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Microvascular disease confers additional risk to COVID-19 infection.
Bale BF, Doneen AL, Vigerust DJ
(2020) Med Hypotheses 144: 109999
MeSH Terms: Adult, Aging, COVID-19, Cardiovascular Diseases, Child, Diabetes Mellitus, Disease Susceptibility, Humans, Hydrogen Peroxide, Hypertension, Hypochlorous Acid, Immunity, Innate, Lung, Microcirculation, Microvessels, Neutrophils, Pandemics, Peroxidase, Risk Factors, United States
Added June 25, 2020
0 Communities
1 Members
0 Resources
20 MeSH Terms
Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease.
Bersini S, Arrojo E Drigo R, Huang L, Shokhirev MN, Hetzer MW
(2020) Adv Biosyst 4: e2000044
MeSH Terms: Aged, Aging, Alzheimer Disease, Endothelial Cells, Female, Fibroblasts, Humans, Male, Microfluidic Analytical Techniques, Microvessels
Added April 14, 2021
0 Communities
1 Members
0 Resources
10 MeSH Terms
Rapid changes in the microvascular circulation of skeletal muscle impair insulin delivery during sepsis.
Mignemi NA, McClatchey PM, Kilchrist KV, Williams IM, Millis BA, Syring KE, Duvall CL, Wasserman DH, McGuinness OP
(2019) Am J Physiol Endocrinol Metab 316: E1012-E1023
MeSH Terms: Animals, Capillaries, Capillary Permeability, Disease Models, Animal, Echocardiography, Hyperglycemia, Insulin, Insulin Resistance, Lipopolysaccharides, Mice, Microcirculation, Microvessels, Muscle Fibers, Skeletal, Muscle, Skeletal, Sepsis
Added March 26, 2019
1 Communities
1 Members
0 Resources
15 MeSH Terms
iPSC-Derived Brain Endothelium Exhibits Stable, Long-Term Barrier Function in Perfused Hydrogel Scaffolds.
Faley SL, Neal EH, Wang JX, Bosworth AM, Weber CM, Balotin KM, Lippmann ES, Bellan LM
(2019) Stem Cell Reports 12: 474-487
MeSH Terms: Albumins, Blood-Brain Barrier, Brain, Cells, Cultured, Dextrans, Endothelial Cells, Endothelium, Fluorescein, Humans, Hydrogels, Induced Pluripotent Stem Cells, Microvessels
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Ultrasound Measurement of Vascular Density to Evaluate Response to Anti-Angiogenic Therapy in Renal Cell Carcinoma.
Rojas JD, Papadopoulou V, Czernuszewicz TJ, Rajamahendiran RM, Chytil A, Chiang YC, Chong DC, Bautch VL, Rathmell WK, Aylward S, Gessner RC, Dayton PA
(2019) IEEE Trans Biomed Eng 66: 873-880
MeSH Terms: Angiogenesis Inhibitors, Angiography, Animals, Carcinoma, Renal Cell, Drug Monitoring, Female, Heterografts, Kidney, Kidney Neoplasms, Mice, Mice, Inbred NOD, Mice, SCID, Microvessels, Ultrasonography
Added October 30, 2019
0 Communities
1 Members
0 Resources
14 MeSH Terms
Automated quantification of microvascular perfusion.
McClatchey PM, Mignemi NA, Xu Z, Williams IM, Reusch JEB, McGuinness OP, Wasserman DH
(2018) Microcirculation 25: e12482
MeSH Terms: Animals, Automation, Blood Flow Velocity, Hematocrit, Mice, Microcirculation, Microscopy, Fluorescence, Microscopy, Video, Microvessels, Perfusion, Phenylephrine, Reproducibility of Results, Saline Solution, Software
Added March 26, 2019
1 Communities
1 Members
0 Resources
14 MeSH Terms
Von Hippel-Lindau mutations disrupt vascular patterning and maturation via Notch.
Arreola A, Payne LB, Julian MH, de Cubas AA, Daniels AB, Taylor S, Zhao H, Darden J, Bautch VL, Rathmell WK, Chappell JC
(2018) JCI Insight 3:
MeSH Terms: Animals, Diamines, Disease Models, Animal, Endothelial Cells, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Hemangioblastoma, Humans, Male, Mice, Mice, Transgenic, Microvessels, Mutation, Receptors, Notch, Retinal Artery, Thiazoles, Von Hippel-Lindau Tumor Suppressor Protein, von Hippel-Lindau Disease
Added October 30, 2019
0 Communities
2 Members
0 Resources
19 MeSH Terms
Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury.
Shaver CM, Wickersham N, McNeil JB, Nagata H, Miller A, Landstreet SR, Kuck JL, Diamond JM, Lederer DJ, Kawut SM, Palmer SM, Wille KM, Weinacker A, Lama VN, Crespo MM, Orens JB, Shah PD, Hage CA, Cantu E, Porteous MK, Dhillon G, McDyer J, Bastarache JA, Christie JD, Ware LB, Lung Transplant Outcomes Group (LTOG)
(2018) JCI Insight 3:
MeSH Terms: Acetaminophen, Allografts, Capillary Permeability, Case-Control Studies, Cell Line, Endothelial Cells, Female, Hemoglobins, Humans, Hyperoxia, Lung, Lung Transplantation, Male, Microvessels, Middle Aged, Oxidative Stress, Primary Graft Dysfunction
Added May 31, 2018
0 Communities
1 Members
0 Resources
17 MeSH Terms
Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction.
Gaskill CF, Carrier EJ, Kropski JA, Bloodworth NC, Menon S, Foronjy RF, Taketo MM, Hong CC, Austin ED, West JD, Means AL, Loyd JE, Merryman WD, Hemnes AR, De Langhe S, Blackwell TS, Klemm DJ, Majka SM
(2017) J Clin Invest 127: 2262-2276
MeSH Terms: ATP Binding Cassette Transporter, Subfamily G, Member 2, Animals, Bone Morphogenetic Protein Receptors, Type II, Cell Differentiation, Cell Lineage, Cells, Cultured, Humans, Lung, Mesenchymal Stem Cells, Mice, Transgenic, Microvessels, Neovascularization, Pathologic, Pericytes, Protein Stability, Pulmonary Fibrosis, Vasoconstriction, Wnt Signaling Pathway
Added June 6, 2017
0 Communities
3 Members
0 Resources
17 MeSH Terms
Matrix stiffening promotes a tumor vasculature phenotype.
Bordeleau F, Mason BN, Lollis EM, Mazzola M, Zanotelli MR, Somasegar S, Califano JP, Montague C, LaValley DJ, Huynh J, Mencia-Trinchant N, Negrón Abril YL, Hassane DC, Bonassar LJ, Butcher JT, Weiss RS, Reinhart-King CA
(2017) Proc Natl Acad Sci U S A 114: 492-497
MeSH Terms: Animals, Biomechanical Phenomena, Cattle, Cells, Cultured, Chick Embryo, Collagen, Extracellular Matrix, Female, Human Umbilical Vein Endothelial Cells, Humans, Mammary Neoplasms, Experimental, Matrix Metalloproteinases, Mice, Microvessels, Neoplasm Invasiveness, Neovascularization, Pathologic, Phenotype, Tumor Microenvironment, Vascular Stiffness
Added April 10, 2019
0 Communities
1 Members
0 Resources
MeSH Terms