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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 47

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Serotonin Receptor Agonist 5-Nonyloxytryptamine Alters the Kinetics of Reovirus Cell Entry.
Mainou BA, Ashbrook AW, Smith EC, Dorset DC, Denison MR, Dermody TS
(2015) J Virol 89: 8701-12
MeSH Terms: Animals, Antiviral Agents, Biological Transport, Cell Line, Cell Survival, Chikungunya virus, Chlorocebus aethiops, Cholera Toxin, Cricetinae, Cytoskeleton, Endosomes, HeLa Cells, Humans, Interferon-gamma, L Cells, Methiothepin, Mice, Murine hepatitis virus, Reoviridae, Reoviridae Infections, Serotonin Antagonists, Transferrin, Tryptamines, Vero Cells, Virus Assembly, Virus Attachment, Virus Internalization
Added February 4, 2016
0 Communities
1 Members
0 Resources
27 MeSH Terms
Mutations across murine hepatitis virus nsp4 alter virus fitness and membrane modifications.
Beachboard DC, Anderson-Daniels JM, Denison MR
(2015) J Virol 89: 2080-9
MeSH Terms: Cell Membrane, DNA Mutational Analysis, Glycosylation, Murine hepatitis virus, Mutation, Missense, RNA, Viral, Viral Nonstructural Proteins, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
8 MeSH Terms
Coronavirus replicase-reporter fusions provide quantitative analysis of replication and replication complex formation.
Freeman MC, Graham RL, Lu X, Peek CT, Denison MR
(2014) J Virol 88: 5319-27
MeSH Terms: Animals, Artificial Gene Fusion, Cell Line, Genes, Reporter, Green Fluorescent Proteins, Murine hepatitis virus, RNA-Dependent RNA Polymerase, Recombinant Fusion Proteins, Staining and Labeling, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
10 MeSH Terms
Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity.
Zhang R, Jha BK, Ogden KM, Dong B, Zhao L, Elliott R, Patton JT, Silverman RH, Weiss SR
(2013) Proc Natl Acad Sci U S A 110: 13114-9
MeSH Terms: 2',5'-Oligoadenylate Synthetase, Adenine Nucleotides, Amino Acid Sequence, Animals, Binding Sites, Capsid Proteins, Cell Line, Cells, Cultured, Endoribonucleases, Host-Pathogen Interactions, Humans, Immunity, Innate, Immunoblotting, Macrophages, Mice, Mice, Knockout, Molecular Sequence Data, Murine hepatitis virus, Mutation, Oligoribonucleotides, Phosphoric Diester Hydrolases, RNA Virus Infections, RNA Viruses, Rotavirus, Sequence Homology, Amino Acid, Viral Nonstructural Proteins
Added April 3, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Murine hepatitis virus nsp4 N258T mutants are not temperature-sensitive.
Beachboard DC, Lu X, Baker SC, Denison MR
(2013) Virology 435: 210-3
MeSH Terms: Animals, Cell Line, Mice, Murine hepatitis virus, Mutation, Temperature, Viral Nonstructural Proteins, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
8 MeSH Terms
Temperature-sensitive mutants and revertants in the coronavirus nonstructural protein 5 protease (3CLpro) define residues involved in long-distance communication and regulation of protease activity.
Stobart CC, Lee AS, Lu X, Denison MR
(2012) J Virol 86: 4801-10
MeSH Terms: Alleles, Amino Acid Sequence, Amino Acid Substitution, Animals, Coronavirus 3C Proteases, Cricetinae, Cysteine Endopeptidases, Enzyme Activation, Gene Order, Mice, Models, Molecular, Molecular Sequence Data, Murine hepatitis virus, Mutation, Phenotype, Protein Structure, Tertiary, Sequence Alignment, Temperature, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Exchange of the coronavirus replicase polyprotein cleavage sites alters protease specificity and processing.
Gadlage MJ, Denison MR
(2010) J Virol 84: 6894-8
MeSH Terms: Murine hepatitis virus, Peptide Hydrolases, Polyproteins, Protein Processing, Post-Translational, RNA-Dependent RNA Polymerase, Substrate Specificity, Viral Proteins, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
8 MeSH Terms
Murine hepatitis virus nonstructural protein 4 regulates virus-induced membrane modifications and replication complex function.
Gadlage MJ, Sparks JS, Beachboard DC, Cox RG, Doyle JD, Stobart CC, Denison MR
(2010) J Virol 84: 280-90
MeSH Terms: Coronaviridae, Glycosylation, Intracellular Membranes, Microscopy, Electron, Murine hepatitis virus, Mutant Proteins, Mutation, Missense, RNA, Viral, Viral Nonstructural Proteins, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
10 MeSH Terms
Murine coronaviruses encoding nsp2 at different genomic loci have altered replication, protein expression, and localization.
Gadlage MJ, Graham RL, Denison MR
(2008) J Virol 82: 11964-9
MeSH Terms: Animals, Mice, Murine hepatitis virus, Mutation, Open Reading Frames, Viral Nonstructural Proteins, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
7 MeSH Terms
A novel mutation in murine hepatitis virus nsp5, the viral 3C-like proteinase, causes temperature-sensitive defects in viral growth and protein processing.
Sparks JS, Donaldson EF, Lu X, Baric RS, Denison MR
(2008) J Virol 82: 5999-6008
MeSH Terms: Alanine, Amino Acid Motifs, Amino Acid Sequence, Amino Acid Substitution, Animals, Binding Sites, Conserved Sequence, Mice, Models, Molecular, Molecular Sequence Data, Murine hepatitis virus, Mutation, Protein Binding, Protein Processing, Post-Translational, Protein Structure, Tertiary, RNA, Viral, Sequence Homology, Amino Acid, Temperature, Viral Proteins
Added February 19, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms