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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 13

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Apoptosis signal-regulating kinase 1 activation by Nox1-derived oxidants is required for TNFα receptor endocytosis.
Choi H, Stark RJ, Raja BS, Dikalova A, Lamb FS
(2019) Am J Physiol Heart Circ Physiol 316: H1528-H1537
MeSH Terms: Animals, Aorta, Thoracic, Cells, Cultured, Endocytosis, MAP Kinase Kinase Kinase 5, Mice, Inbred C57BL, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, NADPH Oxidase 1, Receptors, Tumor Necrosis Factor, Type I, Signal Transduction, Superoxides, Tumor Necrosis Factor-alpha
Added April 3, 2019
0 Communities
1 Members
0 Resources
13 MeSH Terms
Activation of NADPH oxidases leads to DNA damage in esophageal cells.
Bhardwaj V, Gokulan RC, Horvat A, Yermalitskaya L, Korolkova O, Washington KM, El-Rifai W, Dikalov SI, Zaika AI
(2017) Sci Rep 7: 9956
MeSH Terms: Barrett Esophagus, Bile Acids and Salts, Cells, Cultured, DNA Damage, Epithelial Cells, Humans, NADPH Oxidase 1, NADPH Oxidase 2, Reactive Oxygen Species
Added March 26, 2019
0 Communities
1 Members
0 Resources
9 MeSH Terms
LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis.
Choi H, Ettinger N, Rohrbough J, Dikalova A, Nguyen HN, Lamb FS
(2016) Free Radic Biol Med 101: 413-423
MeSH Terms: Cell Line, Cyclopentanes, Endocytosis, Gene Expression Regulation, HEK293 Cells, Humans, Indans, JNK Mitogen-Activated Protein Kinases, Membrane Proteins, Myocytes, Smooth Muscle, NADPH Oxidase 1, NF-kappa B, Phosphorylation, Protein Subunits, RNA, Small Interfering, Receptors, Tumor Necrosis Factor, Type I, Signal Transduction, Superoxide Dismutase, Superoxides, Tumor Necrosis Factor-alpha, Vascular Cell Adhesion Molecule-1
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
c-Jun N-terminal kinase attenuates TNFα signaling by reducing Nox1-dependent endosomal ROS production in vascular smooth muscle cells.
Choi H, Dikalova A, Stark RJ, Lamb FS
(2015) Free Radic Biol Med 86: 219-27
MeSH Terms: Animals, Cells, Cultured, Endocytosis, Endosomes, JNK Mitogen-Activated Protein Kinases, Mice, Inbred C57BL, Mice, Knockout, Mitogen-Activated Protein Kinases, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, NADH, NADPH Oxidoreductases, NADPH Oxidase 1, NF-kappa B, Reactive Oxygen Species, Receptors, Tumor Necrosis Factor, Type I, Receptors, Tumor Necrosis Factor, Type II, Signal Transduction, Tumor Necrosis Factor-alpha
Added July 28, 2015
0 Communities
2 Members
0 Resources
18 MeSH Terms
Knock, knock: who's there?: Nox1.
Itani HA, Dikalov S, Harrison DG
(2013) Circulation 127: 1850-2
MeSH Terms: Animals, Atherosclerosis, Diabetes Mellitus, Experimental, Humans, Male, NADH, NADPH Oxidoreductases, NADPH Oxidase 1, NADPH Oxidases
Added March 31, 2015
1 Communities
3 Members
0 Resources
8 MeSH Terms
A critical role for chloride channel-3 (CIC-3) in smooth muscle cell activation and neointima formation.
Chu X, Filali M, Stanic B, Takapoo M, Sheehan A, Bhalla R, Lamb FS, Miller FJ
(2011) Arterioscler Thromb Vasc Biol 31: 345-51
MeSH Terms: Animals, Cell Proliferation, Cells, Cultured, Chloride Channels, Endosomes, Hyperplasia, Matrix Metalloproteinase 9, Mice, Mice, Knockout, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Models, Animal, Muscle, Smooth, Vascular, NADH, NADPH Oxidoreductases, NADPH Oxidase 1, Neointima, Signal Transduction, Tumor Necrosis Factor-alpha
Added February 22, 2016
0 Communities
1 Members
0 Resources
18 MeSH Terms
Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling.
Dikalova AE, Góngora MC, Harrison DG, Lambeth JD, Dikalov S, Griendling KK
(2010) Am J Physiol Heart Circ Physiol 299: H673-9
MeSH Terms: Analysis of Variance, Angiotensin II, Animals, Blood Pressure, Blotting, Western, Endothelium, Vascular, Hydrogen Peroxide, Hypertension, Mice, Mice, Transgenic, Muscle, Smooth, Vascular, NADH, NADPH Oxidoreductases, NADPH Oxidase 1, NG-Nitroarginine Methyl Ester, Nitric Oxide, Nitric Oxide Synthase Type III, Polymerase Chain Reaction, Up-Regulation, Vasodilation
Added December 10, 2013
1 Communities
2 Members
0 Resources
19 MeSH Terms
NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets.
Dennis KE, Aschner JL, Milatovic D, Schmidt JW, Aschner M, Kaplowitz MR, Zhang Y, Fike CD
(2009) Am J Physiol Lung Cell Mol Physiol 297: L596-607
MeSH Terms: Animals, Animals, Newborn, Antioxidants, Catalase, F2-Isoprostanes, Hypertension, Pulmonary, Hypoxia, Immunoblotting, Luminescence, Manganese, NADPH Oxidase 1, NADPH Oxidases, Organometallic Compounds, Phosphoproteins, Pulmonary Artery, Reactive Oxygen Species, Superoxide Dismutase, Superoxide Dismutase-1, Swine, Vascular Resistance
Added April 7, 2010
0 Communities
2 Members
0 Resources
20 MeSH Terms
Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production.
Dikalov SI, Dikalova AE, Bikineyeva AT, Schmidt HH, Harrison DG, Griendling KK
(2008) Free Radic Biol Med 45: 1340-51
MeSH Terms: Angiotensin II, Animals, Cell Membrane, Electron Spin Resonance Spectroscopy, Free Radicals, Gene Silencing, Hydrogen Peroxide, Models, Biological, Models, Chemical, NADH, NADPH Oxidoreductases, NADPH Oxidase 1, NADPH Oxidase 4, NADPH Oxidases, Oxygen, Rats, Signal Transduction, Superoxides
Added July 20, 2014
0 Communities
2 Members
0 Resources
17 MeSH Terms
Role of extracellular superoxide dismutase in hypertension.
Gongora MC, Qin Z, Laude K, Kim HW, McCann L, Folz JR, Dikalov S, Fukai T, Harrison DG
(2006) Hypertension 48: 473-81
MeSH Terms: Angiotensin II, Animals, Aorta, Blood Pressure, Hypertension, Isoenzymes, Mesenteric Arteries, Mice, Mice, Inbred C57BL, Mice, Knockout, NADH, NADPH Oxidoreductases, NADPH Oxidase 1, NADPH Oxidases, Nitric Oxide, Nitric Oxide Synthase Type III, Superoxide Dismutase, Superoxides, Vasoconstrictor Agents, Vasodilation, Vasomotor System
Added February 17, 2016
0 Communities
1 Members
0 Resources
20 MeSH Terms