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Bone Marrow-Derived Proangiogenic Cells Mediate Pulmonary Arteriole Stiffening via Serotonin 2B Receptor Dependent Mechanism.
Bloodworth NC, Clark CR, West JD, Snider JC, Gaskill C, Shay S, Scott C, Bastarache J, Gladson S, Moore C, D'Amico R, Brittain EL, Tanjore H, Blackwell TS, Majka SM, Merryman WD
(2018) Circ Res 123: e51-e64
MeSH Terms: Angiogenesis Inhibitors, Animals, Arterioles, Cell Lineage, Cells, Cultured, Hypertension, Pulmonary, Indoles, Lung, Mice, Mice, Inbred C57BL, Myeloid Progenitor Cells, Pyrroles, Receptor, Serotonin, 5-HT2B, Vascular Stiffness
Added April 2, 2019
0 Communities
1 Members
0 Resources
14 MeSH Terms
Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study.
Salisbury-Ruf CT, Bertram CC, Vergeade A, Lark DS, Shi Q, Heberling ML, Fortune NL, Okoye GD, Jerome WG, Wells QS, Fessel J, Moslehi J, Chen H, Roberts LJ, Boutaud O, Gamazon ER, Zinkel SS
(2018) Elife 7:
MeSH Terms: Animals, Apoptosis, BH3 Interacting Domain Death Agonist Protein, Beclin-1, Cell Respiration, Fibrosis, Gene Expression Regulation, Genome-Wide Association Study, Genomics, Heart Diseases, Heart Ventricles, Humans, Mice, Inbred C57BL, Mitochondria, Mitochondrial Proton-Translocating ATPases, Mutation, Myeloid Progenitor Cells, Myocardial Infarction, Myocytes, Cardiac, Polymorphism, Single Nucleotide, Protein Multimerization, Protein Structure, Secondary, Protein Subunits, Reactive Oxygen Species, Reproducibility of Results, Up-Regulation
Added December 11, 2018
0 Communities
4 Members
0 Resources
26 MeSH Terms
Early TGF-β inhibition in mice reduces the incidence of breast cancer induced bone disease in a myeloid dependent manner.
Buenrostro D, Kwakwa KA, Putnam NE, Merkel AR, Johnson JR, Cassat JE, Sterling JA
(2018) Bone 113: 77-88
MeSH Terms: Animals, Bone Neoplasms, Female, Humans, Mammary Neoplasms, Experimental, Mice, Mice, Knockout, Myeloid Progenitor Cells, Transforming Growth Factor beta, Tumor Microenvironment
Added April 15, 2019
0 Communities
2 Members
0 Resources
10 MeSH Terms
Cardiolipin fatty acid remodeling regulates mitochondrial function by modifying the electron entry point in the respiratory chain.
Vergeade A, Bertram CC, Bikineyeva AT, Zackert WE, Zinkel SS, May JM, Dikalov SI, Roberts LJ, Boutaud O
(2016) Mitochondrion 28: 88-95
MeSH Terms: Acetaminophen, Antipyretics, Cardiolipins, Cell Respiration, Cells, Cultured, Electron Transport, Fatty Acids, Humans, Mitochondria, Myeloid Progenitor Cells, Quinones
Added April 25, 2016
0 Communities
2 Members
0 Resources
11 MeSH Terms
Bid protects the mouse hematopoietic system following hydroxyurea-induced replicative stress.
Liu Y, Aiello A, Zinkel SS
(2012) Cell Death Differ 19: 1602-12
MeSH Terms: Animals, Antigens, Ly, Antineoplastic Agents, Apoptosis, Ataxia Telangiectasia Mutated Proteins, BH3 Interacting Domain Death Agonist Protein, Cell Cycle Proteins, DNA Repair, Hematopoietic Stem Cell Transplantation, Hematopoietic Stem Cells, Hydroxyurea, Membrane Proteins, Methylcellulose, Mice, Mice, Inbred C57BL, Mice, Knockout, Myeloid Progenitor Cells, Nucleotidyltransferases, Oxidative Stress, Protein Serine-Threonine Kinases, Proto-Oncogene Proteins c-kit
Added December 5, 2013
1 Communities
1 Members
0 Resources
21 MeSH Terms
Quantitative assessment of myeloid nuclear differentiation antigen distinguishes myelodysplastic syndrome from normal bone marrow.
