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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 9 of 9

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Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9.
Rhoads JP, Lukens JR, Wilhelm AJ, Moore JL, Mendez-Fernandez Y, Kanneganti TD, Major AS
(2017) J Immunol 198: 2105-2114
MeSH Terms: Animals, Antibodies, Antigen-Antibody Complex, CARD Signaling Adaptor Proteins, Cells, Cultured, Cytokines, Dendritic Cells, Inflammasomes, Inflammation Mediators, Lipoproteins, LDL, Macrophages, Mice, Mice, Inbred C57BL, NLR Family, Pyrin Domain-Containing 3 Protein, Receptor Cross-Talk, Receptors, IgG, Signal Transduction, Th17 Cells, Toll-Like Receptors
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications.
Hardbower DM, Asim M, Luis PB, Singh K, Barry DP, Yang C, Steeves MA, Cleveland JL, Schneider C, Piazuelo MB, Gobert AP, Wilson KT
(2017) Proc Natl Acad Sci U S A 114: E751-E760
MeSH Terms: Animals, Cell Line, Citrobacter rodentium, Colitis, Colon, Cytokines, Enterobacteriaceae Infections, Gastric Mucosa, Gastritis, Helicobacter Infections, Helicobacter pylori, Histones, Humans, Macrophage Activation, Macrophages, Male, Mice, NLR Family, Pyrin Domain-Containing 3 Protein, Ornithine Decarboxylase, Putrescine
Added January 19, 2017
0 Communities
1 Members
0 Resources
20 MeSH Terms
IL-1β and Inflammasome Activity Link Inflammation to Abnormal Fetal Airway Development.
Stouch AN, McCoy AM, Greer RM, Lakhdari O, Yull FE, Blackwell TS, Hoffman HM, Prince LS
(2016) J Immunol 196: 3411-20
MeSH Terms: Animals, Bronchopulmonary Dysplasia, Carrier Proteins, Disease Models, Animal, Inflammasomes, Inflammation, Interleukin-1beta, Lipopolysaccharides, Lung, Macrophages, Mice, Mice, Inbred C57BL, Mice, Knockout, NF-kappa B, NLR Family, Pyrin Domain-Containing 3 Protein, Signal Transduction
Added May 4, 2017
1 Communities
1 Members
0 Resources
16 MeSH Terms
Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality.
Zoccal KF, Sorgi CA, Hori JI, Paula-Silva FW, Arantes EC, Serezani CH, Zamboni DS, Faccioli LH
(2016) Nat Commun 7: 10760
MeSH Terms: Animals, Arachidonate 5-Lipoxygenase, Blotting, Western, Carrier Proteins, Celecoxib, Cyclic AMP, Cyclic AMP-Dependent Protein Kinases, Cyclooxygenase Inhibitors, Dinoprostone, In Vitro Techniques, Indoles, Indomethacin, Inflammasomes, Interleukin-1beta, Leukotriene B4, Lipoxygenase Inhibitors, Macrophages, Macrophages, Peritoneal, Mice, Mice, Knockout, NF-kappa B, NLR Family, Pyrin Domain-Containing 3 Protein, Phosphoproteins, Prostaglandin Antagonists, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP4 Subtype, Reverse Transcriptase Polymerase Chain Reaction, Scorpion Stings, Scorpion Venoms, Scorpions, Xanthones
Added May 4, 2017
0 Communities
1 Members
0 Resources
31 MeSH Terms
Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome.
Gelfand BD, Wright CB, Kim Y, Yasuma T, Yasuma R, Li S, Fowler BJ, Bastos-Carvalho A, Kerur N, Uittenbogaard A, Han YS, Lou D, Kleinman ME, McDonald WH, Núñez G, Georgel P, Dunaief JL, Ambati J
(2015) Cell Rep 11: 1686-93
MeSH Terms: Alu Elements, Animals, Carrier Proteins, Caspase 1, DEAD-box RNA Helicases, Inflammasomes, Iron, Mice, Mice, Inbred C57BL, NLR Family, Pyrin Domain-Containing 3 Protein, RNA-Binding Proteins, Retinal Pigment Epithelium, Ribonuclease III
Added January 26, 2016
0 Communities
1 Members
0 Resources
13 MeSH Terms
Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection.
Callaway JB, Smith SA, McKinnon KP, de Silva AM, Crowe JE, Ting JP
(2015) J Biol Chem 290: 17306-20
MeSH Terms: Antibodies, Viral, Antibody-Dependent Enhancement, Antigen-Antibody Complex, Carrier Proteins, Caspase 1, Cells, Cultured, Dengue, Dengue Virus, Glyburide, Humans, Interleukin-1beta, Intracellular Signaling Peptides and Proteins, MAP Kinase Signaling System, Monocytes, NLR Family, Pyrin Domain-Containing 3 Protein, Protein-Tyrosine Kinases, RNA, Messenger, RNA, Small Interfering, Syk Kinase, Virus Replication
Added January 26, 2016
0 Communities
1 Members
0 Resources
20 MeSH Terms
Dysregulation of Escherichia coli α-hemolysin expression alters the course of acute and persistent urinary tract infection.
Nagamatsu K, Hannan TJ, Guest RL, Kostakioti M, Hadjifrangiskou M, Binkley J, Dodson K, Raivio TL, Hultgren SJ
(2015) Proc Natl Acad Sci U S A 112: E871-80
MeSH Terms: Acute Disease, Animals, Apoptosis, Bacterial Proteins, Carrier Proteins, Caspase 1, Chronic Disease, Colony Count, Microbial, Disease Progression, Enzyme Activation, Escherichia coli Infections, Escherichia coli Proteins, Female, Gene Expression Regulation, Bacterial, Hemolysin Proteins, Humans, Inflammasomes, Interleukin-1beta, Mice, Models, Biological, NLR Family, Pyrin Domain-Containing 3 Protein, Signal Transduction, Urinary Bladder, Urinary Tract Infections, Uropathogenic Escherichia coli, Virulence
Added February 16, 2016
0 Communities
1 Members
0 Resources
26 MeSH Terms
Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis.
Ippagunta SK, Brand DD, Luo J, Boyd KL, Calabrese C, Stienstra R, Van de Veerdonk FL, Netea MG, Joosten LA, Lamkanfi M, Kanneganti TD
(2010) J Biol Chem 285: 12454-62
MeSH Terms: Animals, Apoptosis Regulatory Proteins, Arthritis, Experimental, Autoantibodies, CARD Signaling Adaptor Proteins, Carrier Proteins, Caspase 1, Collagen, Cytoskeletal Proteins, Dendritic Cells, Humans, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Mice, Knockout, NLR Family, Pyrin Domain-Containing 3 Protein, T-Lymphocytes
Added March 20, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1.
Thomas PG, Dash P, Aldridge JR, Ellebedy AH, Reynolds C, Funk AJ, Martin WJ, Lamkanfi M, Webby RJ, Boyd KL, Doherty PC, Kanneganti TD
(2009) Immunity 30: 566-75
MeSH Terms: Animals, Antigen-Presenting Cells, Carrier Proteins, Caspase 1, Cells, Cultured, Gene Expression Regulation, Genetic Predisposition to Disease, Immunity, Innate, Influenza A virus, Interleukin-1beta, Mice, Mice, Inbred C57BL, Mice, Knockout, NLR Family, Pyrin Domain-Containing 3 Protein
Added March 5, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms