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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 5 of 5

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Nedd4-2 regulates surface expression and may affect N-glycosylation of hyperpolarization-activated cyclic nucleotide-gated (HCN)-1 channels.
Wilkars W, Wollberg J, Mohr E, Han M, Chetkovich DM, Bähring R, Bender RA
(2014) FASEB J 28: 2177-90
MeSH Terms: Amino Acid Motifs, Animals, Brain, Cell Membrane, Down-Regulation, Electrophysiology, Endosomal Sorting Complexes Required for Transport, Female, Gene Expression Regulation, Glycosylation, HEK293 Cells, Humans, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Nedd4 Ubiquitin Protein Ligases, Oocytes, Protein Structure, Tertiary, Rats, Rats, Wistar, Receptors, Cytoplasmic and Nuclear, Ubiquitin-Protein Ligases, Xenopus Proteins, Xenopus laevis
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
NEDD4L is downregulated in colorectal cancer and inhibits canonical WNT signaling.
Tanksley JP, Chen X, Coffey RJ
(2013) PLoS One 8: e81514
MeSH Terms: Colorectal Neoplasms, Down-Regulation, Endosomal Sorting Complexes Required for Transport, Gene Expression Regulation, Neoplastic, Humans, Nedd4 Ubiquitin Protein Ligases, Tumor Suppressor Proteins, Ubiquitin-Protein Ligases, Wnt Signaling Pathway
Added March 27, 2014
1 Communities
1 Members
0 Resources
9 MeSH Terms
Anterograde transport of surfactant protein C proprotein to distal processing compartments requires PPDY-mediated association with Nedd4 ubiquitin ligases.
Kotorashvili A, Russo SJ, Mulugeta S, Guttentag S, Beers MF
(2009) J Biol Chem 284: 16667-16678
MeSH Terms: Cells, Cultured, Endosomal Sorting Complexes Required for Transport, Epithelial Cells, Green Fluorescent Proteins, Humans, Lung, Mutagenesis, Mutant Chimeric Proteins, Nedd4 Ubiquitin Protein Ligases, Protein Precursors, Protein Transport, Pulmonary Surfactant-Associated Protein C, RNA, Small Interfering, Transfection, Ubiquitin-Protein Ligases, Ubiquitination
Added January 20, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
Nedd4 mediates ErbB4 JM-a/CYT-1 ICD ubiquitination and degradation in MDCK II cells.
Zeng F, Xu J, Harris RC
(2009) FASEB J 23: 1935-45
MeSH Terms: Amino Acid Motifs, Animals, Cells, Cultured, Dogs, Endosomal Sorting Complexes Required for Transport, Enzyme Inhibitors, ErbB Receptors, Humans, Lysosomes, Mutagenesis, Site-Directed, Nedd4 Ubiquitin Protein Ligases, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Protein Isoforms, Protein Structure, Tertiary, Receptor, ErbB-4, Recombinant Fusion Proteins, Tetradecanoylphorbol Acetate, Ubiquitin, Ubiquitin-Protein Ligases, Ubiquitination
Added August 19, 2013
1 Communities
1 Members
0 Resources
21 MeSH Terms
Inhibition of the epithelial Na+ channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome.
Goulet CC, Volk KA, Adams CM, Prince LS, Stokes JB, Snyder PM
(1998) J Biol Chem 273: 30012-7
MeSH Terms: Animals, COS Cells, Calcium-Binding Proteins, Cell Membrane, Endosomal Sorting Complexes Required for Transport, Epithelium, Hypertension, Ligases, Nedd4 Ubiquitin Protein Ligases, Protein Binding, Rats, Recombinant Fusion Proteins, Sequence Deletion, Sodium Channel Blockers, Syndrome, Ubiquitin-Protein Ligases, Xenopus, Xenopus Proteins
Added June 9, 2010
0 Communities
1 Members
0 Resources
18 MeSH Terms