McClintock-Treep SA, Briggs RC, Shults KE, Flye-Blakemore LA, Mosse CA, Jagasia MH, Shinar AA, Dupont WD, Stelzer GT, Head DR
(2011) Am J Clin Pathol 135: 380-5
MeSH Terms: Adult, Aged, Aged, 80 and over, Antigens, Differentiation, Myelomonocytic, Bone Marrow, Bone Marrow Cells, Child, Preschool, Female, Flow Cytometry, Humans, Male, Middle Aged, Myelodysplastic Syndromes, Myeloid Progenitor Cells, Predictive Value of Tests, Prognosis, ROC Curve, Young Adult
Added March 5, 2014
0 Communities
2 Members
0 Resources
18 MeSH Terms
Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and lineage allocation.
Chyla BJ, Moreno-Miralles I, Steapleton MA, Thompson MA, Bhaskara S, Engel M, Hiebert SW
(2008) Mol Cell Biol 28: 6234-47
MeSH Terms: Anemia, Animals, Antigens, CD34, Bone Marrow Cells, Cell Lineage, Cell Proliferation, Chromosomes, Mammalian, Colony-Forming Units Assay, Female, Gene Deletion, Gene Regulatory Networks, Hematopoietic Stem Cells, Humans, Male, Megakaryocytes, Mice, Multipotent Stem Cells, Myeloid Progenitor Cells, Nuclear Proteins, Phenylhydrazines, Proto-Oncogene Proteins c-kit, Proto-Oncogene Proteins c-myc, Receptors, IgG, Repressor Proteins, Time Factors, Transcription Factors, Translocation, Genetic
Added August 13, 2010
2 Communities
2 Members
0 Resources
27 MeSH Terms
Dysregulated human myeloid nuclear differentiation antigen expression in myelodysplastic syndromes: evidence for a role in apoptosis.
Briggs RC, Shults KE, Flye LA, McClintock-Treep SA, Jagasia MH, Goodman SA, Boulos FI, Jacobberger JW, Stelzer GT, Head DR
(2006) Cancer Res 66: 4645-51
MeSH Terms: Antigens, Differentiation, Myelomonocytic, Apoptosis, Apoptosis Regulatory Proteins, Down-Regulation, HL-60 Cells, Humans, K562 Cells, Membrane Glycoproteins, Myelodysplastic Syndromes, Myeloid Progenitor Cells, TNF-Related Apoptosis-Inducing Ligand, Transcription Factors, Tumor Necrosis Factor-alpha
Added March 5, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
A role for proapoptotic BID in the DNA-damage response.
Zinkel SS, Hurov KE, Ong C, Abtahi FM, Gross A, Korsmeyer SJ
(2005) Cell 122: 579-91
MeSH Terms: Animals, Apoptosis, Ataxia Telangiectasia Mutated Proteins, BH3 Interacting Domain Death Agonist Protein, Carrier Proteins, Cell Cycle Proteins, Cell Line, Transformed, Cell Transformation, Neoplastic, DNA Damage, DNA-Binding Proteins, Female, Genes, cdc, Genomic Instability, Leukemia, Myelomonocytic, Chronic, Male, Mice, Mice, Knockout, Mutagens, Myeloid Progenitor Cells, NIH 3T3 Cells, Phosphorylation, Protein Serine-Threonine Kinases, Protein Structure, Tertiary, S Phase, Tumor Suppressor Proteins
Added September 7, 2011
1 Communities
1 Members
0 Resources
25 MeSH Terms