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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 11

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Constitutively Active SPAK Causes Hyperkalemia by Activating NCC and Remodeling Distal Tubules.
Grimm PR, Coleman R, Delpire E, Welling PA
(2017) J Am Soc Nephrol 28: 2597-2606
MeSH Terms: Aldosterone, Animals, Blood Pressure, Epithelial Sodium Channels, Hydrochlorothiazide, Kidney Tubules, Distal, Mice, Natriuresis, Phosphorylation, Potassium, Potassium Channels, Inwardly Rectifying, Protein Serine-Threonine Kinases, Pseudohypoaldosteronism, Signal Transduction, Sodium Chloride Symporter Inhibitors, Solute Carrier Family 12, Member 3
Added May 3, 2017
0 Communities
1 Members
0 Resources
16 MeSH Terms
Integrated compensatory network is activated in the absence of NCC phosphorylation.
Grimm PR, Lazo-Fernandez Y, Delpire E, Wall SM, Dorsey SG, Weinman EJ, Coleman R, Wade JB, Welling PA
(2015) J Clin Invest 125: 2136-50
MeSH Terms: Amiloride, Ammonia, Animals, Biological Transport, Blood Pressure, Carbonic Anhydrases, Chlorides, Disease Models, Animal, Enzyme Activation, Epithelial Sodium Channels, Gene Expression Profiling, Gene Regulatory Networks, Gitelman Syndrome, Ketoglutaric Acids, Kidney Glomerulus, Male, Mice, Mice, Knockout, Natriuresis, Nephrons, Paracrine Communication, Phosphorylation, Protein Processing, Post-Translational, Protein Serine-Threonine Kinases, Receptors, Notch, Receptors, Purinergic P2, Renal Reabsorption, Signal Transduction, Sodium Chloride, Sodium-Potassium-Chloride Symporters, Solute Carrier Family 12, Member 3
Added May 3, 2017
0 Communities
1 Members
0 Resources
31 MeSH Terms
Role of epoxyeicosatrienoic acids (EETs) in mediation of dopamine's effects in the kidney.
Zhang MZ, Wang Y, Yao B, Gewin L, Wei S, Capdevila JH, Harris RC
(2013) Am J Physiol Renal Physiol 305: F1680-6
MeSH Terms: Animals, Arachidonic Acid, Aromatic-L-Amino-Acid Decarboxylases, Catechol O-Methyltransferase, Cells, Cultured, Cytochrome P-450 CYP2J2, Cytochrome P-450 Enzyme System, Cytochrome P450 Family 2, Diet, Sodium-Restricted, Dihydroxyphenylalanine, Disease Models, Animal, Diuresis, Dopamine, Dopamine Agents, Hypertension, Kidney, Male, Mice, Mice, Knockout, Natriuresis, Sodium Chloride, Dietary
Added February 26, 2014
1 Communities
4 Members
0 Resources
21 MeSH Terms
Induction of the renal stanniocalcin-1 gene in rodents by water deprivation.
Turner J, Sazonova O, Wang H, Pozzi A, Wagner GF
(2010) Mol Cell Endocrinol 328: 8-15
MeSH Terms: Animals, Drinking, Female, Gene Expression Regulation, Glycoproteins, Kidney, Male, Mice, Mice, Inbred C57BL, Natriuresis, Nephrectomy, Rats, Rats, Wistar, Rodentia, Time Factors, Up-Regulation, Water Deprivation, Water-Electrolyte Imbalance
Added February 24, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Recovery from renal ischemia-reperfusion injury is associated with altered renal hemodynamics, blunted pressure natriuresis, and sodium-sensitive hypertension.
Pechman KR, De Miguel C, Lund H, Leonard EC, Basile DP, Mattson DL
(2009) Am J Physiol Regul Integr Comp Physiol 297: R1358-63
MeSH Terms: Animals, Blood Pressure, Creatinine, Disease Models, Animal, Glomerular Filtration Rate, Hypertension, Renal, Kidney, Kidney Cortex, Kidney Diseases, Kidney Medulla, Male, Natriuresis, Rats, Rats, Sprague-Dawley, Recovery of Function, Regional Blood Flow, Reperfusion Injury, Sodium, Sodium Chloride, Dietary
Added March 6, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Increased dietary NaCl induces renal medullary PGE2 production and natriuresis via the EP2 receptor.
Chen J, Zhao M, He W, Milne GL, Howard JR, Morrow J, H├ębert RL, Breyer RM, Chen J, Hao CM
(2008) Am J Physiol Renal Physiol 295: F818-25
MeSH Terms: Animals, Dinoprostone, Kidney Medulla, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Natriuresis, Receptors, Prostaglandin E, Receptors, Prostaglandin E, EP2 Subtype, Sodium, Sodium Chloride, Dietary
Added December 21, 2013
2 Communities
2 Members
0 Resources
12 MeSH Terms
Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention.
Ge Y, Bagnall A, Stricklett PK, Strait K, Webb DJ, Kotelevtsev Y, Kohan DE
(2006) Am J Physiol Renal Physiol 291: F1274-80
MeSH Terms: Aldosterone, Animal Feed, Animals, Blood Pressure, Endothelin-1, Hypertension, Renal, Kidney Tubules, Collecting, Mice, Mice, Knockout, Natriuresis, Paracrine Communication, Receptor, Endothelin B, Renin, Sodium Chloride, Dietary
Added September 9, 2013
0 Communities
0 Members
1 Resources
14 MeSH Terms
Clonidine for the treatment of supine hypertension and pressure natriuresis in autonomic failure.
Shibao C, Gamboa A, Abraham R, Raj SR, Diedrich A, Black B, Robertson D, Biaggioni I
(2006) Hypertension 47: 522-6
MeSH Terms: Aged, Aged, 80 and over, Antihypertensive Agents, Autonomic Nervous System, Autonomic Nervous System Diseases, Blood Pressure, Clonidine, Female, Humans, Hypertension, Hypotension, Orthostatic, Male, Middle Aged, Natriuresis, Nitroglycerin, Supine Position, Sympathetic Nervous System, Sympatholytics, Vasodilator Agents
Added December 10, 2013
0 Communities
4 Members
0 Resources
19 MeSH Terms
Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II.
Qi Z, Hao CM, Langenbach RI, Breyer RM, Redha R, Morrow JD, Breyer MD
(2002) J Clin Invest 110: 61-9
MeSH Terms: Angiotensin II, Animals, Anti-Inflammatory Agents, Non-Steroidal, Blood Pressure, Cyclooxygenase 1, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors, Diuresis, Female, Humans, Isoenzymes, Kidney, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Natriuresis, Prostaglandin-Endoperoxide Synthases, Prostaglandins, Renal Circulation
Added December 21, 2013
0 Communities
1 Members
0 Resources
21 MeSH Terms
A novel variant of the beta-subunit of the amiloride-sensitive sodium channel in African Americans.
Su YR, Rutkowski MP, Klanke CA, Wu X, Cui Y, Pun RY, Carter V, Reif M, Menon AG
(1996) J Am Soc Nephrol 7: 2543-9
MeSH Terms: Aldosterone, Amiloride, Amino Acid Sequence, B-Lymphocytes, Base Sequence, Blacks, Blood Pressure, Codon, DNA, Diuretics, Electric Conductivity, Epithelial Sodium Channels, Genetic Variation, Humans, In Vitro Techniques, Membrane Potentials, Natriuresis, Sodium Channels, Whites
Added December 10, 2013
0 Communities
1 Members
0 Resources
19 MeSH Terms