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Results: 1 to 8 of 8

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Functional and mechanistic investigation of Shikonin in scarring.
Xie Y, Fan C, Dong Y, Lynam E, Leavesley DI, Li K, Su Y, Yang Y, Upton Z
(2015) Chem Biol Interact 228: 18-27
MeSH Terms: Apoptosis, Cell Proliferation, Cell Survival, Cells, Cultured, Cicatrix, Collagen, Dose-Response Relationship, Drug, Humans, Keratinocytes, Naphthoquinones, Structure-Activity Relationship
Added January 20, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Structure and Stereochemical Determination of Hypogeamicins from a Cave-Derived Actinomycete.
Derewacz DK, McNees CR, Scalmani G, Covington CL, Shanmugam G, Marnett LJ, Polavarapu PL, Bachmann BO
(2014) J Nat Prod 77: 1759-63
MeSH Terms: Actinobacteria, Caves, Circular Dichroism, Humans, Models, Molecular, Molecular Conformation, Molecular Structure, Naphthoquinones, Nuclear Magnetic Resonance, Biomolecular, Optical Rotatory Dispersion, Stereoisomerism
Added February 12, 2015
0 Communities
3 Members
0 Resources
11 MeSH Terms
Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone.
Przybysz AJ, Choe KP, Roberts LJ, Strange K
(2009) Mech Ageing Dev 130: 357-69
MeSH Terms: Adaptation, Physiological, Age Factors, Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Cytoprotection, DNA-Binding Proteins, Dose-Response Relationship, Drug, Down-Regulation, Forkhead Transcription Factors, Gene Expression Profiling, Mutation, Naphthoquinones, Oligonucleotide Array Sequence Analysis, Oxidative Stress, RNA Interference, Signal Transduction, Transcription Factors, Transcriptional Activation, Xenobiotics
Added December 10, 2013
0 Communities
1 Members
0 Resources
20 MeSH Terms
Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2.
Zhao B, Lamb DC, Lei L, Kelly SL, Yuan H, Hachey DL, Waterman MR
(2007) Biochemistry 46: 8725-33
MeSH Terms: Bacterial Proteins, Binding Sites, Carbon-Carbon Double Bond Isomerases, Crystallography, X-Ray, Cytochrome P-450 Enzyme System, Dimerization, Models, Molecular, Naphthoquinones, Oxidation-Reduction, Pigments, Biological, Protein Conformation, Streptomyces coelicolor, Substrate Specificity
Added March 20, 2014
0 Communities
2 Members
0 Resources
13 MeSH Terms
Ligand-assisted inhibition in cytochrome P450 158A2 from Streptomyces coelicolor A3(2).
Zhao B, Waterman MR, Isin EM, Sundaramoorthy M, Podust LM
(2006) Biochemistry 45: 7493-500
MeSH Terms: Binding Sites, Crystallization, Cytochrome P-450 Enzyme Inhibitors, Escherichia coli, Hydrogen Bonding, Imidazoles, Kinetics, Ligands, Malonates, Mixed Function Oxygenases, Models, Molecular, Naphthoquinones, Protein Conformation, Protein Structure, Secondary, Streptomyces coelicolor
Added February 12, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Binding of two flaviolin substrate molecules, oxidative coupling, and crystal structure of Streptomyces coelicolor A3(2) cytochrome P450 158A2.
Zhao B, Guengerich FP, Bellamine A, Lamb DC, Izumikawa M, Lei L, Podust LM, Sundaramoorthy M, Kalaitzis JA, Reddy LM, Kelly SL, Moore BS, Stec D, Voehler M, Falck JR, Shimada T, Waterman MR
(2005) J Biol Chem 280: 11599-607
MeSH Terms: Crystallization, Cytochrome P-450 Enzyme System, Dimerization, Naphthoquinones, Oxidation-Reduction, Protein Conformation, Streptomyces coelicolor
Added March 5, 2014
0 Communities
2 Members
0 Resources
7 MeSH Terms
Determination of rate constants of the reactions of thiols with superoxide radical by electron paramagnetic resonance: critical remarks on spectrophotometric approaches.
Dikalov S, Khramtsov V, Zimmer G
(1996) Arch Biochem Biophys 326: 207-18
MeSH Terms: Adrenochrome, Cyclic N-Oxides, Cytochrome c Group, Electron Spin Resonance Spectroscopy, Evaluation Studies as Topic, In Vitro Techniques, Kinetics, NADPH-Ferrihemoprotein Reductase, Naphthoquinones, Oxidation-Reduction, Spectrophotometry, Spin Labels, Sulfhydryl Compounds, Superoxides
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Hydroxyl radical generation by oligonucleotide derivatives of anthracycline antibiotic and synthetic quinone.
Dikalov SI, Rumyantseva GV, Weiner LM, Sergejev DS, Frolova EI, Godovikova TS, Zarytova VF
(1991) Chem Biol Interact 77: 325-39
MeSH Terms: Base Sequence, Cyclic N-Oxides, Daunorubicin, Electron Spin Resonance Spectroscopy, Hydroxides, Hydroxyl Radical, Magnetic Resonance Spectroscopy, Molecular Sequence Data, Molecular Structure, NADPH-Ferrihemoprotein Reductase, Naphthoquinones, Oligonucleotides, Spin Labels
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms