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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 48

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In vitro safety pharmacology evaluation of 2-hydroxybenzylamine acetate.
Fuller JC, Pitchford LM, Morrison RD, Daniels JS, Flynn CR, Abumrad NN, Oates JA, Boutaud O, Rathmacher JA
(2018) Food Chem Toxicol 121: 541-548
MeSH Terms: Adult, Benzylamines, Blood Proteins, Cytochrome P-450 Enzyme System, ERG1 Potassium Channel, Erythrocytes, Female, Gene Expression Regulation, Enzymologic, Hepatocytes, Humans, Male, Middle Aged, Mutagenicity Tests, Salmonella typhimurium
Added April 15, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
FEMA expert panel review of p-mentha-1,8-dien-7-al genotoxicity testing results.
Cohen SM, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IMCM, Smith RL, Bastaki M, Harman CL, McGowen MM, Taylor SV
(2016) Food Chem Toxicol 98: 201-209
MeSH Terms: Animals, DNA Damage, Legislation, Food, Micronucleus Tests, Monoterpenes, Mutagenicity Tests, Perilla, Rats
Added March 14, 2018
0 Communities
1 Members
0 Resources
8 MeSH Terms
In vivo roles of conjugation with glutathione and O6-alkylguanine DNA-alkyltransferase in the mutagenicity of the bis-electrophiles 1,2-dibromoethane and 1,2,3,4-diepoxybutane in mice.
Cho SH, Guengerich FP
(2013) Chem Res Toxicol 26: 1765-74
MeSH Terms: Animals, Butadienes, Buthionine Sulfoximine, Chromatography, High Pressure Liquid, DNA Adducts, DNA Mutational Analysis, Epoxy Compounds, Ethylene Dibromide, Glutathione, Glutathione Transferase, Guanine, Liver, Male, Mice, Mice, Transgenic, Mutagenicity Tests, Mutation, Mutation Rate, O(6)-Methylguanine-DNA Methyltransferase, Spectrometry, Mass, Electrospray Ionization
Added March 7, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Safety assessment of borosilicate glasses as used in cosmetics.
Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Andersen FA
(2013) Int J Toxicol 32: 65S-72S
MeSH Terms: Animals, Boron Compounds, Consumer Product Safety, Cosmetics, Glass, Humans, Mutagenicity Tests, Silicates, Skin
Added March 20, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Safety assessment of bis-diglyceryl polyacyladipate-2 and bis-diglyceryl polyacyladipate-1 as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Andersen FA
(2013) Int J Toxicol 32: 56S-64S
MeSH Terms: Adipates, Animals, Consumer Product Safety, Cosmetics, Emollients, Humans, Mutagenicity Tests, Skin
Added March 20, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Safety assessment of lauriminodipropionic acid, sodium lauriminodipropionate, and disodium lauriminodipropionate as used in cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler D, Marks JG, Shank RC, Slaga TJ, Snyder PW, Andersen FA
(2013) Int J Toxicol 32: 49S-55S
MeSH Terms: Animals, Consumer Product Safety, Cosmetics, Humans, Imidoesters, Mutagenicity Tests, Reproduction, Skin, Surface-Active Agents
Added March 20, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Safety assessment of decyl glucoside and other alkyl glucosides as used in cosmetics.
Fiume MM, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler D, Marks JG, Shank RC, Slaga TJ, Snyder PW, Andersen FA
(2013) Int J Toxicol 32: 22S-48S
MeSH Terms: Animals, Consumer Product Safety, Cosmetics, Glucosides, Humans, Mutagenicity Tests, Reproduction, Skin
Added March 20, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Replication, repair, and translesion polymerase bypass of N⁶-oxopropenyl-2'-deoxyadenosine.
Maddukuri L, Shuck SC, Eoff RL, Zhao L, Rizzo CJ, Guengerich FP, Marnett LJ
(2013) Biochemistry 52: 8766-76
MeSH Terms: DNA Polymerase I, DNA Repair, DNA Replication, DNA-Directed DNA Polymerase, Deoxyadenosines, Humans, Kinetics, Mutagenicity Tests, Mutagens, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
3 Members
0 Resources
10 MeSH Terms
Mutagenic spectra arising from replication bypass of the 2,6-diamino-4-hydroxy-N(5)-methyl formamidopyrimidine adduct in primate cells.
Earley LF, Minko IG, Christov PP, Rizzo CJ, Lloyd RS
(2013) Chem Res Toxicol 26: 1108-14
MeSH Terms: Animals, Base Sequence, COS Cells, Chlorocebus aethiops, DNA Adducts, DNA Replication, Mutagenesis, Mutagenicity Tests, Pyrimidines
Added March 7, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Mutation spectra of S-(2-hydroxy-3,4-epoxybutyl)glutathione: comparison with 1,3-butadiene and its metabolites in the Escherichia coli rpoB gene.
Cho SH, Guengerich FP
(2012) Chem Res Toxicol 25: 1522-30
MeSH Terms: Animals, Butadienes, Cell Survival, Chromatography, High Pressure Liquid, DNA, DNA Adducts, DNA-Directed RNA Polymerases, Epoxy Compounds, Escherichia coli, Escherichia coli Proteins, Glutathione, Glutathione Transferase, Mice, Microsomes, Liver, Mutagenicity Tests, Mutation, Rats, Tandem Mass Spectrometry
Added March 7, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms