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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 13

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A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily.
Korkut A, Zaidi S, Kanchi RS, Rao S, Gough NR, Schultz A, Li X, Lorenzi PL, Berger AC, Robertson G, Kwong LN, Datto M, Roszik J, Ling S, Ravikumar V, Manyam G, Rao A, Shelley S, Liu Y, Ju Z, Hansel D, de Velasco G, Pennathur A, Andersen JB, O'Rourke CJ, Ohshiro K, Jogunoori W, Nguyen BN, Li S, Osmanbeyoglu HU, Ajani JA, Mani SA, Houseman A, Wiznerowicz M, Chen J, Gu S, Ma W, Zhang J, Tong P, Cherniack AD, Deng C, Resar L, Cancer Genome Atlas Research Network, Weinstein JN, Mishra L, Akbani R
(2018) Cell Syst 7: 422-437.e7
MeSH Terms: Bone Morphogenetic Protein 5, DNA Methylation, Humans, MicroRNAs, Mutation Rate, Neoplasms, Receptor, Transforming Growth Factor-beta Type I, Signal Transduction, Smad Proteins, Transforming Growth Factor beta
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Genomic and Functional Approaches to Understanding Cancer Aneuploidy.
Taylor AM, Shih J, Ha G, Gao GF, Zhang X, Berger AC, Schumacher SE, Wang C, Hu H, Liu J, Lazar AJ, Cancer Genome Atlas Research Network, Cherniack AD, Beroukhim R, Meyerson M
(2018) Cancer Cell 33: 676-689.e3
MeSH Terms: Aneuploidy, Carcinoma, Squamous Cell, Cell Cycle, Cell Proliferation, Chromosome Aberrations, Chromosome Deletion, Chromosomes, Human, Pair 3, Databases, Genetic, Genomics, Humans, Mutation Rate, Tumor Suppressor Protein p53
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types.
Seiler M, Peng S, Agrawal AA, Palacino J, Teng T, Zhu P, Smith PG, Cancer Genome Atlas Research Network, Buonamici S, Yu L
(2018) Cell Rep 23: 282-296.e4
MeSH Terms: Cell Line, Tumor, Genes, Tumor Suppressor, Humans, Loss of Function Mutation, Mutation Rate, Neoplasms, Oncogenes, RNA Splicing, RNA Splicing Factors
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Bivariate Poisson models with varying offsets: an application to the paired mitochondrial DNA dataset.
Su PF, Mau YL, Guo Y, Li CI, Liu Q, Boice JD, Shyr Y
(2017) Stat Appl Genet Mol Biol 16: 47-58
MeSH Terms: Antineoplastic Agents, Base Sequence, Cancer Survivors, Computer Simulation, DNA, Mitochondrial, Databases, Nucleic Acid, Genome, Mitochondrial, Humans, Models, Biological, Mutation Rate, Regression Analysis
Added April 18, 2017
0 Communities
1 Members
0 Resources
11 MeSH Terms
DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cells.
Bose A, Pande P, Jasti VP, Millsap AD, Hawkins EK, Rizzo CJ, Basu AK
(2015) Nucleic Acids Res 43: 8340-51
MeSH Terms: DNA, DNA Adducts, DNA-Directed DNA Polymerase, Deoxyguanosine, HEK293 Cells, Humans, Mutagens, Mutation Rate, Quinolines
Added January 7, 2016
0 Communities
1 Members
0 Resources
9 MeSH Terms
Tissue-specific expressed antibody variable gene repertoires.
Briney BS, Willis JR, Finn JA, McKinney BA, Crowe JE
(2014) PLoS One 9: e100839
MeSH Terms: Adolescent, Adult, Antibodies, Bone Marrow, Cluster Analysis, Complementarity Determining Regions, DNA, Demography, Gene Expression Regulation, Germ Cells, High-Throughput Nucleotide Sequencing, Humans, Immunoglobulin Variable Region, Lymphoid Tissue, Middle Aged, Mucous Membrane, Mutation, Mutation Rate, Organ Specificity, RNA, Somatic Hypermutation, Immunoglobulin, V(D)J Recombination, Young Adult
Added February 2, 2015
0 Communities
1 Members
0 Resources
23 MeSH Terms
In vivo roles of conjugation with glutathione and O6-alkylguanine DNA-alkyltransferase in the mutagenicity of the bis-electrophiles 1,2-dibromoethane and 1,2,3,4-diepoxybutane in mice.
Cho SH, Guengerich FP
(2013) Chem Res Toxicol 26: 1765-74
MeSH Terms: Animals, Butadienes, Buthionine Sulfoximine, Chromatography, High Pressure Liquid, DNA Adducts, DNA Mutational Analysis, Epoxy Compounds, Ethylene Dibromide, Glutathione, Glutathione Transferase, Guanine, Liver, Male, Mice, Mice, Transgenic, Mutagenicity Tests, Mutation, Mutation Rate, O(6)-Methylguanine-DNA Methyltransferase, Spectrometry, Mass, Electrospray Ionization
Added March 7, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Pif1 family helicases suppress genome instability at G-quadruplex motifs.
Paeschke K, Bochman ML, Garcia PD, Cejka P, Friedman KL, Kowalczykowski SC, Zakian VA
(2013) Nature 497: 458-62
MeSH Terms: Base Sequence, Conserved Sequence, DNA Damage, DNA Helicases, Epigenesis, Genetic, Evolution, Molecular, G-Quadruplexes, Gene Silencing, Genetic Complementation Test, Genomic Instability, Humans, Molecular Sequence Data, Mutation Rate, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Telomere Homeostasis
Added March 7, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma.
Green MR, Gentles AJ, Nair RV, Irish JM, Kihira S, Liu CL, Kela I, Hopmans ES, Myklebust JH, Ji H, Plevritis SK, Levy R, Alizadeh AA
(2013) Blood 121: 1604-11
MeSH Terms: Clonal Evolution, Clone Cells, DNA, Neoplasm, Disease Progression, Exome, Gene Frequency, Genome, Human, High-Throughput Nucleotide Sequencing, Humans, Immunophenotyping, Lymphoma, Follicular, Mutation, Mutation Rate, Polymerase Chain Reaction, Recurrence
Added February 15, 2013
1 Communities
1 Members
0 Resources
15 MeSH Terms
Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing.
Imielinski M, Berger AH, Hammerman PS, Hernandez B, Pugh TJ, Hodis E, Cho J, Suh J, Capelletti M, Sivachenko A, Sougnez C, Auclair D, Lawrence MS, Stojanov P, Cibulskis K, Choi K, de Waal L, Sharifnia T, Brooks A, Greulich H, Banerji S, Zander T, Seidel D, Leenders F, Ansén S, Ludwig C, Engel-Riedel W, Stoelben E, Wolf J, Goparju C, Thompson K, Winckler W, Kwiatkowski D, Johnson BE, Jänne PA, Miller VA, Pao W, Travis WD, Pass HI, Gabriel SB, Lander ES, Thomas RK, Garraway LA, Getz G, Meyerson M
(2012) Cell 150: 1107-20
MeSH Terms: Adenocarcinoma, Adenocarcinoma of Lung, Adult, Aged, Aged, 80 and over, Carcinoma, Non-Small-Cell Lung, Cohort Studies, Exome, Female, Genes, Neoplasm, Genome-Wide Association Study, High-Throughput Nucleotide Sequencing, Humans, Lung Neoplasms, Male, Middle Aged, Mutation, Mutation Rate
Added September 3, 2013
0 Communities
2 Members
0 Resources
18 MeSH Terms