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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 214

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Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, Sagalovskiy IR, Ma A, Kapilian J, Firl CEM, Decker AR, Sastra SA, Palermo CF, Andrade LR, Sajjakulnukit P, Zhang L, Tolstyka ZP, Hirschhorn T, Lamb C, Liu T, Gu W, Seeley ES, Stone E, Georgiou G, Manor U, Iuga A, Wahl GM, Stockwell BR, Lyssiotis CA, Olive KP
(2020) Science 368: 85-89
MeSH Terms: Animals, Carcinoma, Pancreatic Ductal, Cationic Amino Acid Transporter 1, Cell Line, Tumor, Cystathionine gamma-Lyase, Cysteine, Cystine, Ferroptosis, Gene Deletion, Humans, Mice, Mice, Mutant Strains, Pancreatic Neoplasms
Added March 13, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
A mutation in the Na-K-2Cl cotransporter-1 leads to changes in cellular metabolism.
Omer S, Koumangoye R, Delpire E
(2020) J Cell Physiol 235: 7239-7250
MeSH Terms: Adolescent, Animals, Cell Line, DNA, Mitochondrial, Dogs, Energy Metabolism, Female, Fibroblasts, Glycolysis, Humans, Madin Darby Canine Kidney Cells, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Microscopy, Electron, Transmission, Mitochondria, Multiple Organ Failure, Mutant Proteins, Mutation, Recombinant Fusion Proteins, Sequence Deletion, Solute Carrier Family 12, Member 2
Added February 28, 2020
1 Communities
1 Members
0 Resources
22 MeSH Terms
Inhibition of Epidermal Growth Factor Receptor Activation Is Associated With Improved Diabetic Nephropathy and Insulin Resistance in Type 2 Diabetes.
Li Z, Li Y, Overstreet JM, Chung S, Niu A, Fan X, Wang S, Wang Y, Zhang MZ, Harris RC
(2018) Diabetes 67: 1847-1857
MeSH Terms: Albuminuria, Animals, Biomarkers, Crosses, Genetic, Cytokines, Diabetes Mellitus, Type 2, Diabetic Nephropathies, ErbB Receptors, Erlotinib Hydrochloride, Fibrosis, Glomerulonephritis, Hypoglycemic Agents, Insulin Resistance, Kidney, Macrophages, Membrane Transport Modulators, Mice, Knockout, Mice, Mutant Strains, Nitric Oxide Synthase Type III, Oxidative Stress, Protein Kinase Inhibitors, T-Lymphocytes, Transforming Growth Factor alpha
Added November 9, 2018
1 Communities
0 Members
0 Resources
23 MeSH Terms
Bacterial-derived Neutrophilic Inflammation Drives Lung Remodeling in a Mouse Model of Chronic Obstructive Pulmonary Disease.
Richmond BW, Du RH, Han W, Benjamin JT, van der Meer R, Gleaves L, Guo M, McKissack A, Zhang Y, Cheng DS, Polosukhin VV, Blackwell TS
(2018) Am J Respir Cell Mol Biol 58: 736-744
MeSH Terms: Airway Remodeling, Aminopyridines, Animals, Bacillus, Benzamides, Cyclopropanes, Disease Models, Animal, Mice, Inbred C57BL, Mice, Mutant Strains, Neutrophils, Pneumonia, Bacterial, Pulmonary Disease, Chronic Obstructive, Pulmonary Emphysema, Receptors, Cell Surface
Added March 21, 2018
0 Communities
3 Members
0 Resources
14 MeSH Terms
The synthetic neuroactive steroid SGE-516 reduces seizure burden and improves survival in a Dravet syndrome mouse model.
Hawkins NA, Lewis M, Hammond RS, Doherty JJ, Kearney JA
(2017) Sci Rep 7: 15327
MeSH Terms: Animals, Anticonvulsants, Epilepsies, Myoclonic, GABA-A Receptor Agonists, Hydroxycholesterols, Mice, Mice, Mutant Strains, NAV1.1 Voltage-Gated Sodium Channel, Receptors, GABA-A
Added October 2, 2018
1 Communities
0 Members
0 Resources
9 MeSH Terms
A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry.
