural studies, and in vivo activities of anti-Chagas disease lead compounds derived from tipifarnib.
Buckner FS, Bahia MT, Suryadevara PK, White KL, Shackleford DM, Chennamaneni NK, Hulverson MA, Laydbak JU, Chatelain E, Scandale I, Verlinde CL, Charman SA, Lepesheva GI, Gelb MH
(2012) Antimicrob Agents Chemother 56: 4914-21
MeSH Terms: 14-alpha Demethylase Inhibitors, Administration, Oral, Alkyl and Aryl Transferases, Animals, Chagas Disease, Crystallography, X-Ray, Cytochrome P-450 Enzyme Inhibitors, Cytochrome P-450 Enzyme System, Drug Administration Schedule, Female, Humans, Mice, Models, Molecular, Nitroimidazoles, Quinolones, Structure-Activity Relationship, Triazoles, Trypanocidal Agents, Trypanosoma cruzi
Added July 2, 2021
0 Communities
1 Members
0 Resources
MeSH Terms