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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 48

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Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity.
McDonald KR, Guise AJ, Pourbozorgi-Langroudi P, Cristea IM, Zakian VA, Capra JA, Sabouri N
(2016) PLoS Genet 12: e1006238
MeSH Terms: Binding Sites, DNA Helicases, DNA Replication, DNA-Directed DNA Polymerase, Genomic Instability, Multienzyme Complexes, Protein Binding, S Phase, Schizosaccharomyces, Schizosaccharomyces pombe Proteins
Added April 18, 2017
0 Communities
1 Members
0 Resources
10 MeSH Terms
Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)ยทextracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1.
Mazalouskas MD, Godoy-Ruiz R, Weber DJ, Zimmer DB, Honkanen RE, Wadzinski BE
(2014) J Biol Chem 289: 4219-32
MeSH Terms: Amino Acid Substitution, Animals, Cattle, Cell Line, Extracellular Signal-Regulated MAP Kinases, Glycoproteins, Humans, Multienzyme Complexes, Mutation, Missense, Phosphorylation, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-raf, Proto-Oncogene Proteins p21(ras), Rats, rac1 GTP-Binding Protein, ras Proteins
Added March 26, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition.
Hutchinson KE, Lipson D, Stephens PJ, Otto G, Lehmann BD, Lyle PL, Vnencak-Jones CL, Ross JS, Pietenpol JA, Sosman JA, Puzanov I, Miller VA, Pao W
(2013) Clin Cancer Res 19: 6696-702
MeSH Terms: Adult, Cell Line, Tumor, Female, High-Throughput Nucleotide Sequencing, Humans, MAP Kinase Signaling System, Male, Melanoma, Mitogen-Activated Protein Kinase Kinases, Multienzyme Complexes, Mutation, Oncogene Proteins, Fusion, Protein Kinase Inhibitors, Proto-Oncogene Proteins B-raf, Skin Neoplasms, Sulfate Adenylyltransferase
Added March 10, 2014
1 Communities
4 Members
0 Resources
16 MeSH Terms
The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development.
Venkateswaran A, Sekhar KR, Levic DS, Melville DB, Clark TA, Rybski WM, Walsh AJ, Skala MC, Crooks PA, Knapik EW, Freeman ML
(2014) Cancer Res 74: 38-43
MeSH Terms: Animals, Animals, Genetically Modified, Endothelium, Vascular, Multienzyme Complexes, NADH, NADPH Oxidoreductases, Neovascularization, Physiologic, Zebrafish
Added March 7, 2014
1 Communities
3 Members
0 Resources
7 MeSH Terms
Autotaxin as a novel serum marker of liver fibrosis.
Nakagawa H, Ikeda H, Nakamura K, Ohkawa R, Masuzaki R, Tateishi R, Yoshida H, Watanabe N, Tejima K, Kume Y, Iwai T, Suzuki A, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Omata M, Igarashi K, Aoki J, Koike K, Yatomi Y
(2011) Clin Chim Acta 412: 1201-6
MeSH Terms: Aged, Area Under Curve, Biomarkers, Female, Hepatitis C, Chronic, Humans, Liver, Liver Cirrhosis, Male, Middle Aged, Multienzyme Complexes, Phosphodiesterase I, Phosphoric Diester Hydrolases, Pyrophosphatases, ROC Curve, Retrospective Studies
Added May 2, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Targeting melanoma growth and viability reveals dualistic functionality of the phosphonothionate analogue of carba cyclic phosphatidic acid.
Altman MK, Gopal V, Jia W, Yu S, Hall H, Mills GB, McGinnis AC, Bartlett MG, Jiang G, Madan D, Prestwich GD, Xu Y, Davies MA, Murph MM
(2010) Mol Cancer 9: 140
MeSH Terms: Animals, Antineoplastic Agents, Cell Line, Tumor, Cell Survival, Gene Expression, Humans, Melanoma, Experimental, Mice, Multienzyme Complexes, Phosphatidic Acids, Phosphodiesterase I, Phosphoric Diester Hydrolases, Pyrophosphatases, RNA, Small Interfering, Receptors, Lysophosphatidic Acid, Reverse Transcriptase Polymerase Chain Reaction, Transfection, Xenograft Model Antitumor Assays
Added September 20, 2016
0 Communities
1 Members
0 Resources
18 MeSH Terms
Structures of the multicomponent Rieske non-heme iron toluene 2,3-dioxygenase enzyme system.