Zhang J, Weinrich JAP, Russ JB, Comer JD, Bommareddy PK, DiCasoli RJ, Wright CVE, Li Y, van Roessel PJ, Kaltschmidt JA
(2017) Cell Rep 21: 666-678
MeSH Terms: Animals, Biomarkers, Dystonia, GABAergic Neurons, Genetic Predisposition to Disease, Interneurons, Male, Mice, Mutant Strains, Molecular Chaperones, Mutation, Nerve Net, Presynaptic Terminals, Proprioception, Spinal Cord, Transcription Factors
Added November 7, 2017
1 Communities
1 Members
0 Resources
15 MeSH Terms
Peripheral motor neuropathy is associated with defective kinase regulation of the KCC3 cotransporter.
Kahle KT, Flores B, Bharucha-Goebel D, Zhang J, Donkervoort S, Hegde M, Hussain G, Duran D, Liang B, Sun D, Bönnemann CG, Delpire E
(2016) Sci Signal 9: ra77
MeSH Terms: Animals, Female, HEK293 Cells, Humans, Male, Mice, Mice, Mutant Strains, Motor Neurons, Mutation, Missense, Peripheral Nervous System Diseases, Phosphorylation, Symporters, WNK Lysine-Deficient Protein Kinase 1
Added August 22, 2016
1 Communities
0 Members
0 Resources
13 MeSH Terms
The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis.
Thiele Orberg E, Fan H, Tam AJ, Dejea CM, Destefano Shields CE, Wu S, Chung L, Finard BB, Wu X, Fathi P, Ganguly S, Fu J, Pardoll DM, Sears CL, Housseau F
(2017) Mucosal Immunol 10: 421-433
MeSH Terms: Animals, Arginase, Bacterial Toxins, Bacteroides Infections, Bacteroides fragilis, Carcinogenesis, Cell Differentiation, Cell Proliferation, Cells, Cultured, Colon, Colorectal Neoplasms, Disease Models, Animal, Epithelial Cells, Genes, APC, Humans, Immune Tolerance, Interleukin-17, Metalloendopeptidases, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Myeloid-Derived Suppressor Cells, Nitric Oxide Synthase Type II, T-Lymphocytes, Transcriptome
Added March 20, 2018
0 Communities
1 Members
0 Resources
25 MeSH Terms
Serotonin transporter variant drives preventable gastrointestinal abnormalities in development and function.
Margolis KG, Li Z, Stevanovic K, Saurman V, Israelyan N, Anderson GM, Snyder I, Veenstra-VanderWeele J, Blakely RD, Gershon MD
(2016) J Clin Invest 126: 2221-35
MeSH Terms: Animals, Autism Spectrum Disorder, Enteric Nervous System, Female, Gastrointestinal Motility, Gastrointestinal Tract, Genetic Variation, Humans, Male, Mice, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, Mice, Mutant Strains, Models, Animal, Neurogenesis, Pregnancy, Serotonin, Serotonin Plasma Membrane Transport Proteins
Added August 31, 2018
1 Communities
0 Members
0 Resources
MeSH Terms
3-D imaging mass spectrometry of protein distributions in mouse Neurofibromatosis 1 (NF1)-associated optic glioma.
Anderson DM, Van de Plas R, Rose KL, Hill S, Schey KL, Solga AC, Gutmann DH, Caprioli RM
(2016) J Proteomics 149: 77-84
MeSH Terms: Animals, Brain Neoplasms, Diazepam Binding Inhibitor, Fiducial Markers, Imaging, Three-Dimensional, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Molecular Imaging, Myelin Basic Protein, Neurofibromatosis 1, Optic Chiasm, Optic Nerve Glioma, Optic Nerve Neoplasms, Proteomics, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Added February 22, 2016
1 Communities
2 Members
0 Resources
16 MeSH Terms