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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 69

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An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles.
Evans BC, Fletcher RB, Kilchrist KV, Dailing EA, Mukalel AJ, Colazo JM, Oliver M, Cheung-Flynn J, Brophy CM, Tierney JW, Isenberg JS, Hankenson KD, Ghimire K, Lander C, Gersbach CA, Duvall CL
(2019) Nat Commun 10: 5012
MeSH Terms: Acrylates, Animals, Anions, Cations, Cell Line, Cells, Cultured, Drug Delivery Systems, Endosomes, HEK293 Cells, Humans, Intracellular Space, MCF-7 Cells, Macromolecular Substances, Mice, NIH 3T3 Cells, Nanoparticles, Peptides, Polymers, RAW 264.7 Cells, Rats, Reproducibility of Results
Added November 7, 2019
0 Communities
3 Members
0 Resources
21 MeSH Terms
ALK Fusion Partners Impact Response to ALK Inhibition: Differential Effects on Sensitivity, Cellular Phenotypes, and Biochemical Properties.
Childress MA, Himmelberg SM, Chen H, Deng W, Davies MA, Lovly CM
(2018) Mol Cancer Res 16: 1724-1736
MeSH Terms: Anaplastic Lymphoma Kinase, Animals, Cell Line, Tumor, Mice, NIH 3T3 Cells, Oncogene Proteins, Fusion, Phenotype, Protein Kinase Inhibitors
Added September 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Exploring the potential of polyurethane-based soft foam as cell-free scaffold for soft tissue regeneration.
Gerges I, Tamplenizza M, Martello F, Recordati C, Martelli C, Ottobrini L, Tamplenizza M, Guelcher SA, Tocchio A, Lenardi C
(2018) Acta Biomater 73: 141-153
MeSH Terms: Adipose Tissue, Animals, Mice, NIH 3T3 Cells, Neovascularization, Physiologic, Polyurethanes, Regeneration, Tissue Scaffolds
Added March 20, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma.
Loganathan SN, Tang N, Fleming JT, Ma Y, Guo Y, Borinstein SC, Chiang C, Wang J
(2016) Oncotarget 7: 43504-43517
MeSH Terms: Animals, Antineoplastic Agents, Autocrine Communication, Azepines, Bone Neoplasms, Cell Line, Tumor, Cell Proliferation, Cell Survival, Epigenesis, Genetic, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, Insulin-Like Growth Factor I, Mice, Mice, Nude, NIH 3T3 Cells, Oncogene Proteins, Fusion, Proteins, Proto-Oncogene Protein c-fli-1, Proto-Oncogene Proteins c-akt, RNA-Binding Protein EWS, Receptor, IGF Type 1, Receptors, Somatomedin, Sarcoma, Ewing, Signal Transduction, Transcription, Genetic, Triazoles, Xenograft Model Antitumor Assays
Added November 19, 2016
0 Communities
3 Members
0 Resources
29 MeSH Terms
Interstitial Pressure in Pancreatic Ductal Adenocarcinoma Is Dominated by a Gel-Fluid Phase.
DuFort CC, DelGiorno KE, Carlson MA, Osgood RJ, Zhao C, Huang Z, Thompson CB, Connor RJ, Thanos CD, Scott Brockenbrough J, Provenzano PP, Frost GI, Michael Shepard H, Hingorani SR
(2016) Biophys J 110: 2106-19
MeSH Terms: Adenocarcinoma, Animals, Extracellular Fluid, Hyaluronic Acid, Hydrostatic Pressure, Mice, NIH 3T3 Cells, Pancreatic Neoplasms, Viscosity
Added March 13, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
WIP1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma.
Wen J, Lee J, Malhotra A, Nahta R, Arnold AR, Buss MC, Brown BD, Maier C, Kenney AM, Remke M, Ramaswamy V, Taylor MD, Castellino RC
(2016) Oncogene 35: 5552-5564
MeSH Terms: Animals, Biomarkers, Cell Cycle, Cell Line, Tumor, Cell Proliferation, Cell Transformation, Neoplastic, Cerebellar Neoplasms, Gene Knockdown Techniques, Hedgehog Proteins, Humans, Medulloblastoma, Mice, Mice, Transgenic, NIH 3T3 Cells, Neural Stem Cells, Protein Phosphatase 2C, Signal Transduction, Tumor Suppressor Protein p53
Added April 25, 2016
0 Communities
1 Members
0 Resources
18 MeSH Terms
MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer.
Edmonds MD, Boyd KL, Moyo T, Mitra R, Duszynski R, Arrate MP, Chen X, Zhao Z, Blackwell TS, Andl T, Eischen CM
(2016) J Clin Invest 126: 349-64
MeSH Terms: Adenocarcinoma, Adenocarcinoma of Lung, Animals, Cell Line, Tumor, Female, Humans, Lung Neoplasms, MAP Kinase Signaling System, Male, Mice, MicroRNAs, Mutation, NIH 3T3 Cells, Proto-Oncogene Proteins p21(ras), ras Proteins
Added February 22, 2016
1 Communities
1 Members
0 Resources
15 MeSH Terms
Vinculin controls talin engagement with the actomyosin machinery.
Atherton P, Stutchbury B, Wang DY, Jethwa D, Tsang R, Meiler-Rodriguez E, Wang P, Bate N, Zent R, Barsukov IL, Goult BT, Critchley DR, Ballestrem C
(2015) Nat Commun 6: 10038
MeSH Terms: Actin Cytoskeleton, Actins, Actomyosin, Animals, Cell Polarity, Focal Adhesions, Mice, NIH 3T3 Cells, Protein Binding, Protein Structure, Tertiary, Talin, Vinculin
Added February 4, 2016
1 Communities
1 Members
0 Resources
12 MeSH Terms
Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif.
Thomas LR, Foshage AM, Weissmiller AM, Popay TM, Grieb BC, Qualls SJ, Ng V, Carboneau B, Lorey S, Eischen CM, Tansey WP
(2016) Oncogene 35: 3613-8
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Binding Sites, Cell Transformation, Neoplastic, Conserved Sequence, Evolution, Molecular, HEK293 Cells, Host Cell Factor C1, Humans, Immunoprecipitation, Mice, Mutation, NIH 3T3 Cells, Protein Binding, Proto-Oncogene Proteins c-myc, Sequence Homology, Amino Acid
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC.
Thomas LR, Wang Q, Grieb BC, Phan J, Foshage AM, Sun Q, Olejniczak ET, Clark T, Dey S, Lorey S, Alicie B, Howard GC, Cawthon B, Ess KC, Eischen CM, Zhao Z, Fesik SW, Tansey WP
(2015) Mol Cell 58: 440-52
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Anisotropy, Binding Sites, Carcinogenesis, Chromatin, Fluorescence Polarization, HEK293 Cells, Humans, Intracellular Signaling Peptides and Proteins, Mice, Mice, Nude, Models, Molecular, Molecular Sequence Data, Mutation, NIH 3T3 Cells, Protein Binding, Protein Structure, Tertiary, Proteins, Proto-Oncogene Proteins c-myc, Sequence Homology, Amino Acid, Two-Hybrid System Techniques
Added May 15, 2015
0 Communities
3 Members
0 Resources
23 MeSH Terms