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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 96

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Mechanisms of mutagenesis: DNA replication in the presence of DNA damage.
Liu B, Xue Q, Tang Y, Cao J, Guengerich FP, Zhang H
(2016) Mutat Res Rev Mutat Res 768: 53-67
MeSH Terms: Animals, DNA Adducts, DNA Damage, DNA Repair, DNA Replication, DNA-Directed DNA Polymerase, Environmental Exposure, Genetic Predisposition to Disease, Humans, Mutagenesis, Mutagens, Mutation, Protein Binding
Added March 14, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cells.
Bose A, Pande P, Jasti VP, Millsap AD, Hawkins EK, Rizzo CJ, Basu AK
(2015) Nucleic Acids Res 43: 8340-51
MeSH Terms: DNA, DNA Adducts, DNA-Directed DNA Polymerase, Deoxyguanosine, HEK293 Cells, Humans, Mutagens, Mutation Rate, Quinolines
Added January 7, 2016
0 Communities
1 Members
0 Resources
9 MeSH Terms
Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells.
Carrillo AM, Hicks M, Khabele D, Eischen CM
(2015) Mol Cancer Res 13: 1197-205
MeSH Terms: Animals, Antineoplastic Combined Chemotherapy Protocols, Apoptosis, Cell Line, Tumor, Cell Proliferation, Cisplatin, Comet Assay, DNA Breaks, Double-Stranded, DNA Damage, DNA Repair, Etoposide, Female, Fibroblasts, HEK293 Cells, Humans, Imidazoles, Mice, Mice, Transgenic, Mutagens, Ovarian Neoplasms, Piperazines, Proto-Oncogene Proteins c-mdm2, Tumor Suppressor Protein p53
Added February 22, 2016
0 Communities
1 Members
0 Resources
23 MeSH Terms
GRASr2 evaluation of aliphatic acyclic and alicyclic terpenoid tertiary alcohols and structurally related substances used as flavoring ingredients.
Marnett LJ, Cohen SM, Fukushima S, Gooderham NJ, Hecht SS, Rietjens IM, Smith RL, Adams TB, Bastaki M, Harman CL, McGowen MM, Taylor SV
(2014) J Food Sci 79: R428-41
MeSH Terms: Alcohols, Animals, Diet, Flavoring Agents, Food Industry, Humans, Mutagens, No-Observed-Adverse-Effect Level, Safety, Terpenes, Toxicity Tests
Added June 1, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Replication, repair, and translesion polymerase bypass of N⁶-oxopropenyl-2'-deoxyadenosine.
Maddukuri L, Shuck SC, Eoff RL, Zhao L, Rizzo CJ, Guengerich FP, Marnett LJ
(2013) Biochemistry 52: 8766-76
MeSH Terms: DNA Polymerase I, DNA Repair, DNA Replication, DNA-Directed DNA Polymerase, Deoxyadenosines, Humans, Kinetics, Mutagenicity Tests, Mutagens, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
3 Members
0 Resources
10 MeSH Terms
Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics.
Smith EC, Blanc H, Surdel MC, Vignuzzi M, Denison MR
(2013) PLoS Pathog 9: e1003565
MeSH Terms: Animals, Antiviral Agents, Apoptosis, Astrocytoma, Brain Neoplasms, Cell Proliferation, Coronavirus, Coronavirus Infections, Exoribonucleases, Genome, Viral, Humans, Mice, Mutagenesis, Mutagens, Mutation, RNA, Messenger, RNA, Viral, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Tumor Cells, Cultured, Viral Proteins, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
22 MeSH Terms
Sequence context modulation of polycyclic aromatic hydrocarbon-induced mutagenesis.
Chary P, Stone MP, Lloyd RS
(2013) Environ Mol Mutagen 54: 652-8
MeSH Terms: Base Pair Mismatch, DNA Adducts, DNA Polymerase I, DNA-Directed DNA Polymerase, Escherichia coli, Molecular Structure, Mutagenesis, Mutagens, Polycyclic Aromatic Hydrocarbons, Stereoisomerism
Added March 7, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Conditional control of gene function by an invertible gene trap in zebrafish.
Ni TT, Lu J, Zhu M, Maddison LA, Boyd KL, Huskey L, Ju B, Hesselson D, Zhong TP, Page-McCaw PS, Stainier DY, Chen W
(2012) Proc Natl Acad Sci U S A 109: 15389-94
MeSH Terms: Alleles, Animals, DNA Nucleotidyltransferases, DNA Transposable Elements, Hepatocytes, Integrases, Liver, Mitochondria, Models, Genetic, Mutagenesis, Mutagens, Mutation, Phenotype, Polymerase Chain Reaction, RNA Helicases, Recombination, Genetic, Zebrafish
Added January 7, 2014
1 Communities
3 Members
0 Resources
17 MeSH Terms
Meat consumption, cooking methods, mutagens, and risk of squamous cell carcinoma of the esophagus: a case-control study in Uruguay.
De Stefani E, Deneo-Pellegrini H, Ronco AL, Boffetta P, Correa P, Aune D, Mendilaharsu M, Acosta G, Silva C, Landó G, Luaces ME
(2012) Nutr Cancer 64: 294-9
MeSH Terms: Adult, Aged, Aged, 80 and over, Animals, Carcinoma, Squamous Cell, Case-Control Studies, Cooking, Diet, Esophageal Neoplasms, Female, Humans, Male, Meat, Middle Aged, Mutagens, Odds Ratio, Risk Factors, Uruguay
Added September 3, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
Conjugation of butadiene diepoxide with glutathione yields DNA adducts in vitro and in vivo.
Cho SH, Guengerich FP
(2012) Chem Res Toxicol 25: 706-12
MeSH Terms: Animals, Cross-Linking Reagents, DNA Adducts, Epoxy Compounds, Glutathione, Liver, Mice, Mutagenicity Tests, Mutagens, Rats, Rats, Sprague-Dawley, Salmonella typhi
Added March 7, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms