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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 1071

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Collagen IV dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial Goodpasture's and Alport diseases.
Pokidysheva EN, Seeger H, Pedchenko V, Chetyrkin S, Bergmann C, Abrahamson D, Cui ZW, Delpire E, Fervenza FC, Fidler AL, Fogo AB, Gaspert A, Grohmann M, Gross O, Haddad G, Harris RC, Kashtan C, Kitching AR, Lorenzen JM, McAdoo S, Pusey CD, Segelmark M, Simmons A, Voziyan PA, Wagner T, Wüthrich RP, Zhao MH, Boudko SP, Kistler AD, Hudson BG
(2021) J Biol Chem 296: 100590
MeSH Terms: Animals, Anti-Glomerular Basement Membrane Disease, Collagen Type IV, Mice, Models, Molecular, Mutation, Nephritis, Hereditary, Protein Multimerization, Protein Structure, Quaternary, Signal Transduction
Added September 3, 2021
1 Communities
0 Members
0 Resources
MeSH Terms
Predicting susceptibility to SARS-CoV-2 infection based on structural differences in ACE2 across species.
Alexander MR, Schoeder CT, Brown JA, Smart CD, Moth C, Wikswo JP, Capra JA, Meiler J, Chen W, Madhur MS
(2020) FASEB J 34: 15946-15960
MeSH Terms: Amino Acid Sequence, Angiotensin-Converting Enzyme 2, Animals, COVID-19, Camelus, Genetic Predisposition to Disease, Glycosylation, Horses, Humans, Models, Molecular, Phylogeny, Protein Binding, Protein Structure, Tertiary, Receptors, Virus, SARS-CoV-2, Sequence Alignment, Species Specificity
Added September 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Probing biophysical sequence constraints within the transmembrane domains of rhodopsin by deep mutational scanning.
Penn WD, McKee AG, Kuntz CP, Woods H, Nash V, Gruenhagen TC, Roushar FJ, Chandak M, Hemmerich C, Rusch DB, Meiler J, Schlebach JP
(2020) Sci Adv 6: eaay7505
MeSH Terms: Cell Membrane, Gene Expression, HEK293 Cells, Humans, Hydrophobic and Hydrophilic Interactions, Lipid Bilayers, Models, Molecular, Mutation, Protein Domains, Protein Folding, Protein Structure, Secondary, Recombinant Proteins, Rhodopsin, Solubility, Thermodynamics
Added March 21, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Specificity and affinity of the N-terminal residues in staphylocoagulase in binding to prothrombin.
Maddur AA, Kroh HK, Aschenbrenner ME, Gibson BHY, Panizzi P, Sheehan JH, Meiler J, Bock PE, Verhamme IM
(2020) J Biol Chem 295: 5614-5625
MeSH Terms: Bacterial Proteins, Binding Sites, Coagulase, Humans, Models, Molecular, Protein Binding, Prothrombin, Staphylococcal Infections, Staphylococcus aureus, Substrate Specificity
Added March 21, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
Structural analysis of lecithin:cholesterol acyltransferase bound to high density lipoprotein particles.
Manthei KA, Patra D, Wilson CJ, Fawaz MV, Piersimoni L, Shenkar JC, Yuan W, Andrews PC, Engen JR, Schwendeman A, Ohi MD, Tesmer JJG
(2020) Commun Biol 3: 28
MeSH Terms: Binding Sites, Catalytic Domain, Lipoproteins, HDL, Lysine, Mass Spectrometry, Models, Molecular, Multiprotein Complexes, Phosphatidylcholine-Sterol O-Acyltransferase, Protein Binding, Protein Conformation, Recombinant Proteins, Structure-Activity Relationship
Added March 3, 2020
0 Communities
1 Members
0 Resources
12 MeSH Terms
Delineating the Molecular Basis of the Calmodulin‒bMunc13-2 Interaction by Cross-Linking/Mass Spectrometry-Evidence for a Novel CaM Binding Motif in bMunc13-2.
Piotrowski C, Moretti R, Ihling CH, Haedicke A, Liepold T, Lipstein N, Meiler J, Jahn O, Sinz A
(2020) Cells 9:
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Binding Sites, Calmodulin, Cattle, Cross-Linking Reagents, Hydrophobic and Hydrophilic Interactions, Mass Spectrometry, Models, Molecular, Nerve Tissue Proteins, Protein Binding, Protein Domains, Rats, Swine
Added March 21, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
A key interaction with RPA orients XPA in NER complexes.
Topolska-Woś AM, Sugitani N, Cordoba JJ, Le Meur KV, Le Meur RA, Kim HS, Yeo JE, Rosenberg D, Hammel M, Schärer OD, Chazin WJ
(2020) Nucleic Acids Res 48: 2173-2188
MeSH Terms: DNA, DNA Damage, DNA Repair, DNA, Single-Stranded, DNA-Binding Proteins, Humans, Magnetic Resonance Spectroscopy, Models, Molecular, Protein Binding, Replication Protein A, Xeroderma Pigmentosum Group A Protein
Added March 11, 2020
0 Communities
1 Members
0 Resources
11 MeSH Terms
Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist.
Azumaya CM, Linton EA, Risener CJ, Nakagawa T, Karakas E
(2020) J Biol Chem 295: 1743-1753
MeSH Terms: Binding Sites, Calcium Signaling, Cryoelectron Microscopy, Humans, Inositol 1,4,5-Trisphosphate, Inositol 1,4,5-Trisphosphate Receptors, Models, Molecular, Peptides, Protein Conformation
Added March 3, 2020
0 Communities
2 Members
0 Resources
9 MeSH Terms
Microtubules Regulate Localization and Availability of Insulin Granules in Pancreatic Beta Cells.
Bracey KM, Ho KH, Yampolsky D, Gu G, Kaverina I, Holmes WR
(2020) Biophys J 118: 193-206
MeSH Terms: Animals, Insulin, Insulin-Secreting Cells, Mice, Microtubules, Models, Molecular
Added December 4, 2020
1 Communities
1 Members
0 Resources
6 MeSH Terms
Federating Structural Models and Data: Outcomes from A Workshop on Archiving Integrative Structures.
Berman HM, Adams PD, Bonvin AA, Burley SK, Carragher B, Chiu W, DiMaio F, Ferrin TE, Gabanyi MJ, Goddard TD, Griffin PR, Haas J, Hanke CA, Hoch JC, Hummer G, Kurisu G, Lawson CL, Leitner A, Markley JL, Meiler J, Montelione GT, Phillips GN, Prisner T, Rappsilber J, Schriemer DC, Schwede T, Seidel CAM, Strutzenberg TS, Svergun DI, Tajkhorshid E, Trewhella J, Vallat B, Velankar S, Vuister GW, Webb B, Westbrook JD, White KL, Sali A
(2019) Structure 27: 1745-1759
MeSH Terms: Computational Biology, Crystallography, X-Ray, Databases, Protein, Magnetic Resonance Spectroscopy, Models, Molecular, Protein Conformation, Proteins
Added March 21, 2020
0 Communities
1 Members
0 Resources
7 MeSH Terms