Friemann R, Lee K, Brown EN, Gibson DT, Eklund H, Ramaswamy S
(2009) Acta Crystallogr D Biol Crystallogr 65: 24-33
MeSH Terms: Catalytic Domain, Crystallization, Crystallography, X-Ray, Electron Transport Complex III, Flavin-Adenine Dinucleotide, Iron, Mixed Function Oxygenases, Models, Chemical, Multienzyme Complexes, NAD, Protein Binding, Pseudomonas putida, Substrate Specificity, Toluene
Added August 31, 2017
0 Communities
1 Members
0 Resources
14 MeSH Terms
How does arrestin assemble MAPKs into a signaling complex?
Song X, Coffa S, Fu H, Gurevich VV
(2009) J Biol Chem 284: 685-695
MeSH Terms: Animals, Arrestins, COS Cells, Cattle, Chlorocebus aethiops, Humans, MAP Kinase Signaling System, Mitogen-Activated Protein Kinase Kinases, Multienzyme Complexes, Protein Binding, Protein Structure, Tertiary
Added December 10, 2013
0 Communities
1 Members
0 Resources
11 MeSH Terms
Thyroid hormone effects on LKB1, MO25, phospho-AMPK, phospho-CREB, and PGC-1alpha in rat muscle.
Branvold DJ, Allred DR, Beckstead DJ, Kim HJ, Fillmore N, Condon BM, Brown JD, Sudweeks SN, Thomson DM, Winder WW
(2008) J Appl Physiol (1985) 105: 1218-27
MeSH Terms: AMP-Activated Protein Kinase Kinases, AMP-Activated Protein Kinases, Adaptor Proteins, Signal Transducing, Adaptor Proteins, Vesicular Transport, Animals, Antithyroid Agents, Blotting, Western, Calcium-Binding Proteins, Cyclic AMP Response Element-Binding Protein, Disease Models, Animal, Electric Stimulation, Hyperthyroidism, Hypothyroidism, Male, Mitochondrial Proteins, Multienzyme Complexes, Muscle, Skeletal, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Phosphoprotein Phosphatases, Phosphorylation, Promoter Regions, Genetic, Propylthiouracil, Protein Phosphatase 2C, Protein Serine-Threonine Kinases, RNA, Messenger, RNA-Binding Proteins, Rats, Rats, Sprague-Dawley, Signal Transduction, Thyroxine, Transcription Factors, Triiodothyronine
Added October 23, 2017
0 Communities
1 Members
0 Resources
32 MeSH Terms
AMP-activated protein kinase phosphorylates transcription factors of the CREB family.
Thomson DM, Herway ST, Fillmore N, Kim H, Brown JD, Barrow JR, Winder WW
(2008) J Appl Physiol (1985) 104: 429-38
MeSH Terms: AMP-Activated Protein Kinases, Acetyl-CoA Carboxylase, Activating Transcription Factor 1, Aminoimidazole Carboxamide, Animals, Cell Line, Cyclic AMP Response Element Modulator, Cyclic AMP Response Element-Binding Protein, Cyclic AMP-Dependent Protein Kinases, Enzyme Activation, Enzyme Induction, Genes, Reporter, Hexokinase, Humans, Liver, Luciferases, Male, Mice, Mice, Knockout, Multienzyme Complexes, Muscle, Skeletal, Phosphorylation, Promoter Regions, Genetic, Protein Kinase Inhibitors, Protein Serine-Threonine Kinases, Pyrazoles, Pyrimidines, Rats, Rats, Wistar, Recombinant Proteins, Ribonucleotides, Signal Transduction, Time Factors, Transfection
Added October 23, 2017
0 Communities
1 Members
0 Resources
34 MeSH Terms