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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 17

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α₁-Adrenergic receptors contribute to the acute effects of 3,4-methylenedioxymethamphetamine in humans.
Hysek CM, Fink AE, Simmler LD, Donzelli M, Grouzmann E, Liechti ME
(2013) J Clin Psychopharmacol 33: 658-66
MeSH Terms: Adrenergic alpha-1 Receptor Antagonists, Adult, Affect, Blood Pressure, Body Temperature, Cross-Over Studies, Double-Blind Method, Doxazosin, Drug Interactions, Epinephrine, Female, Healthy Volunteers, Heart Rate, Humans, Male, N-Methyl-3,4-methylenedioxyamphetamine, Norepinephrine, Receptors, Adrenergic, alpha-1, Switzerland, Young Adult
Added August 3, 2013
0 Communities
1 Members
0 Resources
20 MeSH Terms
Human ecstasy (MDMA) polydrug users have altered brain activation during semantic processing.
Watkins TJ, Raj V, Lee J, Dietrich MS, Cao A, Blackford JU, Salomon RM, Park S, Benningfield MM, Di Iorio CR, Cowan RL
(2013) Psychopharmacology (Berl) 227: 41-54
MeSH Terms: Adolescent, Adult, Brain, Female, Humans, Illicit Drugs, Magnetic Resonance Imaging, Male, Memory, N-Methyl-3,4-methylenedioxyamphetamine, Prospective Studies, Psychomotor Performance, Semantics, Young Adult
Added July 28, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Duloxetine inhibits effects of MDMA ("ecstasy") in vitro and in humans in a randomized placebo-controlled laboratory study.
Hysek CM, Simmler LD, Nicola VG, Vischer N, Donzelli M, Krähenbühl S, Grouzmann E, Huwyler J, Hoener MC, Liechti ME
(2012) PLoS One 7: e36476
MeSH Terms: 3,4-Methylenedioxyamphetamine, Adult, Biological Transport, Duloxetine Hydrochloride, Female, Humans, Laboratories, Male, N-Methyl-3,4-methylenedioxyamphetamine, Norepinephrine, Placebo Effect, Receptors, Adrenergic, Serotonin, Serotonin Plasma Membrane Transport Proteins, Thiophenes
Added August 3, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms
Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans.
Hysek C, Schmid Y, Rickli A, Simmler LD, Donzelli M, Grouzmann E, Liechti ME
(2012) Br J Pharmacol 166: 2277-88
MeSH Terms: Adrenergic Antagonists, Adult, Area Under Curve, Body Temperature, Carbazoles, Carvedilol, Catecholamines, Cross-Over Studies, Drug Interactions, Female, Heart Rate, Humans, Male, N-Methyl-3,4-methylenedioxyamphetamine, Propanolamines, Young Adult
Added August 3, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Effects of the α₂-adrenergic agonist clonidine on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine in healthy volunteers.
Hysek CM, Brugger R, Simmler LD, Bruggisser M, Donzelli M, Grouzmann E, Hoener MC, Liechti ME
(2012) J Pharmacol Exp Ther 340: 286-94
MeSH Terms: 3,4-Methylenedioxyamphetamine, Adrenergic alpha-2 Receptor Agonists, Adult, Affect, Blood Pressure, Body Temperature, Brain, Clonidine, Consciousness, Cross-Over Studies, Double-Blind Method, Drug Interactions, Emotions, Epinephrine, Female, Heart Rate, Humans, Male, Mental Processes, N-Methyl-3,4-methylenedioxyamphetamine, Norepinephrine, Young Adult
Added August 3, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
Sex differences in the effects of MDMA (ecstasy) on plasma copeptin in healthy subjects.
Simmler LD, Hysek CM, Liechti ME
(2011) J Clin Endocrinol Metab 96: 2844-50
MeSH Terms: Adult, Arginine Vasopressin, Cross-Over Studies, Duloxetine Hydrochloride, Female, Glycopeptides, Humans, Male, N-Methyl-3,4-methylenedioxyamphetamine, Osmolar Concentration, Serotonin Agents, Serotonin Uptake Inhibitors, Sex Characteristics, Thiophenes
Added August 3, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
The norepinephrine transporter inhibitor reboxetine reduces stimulant effects of MDMA ("ecstasy") in humans.
Hysek CM, Simmler LD, Ineichen M, Grouzmann E, Hoener MC, Brenneisen R, Huwyler J, Liechti ME
(2011) Clin Pharmacol Ther 90: 246-55
MeSH Terms: 3,4-Methylenedioxyamphetamine, Adrenergic Uptake Inhibitors, Adult, Blood Pressure, Cross-Over Studies, Double-Blind Method, Drug Interactions, Female, Hallucinogens, Heart Rate, Humans, Male, Morpholines, N-Methyl-3,4-methylenedioxyamphetamine, Norepinephrine, Norepinephrine Plasma Membrane Transport Proteins, Reboxetine, Young Adult
Added August 3, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
Human Ecstasy use is associated with increased cortical excitability: an fMRI study.
Bauernfeind AL, Dietrich MS, Blackford JU, Charboneau EJ, Lillevig JG, Cannistraci CJ, Woodward ND, Cao A, Watkins T, Di Iorio CR, Cascio C, Salomon RM, Cowan RL
(2011) Neuropsychopharmacology 36: 1127-41
MeSH Terms: Adolescent, Adult, Brain, Brain Mapping, Cerebrovascular Circulation, Female, Geniculate Bodies, Humans, Magnetic Resonance Imaging, Male, N-Methyl-3,4-methylenedioxyamphetamine, Serotonin Agents, Visual Cortex, Visual Pathways, Young Adult
Added February 15, 2016
0 Communities
2 Members
0 Resources
15 MeSH Terms
Transmembrane domain 6 of the human serotonin transporter contributes to an aqueously accessible binding pocket for serotonin and the psychostimulant 3,4-methylene dioxymethamphetamine.
Field JR, Henry LK, Blakely RD
(2010) J Biol Chem 285: 11270-80
MeSH Terms: Biological Transport, Cytoplasm, Humans, Kinetics, Models, Biological, Mutagenesis, Site-Directed, Mutation, N-Methyl-3,4-methylenedioxyamphetamine, Protein Binding, Protein Conformation, Protein Structure, Tertiary, Serotonin, Serotonin Agents, Serotonin Plasma Membrane Transport Proteins, Water
Added July 10, 2013
1 Communities
1 Members
0 Resources
15 MeSH Terms
Drugs, biogenic amine targets and the developing brain.
Frederick AL, Stanwood GD
(2009) Dev Neurosci 31: 7-22
MeSH Terms: Adult, Amphetamine-Related Disorders, Animals, Behavior, Biogenic Amines, Brain, Brain Chemistry, Child, Child Development, Cocaine-Related Disorders, Environmental Pollutants, Female, Humans, N-Methyl-3,4-methylenedioxyamphetamine, Pregnancy, Psychotropic Drugs, Substance-Related Disorders, Toxins, Biological
Added January 20, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms