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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 13

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Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral Egress and Protect from Lethal Influenza Infection in Mice.
Gilchuk IM, Bangaru S, Gilchuk P, Irving RP, Kose N, Bombardi RG, Thornburg NJ, Creech CB, Edwards KM, Li S, Turner HL, Yu W, Zhu X, Wilson IA, Ward AB, Crowe JE
(2019) Cell Host Microbe 26: 715-728.e8
MeSH Terms: Animals, Antibodies, Heterophile, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Birds, Epitopes, Humans, Influenza A Virus, H7N9 Subtype, Influenza Vaccines, Influenza in Birds, Influenza, Human, Mice, Neuraminidase, Orthomyxoviridae Infections, Pre-Exposure Prophylaxis, Vaccination, Vaccines, Inactivated, Viral Proteins, Virus Release
Added March 31, 2020
0 Communities
1 Members
0 Resources
20 MeSH Terms
Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Zhu X, Turner HL, Lang S, McBride R, Bangaru S, Gilchuk IM, Yu W, Paulson JC, Crowe JE, Ward AB, Wilson IA
(2019) Cell Host Microbe 26: 729-738.e4
MeSH Terms: Animals, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Antiviral Agents, Cryoelectron Microscopy, Epitopes, Humans, Influenza A Virus, H7N9 Subtype, Influenza Vaccines, Neuraminidase, Orthomyxoviridae Infections, Viral Proteins
Added March 31, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
Antibody Determinants of Influenza Immunity.
Crowe JE
(2019) J Infect Dis 219: S21-S29
MeSH Terms: Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Antigens, Viral, B-Lymphocytes, Cross Reactions, Genetic Drift, Hemagglutinin Glycoproteins, Influenza Virus, Humans, Immunologic Memory, Influenza A virus, Influenza Vaccines, Influenza, Human, Neuraminidase, Point Mutation, Vaccination, Vaccines, Inactivated
Added March 31, 2019
0 Communities
1 Members
0 Resources
17 MeSH Terms
Influenza viruses with receptor-binding N1 neuraminidases occur sporadically in several lineages and show no attenuation in cell culture or mice.
Hooper KA, Crowe JE, Bloom JD
(2015) J Virol 89: 3737-45
MeSH Terms: Animals, Cell Line, Disease Models, Animal, Dogs, Female, Humans, Influenza A Virus, H1N1 Subtype, Influenza A Virus, H5N1 Subtype, Mice, Inbred BALB C, Mutant Proteins, Mutation, Missense, Neuraminidase, Orthomyxoviridae Infections, Protein Binding, Receptors, Virus, Reverse Genetics, Viral Proteins, Virus Attachment, Virus Cultivation
Added February 2, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
The Nogo receptor NgR1 mediates infection by mammalian reovirus.
Konopka-Anstadt JL, Mainou BA, Sutherland DM, Sekine Y, Strittmatter SM, Dermody TS
(2014) Cell Host Microbe 15: 681-91
MeSH Terms: Animals, CHO Cells, Capsid Proteins, Cell Adhesion Molecules, Cell Membrane, Cricetulus, GPI-Linked Proteins, Host-Pathogen Interactions, Humans, Mice, Mutant Strains, Myelin Proteins, Neuraminidase, Neurons, Nogo Receptor 1, Receptors, Cell Surface, Reoviridae, Reoviridae Infections, Virion
Added January 21, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase.
Hayakawa M, Toda N, Carrillo N, Thornburg NJ, Crowe JE, Barbas CF
(2012) Chembiochem 13: 2191-5
MeSH Terms: Animals, Antibodies, Monoclonal, Antiviral Agents, Click Chemistry, Fructose-Bisphosphate Aldolase, Humans, Immunoconjugates, Influenza A virus, Influenza, Human, Mice, Models, Molecular, Neuraminidase, Orthomyxoviridae Infections, Zanamivir
Added October 28, 2012
0 Communities
1 Members
0 Resources
14 MeSH Terms
Reovirus preferentially infects the basolateral surface and is released from the apical surface of polarized human respiratory epithelial cells.
Excoffon KJ, Guglielmi KM, Wetzel JD, Gansemer ND, Campbell JA, Dermody TS, Zabner J
(2008) J Infect Dis 197: 1189-97
MeSH Terms: Animals, Cell Adhesion Molecules, Cell Polarity, Electric Impedance, Humans, Immunoglobulins, Immunohistochemistry, L Cells, Mice, Microscopy, Confocal, Neuraminidase, Orthoreovirus, Mammalian, Reassortant Viruses, Receptors, Cell Surface, Reoviridae Infections, Respiratory Mucosa, Respiratory Tract Infections, Tight Junctions, Virus Shedding
Added December 10, 2013
0 Communities
1 Members
0 Resources
19 MeSH Terms
Emergence of influenza A virus variants after prolonged shedding from pheasants.
Humberd J, Boyd K, Webster RG
(2007) J Virol 81: 4044-51
MeSH Terms: Amino Acid Sequence, Amino Acid Substitution, Animals, Antibodies, Viral, Antigens, Viral, Birds, Bursa of Fabricius, Cecum, Chick Embryo, Ferrets, Genetic Drift, Genetic Variation, Hemagglutinin Glycoproteins, Influenza Virus, Histocytochemistry, Influenza A virus, Influenza in Birds, Intestine, Large, Male, Molecular Sequence Data, Mutation, Missense, Neuraminidase, Trachea, Viral Proteins, Virus Replication, Virus Shedding
Added March 5, 2014
0 Communities
1 Members
0 Resources
25 MeSH Terms
Reovirus binding to cell surface sialic acid potentiates virus-induced apoptosis.
Connolly JL, Barton ES, Dermody TS
(2001) J Virol 75: 4029-39
MeSH Terms: Animals, Apoptosis, Capsid Proteins, Cell Membrane, HeLa Cells, Humans, L Cells, Mice, N-Acetylneuraminic Acid, NF-kappa B, Neuraminidase, Rabbits, Receptors, Virus, Reoviridae, Viral Proteins
Added December 10, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms
Infectious subvirion particles of reovirus type 3 Dearing exhibit a loss in infectivity and contain a cleaved sigma 1 protein.
Nibert ML, Chappell JD, Dermody TS
(1995) J Virol 69: 5057-67
MeSH Terms: Animals, Antibodies, Monoclonal, Capsid Proteins, Chymotrypsin, Hemagglutinins, Viral, Hydrolysis, L Cells, Mammalian orthoreovirus 3, Membrane Fusion, Mice, Neuraminidase, Trypsin, Viral Proteins, Virion, Virulence
Added December 10, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms