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Temporal manipulation of KCC3 expression in juvenile or adult mice suggests irreversible developmental deficit in hereditary motor sensory neuropathy with agenesis of the corpus callosum.
Flores B, Delpire E
(2021) Am J Physiol Cell Physiol 320: C722-C730
MeSH Terms: Age Factors, Agenesis of Corpus Callosum, Animals, Behavior, Animal, Disease Models, Animal, Female, Ganglia, Spinal, Gene Expression Regulation, Developmental, Genetic Predisposition to Disease, Genetic Therapy, Male, Mice, Inbred C57BL, Mice, Knockout, Motor Activity, Parvalbumins, Peripheral Nervous System Diseases, Phenotype, Postural Balance, Rotarod Performance Test, Symporters
Added February 26, 2021
1 Communities
0 Members
0 Resources
20 MeSH Terms
Sex-Dependent Modulation of Anxiety and Fear by 5-HT Receptors in the Bed Nucleus of the Stria Terminalis.
Marcinkiewcz CA, Bierlein-De La Rosa G, Dorrier CE, McKnight M, DiBerto JF, Pati D, Gianessi CA, Hon OJ, Tipton G, McElligott ZA, Delpire E, Kash TL
(2019) ACS Chem Neurosci 10: 3154-3166
MeSH Terms: Animals, Anxiety, Behavior, Animal, Fear, Feeding Behavior, Female, Gene Knockdown Techniques, Male, Mice, Mice, Transgenic, Motor Activity, Neurons, Receptor, Serotonin, 5-HT1A, Septal Nuclei, Sex Factors
Added June 28, 2019
1 Communities
1 Members
0 Resources
15 MeSH Terms
Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16.
Shi CH, Rubel C, Soss SE, Sanchez-Hodge R, Zhang S, Madrigal SC, Ravi S, McDonough H, Page RC, Chazin WJ, Patterson C, Mao CY, Willis MS, Luo HY, Li YS, Stevens DA, Tang MB, Du P, Wang YH, Hu ZW, Xu YM, Schisler JC
(2018) PLoS Genet 14: e1007664
MeSH Terms: Animals, Behavior, Animal, CRISPR-Cas Systems, Cognition, Disease Models, Animal, Female, Humans, Male, Mice, Mice, Inbred C57BL, Models, Molecular, Motor Activity, Mutagenesis, Site-Directed, Phenotype, Point Mutation, Protein Domains, Protein Multimerization, Rats, Rats, Sprague-Dawley, Spinocerebellar Ataxias, Ubiquitin-Protein Ligases
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Mutual activation of glutamatergic mGlu and muscarinic M receptors reverses schizophrenia-related changes in rodents.
Cieślik P, Woźniak M, Rook JM, Tantawy MN, Conn PJ, Acher F, Tokarski K, Kusek M, Pilc A, Wierońska JM
(2018) Psychopharmacology (Berl) 235: 2897-2913
MeSH Terms: Amphetamine, Animals, Antipsychotic Agents, Disease Models, Animal, Dizocilpine Maleate, Dose-Response Relationship, Drug, Excitatory Amino Acid Agonists, Male, Mice, Motor Activity, Phosphinic Acids, Receptor, Muscarinic M4, Receptors, Metabotropic Glutamate, Rodentia, Schizophrenia
Added April 11, 2019
0 Communities
2 Members
0 Resources
MeSH Terms
Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward.
Reddy IA, Smith NK, Erreger K, Ghose D, Saunders C, Foster DJ, Turner B, Poe A, Albaugh VL, McGuinness O, Hackett TA, Grueter BA, Abumrad NN, Flynn CR, Galli A
(2018) PLoS Biol 16: e2006682
MeSH Terms: Animals, Bariatric Surgery, Behavior, Animal, Bile, Choice Behavior, Cocaine, Dopamine, Gallbladder, Ileum, Male, Mice, Inbred C57BL, Mice, Knockout, Motor Activity, Nucleus Accumbens, Reward, Signal Transduction
Added January 4, 2019
0 Communities
3 Members
0 Resources
16 MeSH Terms
mGlu and mGlu modulate distinct excitatory inputs to the nucleus accumbens shell.
Turner BD, Rook JM, Lindsley CW, Conn PJ, Grueter BA
(2018) Neuropsychopharmacology 43: 2075-2082
MeSH Terms: Animals, Cocaine, Female, Mediodorsal Thalamic Nucleus, Mice, Mice, Inbred C57BL, Mice, Transgenic, Motor Activity, Neuronal Plasticity, Neurons, Nucleus Accumbens, Optogenetics, Oxazoles, Prefrontal Cortex, Pyridines, Receptor, Metabotropic Glutamate 5, Receptors, Metabotropic Glutamate, Synapses, Synaptic Transmission
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Reduced pupil dilation during action preparation in schizophrenia.
Thakkar KN, Brascamp JW, Ghermezi L, Fifer K, Schall JD, Park S
(2018) Int J Psychophysiol 128: 111-118
MeSH Terms: Adult, Executive Function, Female, Humans, Inhibition, Psychological, Male, Middle Aged, Motor Activity, Pupil, Saccades, Schizophrenia
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Reduced Nonexercise Activity Attenuates Negative Energy Balance in Mice Engaged in Voluntary Exercise.
Lark DS, Kwan JR, McClatchey PM, James MN, James FD, Lighton JRB, Lantier L, Wasserman DH
(2018) Diabetes 67: 831-840
MeSH Terms: Animals, Behavior, Animal, Calorimetry, Indirect, Energy Intake, Energy Metabolism, Male, Mice, Mice, Inbred C57BL, Motor Activity, Obesity, Physical Conditioning, Animal, Weight Loss
Added March 26, 2019
1 Communities
1 Members
0 Resources
MeSH Terms
Mechanisms Associated With Physical Activity Behavior: Insights From Rodent Experiments.
Roberts MD, Ruegsegger GN, Brown JD, Booth FW
(2017) Exerc Sport Sci Rev 45: 217-222
MeSH Terms: Animals, Behavior, Animal, Dopaminergic Neurons, Motor Activity, Nucleus Accumbens, Rats, Signal Transduction
Added October 23, 2017
0 Communities
1 Members
0 Resources
7 MeSH Terms
OCD candidate gene /EAAT3 impacts basal ganglia-mediated activity and stereotypic behavior.
Zike ID, Chohan MO, Kopelman JM, Krasnow EN, Flicker D, Nautiyal KM, Bubser M, Kellendonk C, Jones CK, Stanwood G, Tanaka KF, Moore H, Ahmari SE, Veenstra-VanderWeele J
(2017) Proc Natl Acad Sci U S A 114: 5719-5724
MeSH Terms: Amphetamines, Animals, Basal Ganglia, Cell Line, Central Nervous System Stimulants, Dopamine, Excitatory Amino Acid Transporter 3, Glutamic Acid, Grooming, Maze Learning, Mice, Mice, Inbred C57BL, Mice, Transgenic, Motor Activity, Obsessive-Compulsive Disorder, Receptors, Dopamine D1, Reflex, Startle
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms