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Results: 1 to 8 of 8

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Familial hypertrophic cardiomyopathy: is the Frank-Starling law kaput?
Huke S, Knollmann BC
(2013) Circ Res 112: 1409-11
MeSH Terms: Animals, Cardiomyopathy, Hypertrophic, Female, Humans, Male, Myofibrils, Sarcomeres
Added May 27, 2014
0 Communities
2 Members
0 Resources
7 MeSH Terms
Myofilament calcium de-sensitization and contractile uncoupling prevent pause-triggered ventricular tachycardia in mouse hearts with chronic myocardial infarction.
Venkataraman R, Baldo MP, Hwang HS, Veltri T, Pinto JR, Baudenbacher FJ, Knollmann BC
(2013) J Mol Cell Cardiol 60: 8-15
MeSH Terms: Animals, Calcium, Chronic Disease, Disease Models, Animal, Heterocyclic Compounds, 4 or More Rings, Male, Mice, Myocardial Contraction, Myocardial Infarction, Myocardium, Myofibrils, Tachycardia, Ventricular
Added February 12, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Focal energy deprivation underlies arrhythmia susceptibility in mice with calcium-sensitized myofilaments.
Huke S, Venkataraman R, Faggioni M, Bennuri S, Hwang HS, Baudenbacher F, Knollmann BC
(2013) Circ Res 112: 1334-44
MeSH Terms: Adenosine Triphosphate, Adenylate Kinase, Animals, Arrhythmias, Cardiac, Calcium, Cardiomyopathy, Hypertrophic, Cardiotonic Agents, Connexin 43, Disease Models, Animal, Disease Susceptibility, Electrocardiography, Energy Metabolism, Female, Gap Junctions, Heterocyclic Compounds, 4 or More Rings, Male, Mice, Mice, Inbred Strains, Mice, Transgenic, Myofibrils, Quinolines, Thiadiazines
Added May 27, 2014
0 Communities
2 Members
0 Resources
22 MeSH Terms
Myofilament Ca sensitization increases cytosolic Ca binding affinity, alters intracellular Ca homeostasis, and causes pause-dependent Ca-triggered arrhythmia.
Schober T, Huke S, Venkataraman R, Gryshchenko O, Kryshtal D, Hwang HS, Baudenbacher FJ, Knollmann BC
(2012) Circ Res 111: 170-9
MeSH Terms: Action Potentials, Animals, Arrhythmias, Cardiac, Calcium, Calcium Signaling, Cytosol, Homeostasis, Humans, Intracellular Fluid, Mice, Mice, Transgenic, Mutation, Myofibrils, Protein Binding, Up-Regulation
Added May 27, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Goodpasture antigen-binding protein (GPBP) directs myofibril formation: identification of intracellular downstream effector 130-kDa GPBP-interacting protein (GIP130).
Revert-Ros F, López-Pascual E, Granero-Moltó F, Macías J, Breyer R, Zent R, Hudson BG, Saadeddin A, Revert F, Blasco R, Navarro C, Burks D, Saus J
(2011) J Biol Chem 286: 35030-43
MeSH Terms: Animals, Basement Membrane, Blood Proteins, Carrier Proteins, Cell Line, Collagen, DNA-Binding Proteins, Gene Expression Regulation, Intracellular Signaling Peptides and Proteins, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Myoblasts, Myofibrils, Phosphorylation, Protein-Serine-Threonine Kinases, Recombinant Proteins
Added February 25, 2014
2 Communities
3 Members
0 Resources
19 MeSH Terms
Body composition and energy metabolism following Roux-en-Y gastric bypass surgery.
Tamboli RA, Hossain HA, Marks PA, Eckhauser AW, Rathmacher JA, Phillips SE, Buchowski MS, Chen KY, Abumrad NN
(2010) Obesity (Silver Spring) 18: 1718-24
MeSH Terms: Adipose Tissue, Adolescent, Adult, Aged, Body Composition, Body Fluid Compartments, Energy Metabolism, Female, Gastric Bypass, Humans, Longitudinal Studies, Male, Methylhistidines, Middle Aged, Muscle Proteins, Myofibrils, Obesity, Morbid, Radiography, Weight Loss, Young Adult
Added December 10, 2013
0 Communities
2 Members
1 Resources
20 MeSH Terms
Antioxidant supplementation had positive effects in old rat muscle, but through better oxidative status in other organs.
Mosoni L, Balage M, Vazeille E, Combaret L, Morand C, Zagol-Ikapitte I, Boutaud O, Marzani B, Papet I, Dardevet D
(2010) Nutrition 26: 1157-62
MeSH Terms: Aging, Animals, Antioxidants, Cathepsins, Dietary Supplements, Glutathione, Liver, Male, Muscle, Skeletal, Myocardium, Myofibrils, Oxidation-Reduction, Oxidative Stress, Peptide Hydrolases, Protein Carbonylation, Rats, Rats, Wistar, Spleen, Superoxide Dismutase, Thiobarbituric Acid Reactive Substances
Added March 27, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Inhibition of ErbB2 by receptor tyrosine kinase inhibitors causes myofibrillar structural damage without cell death in adult rat cardiomyocytes.
Pentassuglia L, Graf M, Lane H, Kuramochi Y, Cote G, Timolati F, Sawyer DB, Zuppinger C, Suter TM
(2009) Exp Cell Res 315: 1302-12
MeSH Terms: Animals, Antibiotics, Antineoplastic, Calcium, Cell Death, Cells, Cultured, Connectin, Doxorubicin, ErbB Receptors, Extracellular Signal-Regulated MAP Kinases, Female, GATA4 Transcription Factor, Male, Mice, Mitochondria, Muscle Proteins, Myocardial Contraction, Myocytes, Cardiac, Myofibrils, Protein Kinase Inhibitors, Proto-Oncogene Proteins c-akt, Rats, Rats, Wistar, Receptor, ErbB-2, Receptor, ErbB-4, Signal Transduction
Added May 21, 2014
1 Communities
1 Members
0 Resources
25 MeSH Terms