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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 62

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Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group.
Irvin MR, Sitlani CM, Floyd JS, Psaty BM, Bis JC, Wiggins KL, Whitsel EA, Sturmer T, Stewart J, Raffield L, Sun F, Liu CT, Xu H, Cupples AL, Tanner RM, Rossing P, Smith A, Zilhão NR, Launer LJ, Noordam R, Rotter JI, Yao J, Li X, Guo X, Limdi N, Sundaresan A, Lange L, Correa A, Stott DJ, Ford I, Jukema JW, Gudnason V, Mook-Kanamori DO, Trompet S, Palmas W, Warren HR, Hellwege JN, Giri A, O'donnell C, Hung AM, Edwards TL, Ahluwalia TS, Arnett DK, Avery CL
(2019) Am J Hypertens 32: 1146-1153
MeSH Terms: African Americans, Aged, Antihypertensive Agents, Blood Pressure, Case-Control Studies, DNA (Cytosine-5-)-Methyltransferases, DNA Methyltransferase 3A, DNA-Binding Proteins, Drug Resistance, Dystrophin-Associated Proteins, Europe, Female, Genetic Loci, Genome-Wide Association Study, Humans, Hypertension, Male, Middle Aged, Myosin Heavy Chains, Myosin Type V, Neuropeptides, Pharmacogenetics, Pharmacogenomic Variants, Polymorphism, Single Nucleotide, Risk Assessment, Risk Factors, Transcription Factors, United States, Whites
Added March 3, 2020
0 Communities
1 Members
0 Resources
29 MeSH Terms
The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains.
Starbird CA, Perry NA, Chen Q, Berndt S, Yamakawa I, Loukachevitch LV, Limbrick EM, Bachmann BO, Iverson TM, McCulloch KM
(2018) Biochemistry 57: 6827-6837
MeSH Terms: Amino Acid Sequence, Aminoglycosides, Bacterial Proteins, Biosynthetic Pathways, Catalytic Domain, Conserved Sequence, Crystallography, X-Ray, Gene Fusion, Genes, Bacterial, Methyltransferases, Micromonospora, Models, Molecular, Oxygenases, Protein Interaction Domains and Motifs, Sequence Homology, Amino Acid
Added April 1, 2019
0 Communities
1 Members
0 Resources
15 MeSH Terms
HemX Modulates Glutamyl-tRNA Reductase Abundance To Regulate Heme Biosynthesis.
Choby JE, Grunenwald CM, Celis AI, Gerdes SY, DuBois JL, Skaar EP
(2018) mBio 9:
MeSH Terms: Aldehyde Oxidoreductases, Bacterial Proteins, Gene Deletion, Gene Expression, Gene Expression Regulation, Bacterial, Heme, Methyltransferases, Staphylococcus aureus
Added March 15, 2018
0 Communities
1 Members
0 Resources
8 MeSH Terms
Set2 methyltransferase facilitates cell cycle progression by maintaining transcriptional fidelity.
Dronamraju R, Jha DK, Eser U, Adams AT, Dominguez D, Choudhury R, Chiang YC, Rathmell WK, Emanuele MJ, Churchman LS, Strahl BD
(2018) Nucleic Acids Res 46: 1331-1344
MeSH Terms: Anaphase-Promoting Complex-Cyclosome, Biological Evolution, Cdc20 Proteins, Cell Cycle, Gene Expression Regulation, Fungal, Histone-Lysine N-Methyltransferase, Histones, Humans, Lysine, Methylation, Methyltransferases, Nocodazole, Protein Processing, Post-Translational, Proteolysis, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Transcription, Genetic, Tubulin Modulators
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation.
Osipovich AB, Gangula R, Vianna PG, Magnuson MA
(2016) Development 143: 4595-4607
MeSH Terms: Acetylation, Animals, Apoptosis, Carrier Proteins, Cell Cycle, Cell Differentiation, Cell Proliferation, Cells, Cultured, Chromatin, Embryonic Development, Embryonic Stem Cells, Gene Expression Regulation, Heart Defects, Congenital, Histones, Methyltransferases, Mice, Mice, Knockout, Myocytes, Cardiac, Neural Tube, Promoter Regions, Genetic, RNA, Untranslated, Transcription, Genetic
Added November 30, 2016
2 Communities
2 Members
0 Resources
22 MeSH Terms
Structure/Function Analysis of Recurrent Mutations in SETD2 Protein Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and Histone H3 Lys-36 Trimethylation.
Hacker KE, Fahey CC, Shinsky SA, Chiang YJ, DiFiore JV, Jha DK, Vo AH, Shavit JA, Davis IJ, Strahl BD, Rathmell WK
(2016) J Biol Chem 291: 21283-21295
MeSH Terms: Enzyme Stability, Histone-Lysine N-Methyltransferase, Histones, Humans, Methylation, Methyltransferases, Mutation, Neoplasm Proteins, Neoplasms, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Structure-Activity Relationship
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex.
Duvall-Noelle N, Karwandyar A, Richmond A, Raman D
(2016) Oncogene 35: 1122-33
MeSH Terms: Active Transport, Cell Nucleus, Adaptor Proteins, Signal Transducing, Benzylamines, Breast Neoplasms, CCAAT-Enhancer-Binding Proteins, Cell Line, Tumor, Chemokine CXCL12, Cyclams, Cytoskeletal Proteins, DNA (Cytosine-5-)-Methyltransferase 1, DNA (Cytosine-5-)-Methyltransferases, Epigenesis, Genetic, Gene Knockdown Techniques, Heterocyclic Compounds, Histocompatibility Antigens, Histone-Lysine N-Methyltransferase, Histones, Humans, LIM Domain Proteins, Prognosis, Proteomics, Signal Transduction, Snail Family Transcription Factors, Transcription Factors, Tumor Microenvironment, Ubiquitin-Protein Ligases
Added May 20, 2015
2 Communities
2 Members
0 Resources
26 MeSH Terms
Age- and pregnancy-associated DNA methylation changes in mammary epithelial cells.
Huh SJ, Clement K, Jee D, Merlini A, Choudhury S, Maruyama R, Yoo R, Chytil A, Boyle P, Ran FA, Moses HL, Barcellos-Hoff MH, Jackson-Grusby L, Meissner A, Polyak K
(2015) Stem Cell Reports 4: 297-311
MeSH Terms: Age Factors, Animals, Antigens, Surface, Cell Differentiation, Cluster Analysis, DNA (Cytosine-5-)-Methyltransferase 1, DNA (Cytosine-5-)-Methyltransferases, DNA Methylation, Enhancer Elements, Genetic, Enzyme Activation, Epigenesis, Genetic, Epithelial Cells, Female, Gene Expression Profiling, Gene Expression Regulation, Histones, Immunophenotyping, Mammary Glands, Animal, Mice, Mice, Knockout, Organ Specificity, Phenotype, Pregnancy, Promoter Regions, Genetic, Sexual Maturation, Signal Transduction
Added February 5, 2016
1 Communities
1 Members
0 Resources
26 MeSH Terms
DNA methyltransferase 3a and mitogen-activated protein kinase signaling regulate the expression of fibroblast growth factor-inducible 14 (Fn14) during denervation-induced skeletal muscle atrophy.
Tajrishi MM, Shin J, Hetman M, Kumar A
(2014) J Biol Chem 289: 19985-99
MeSH Terms: Animals, Base Sequence, Conserved Sequence, CpG Islands, DNA, DNA (Cytosine-5-)-Methyltransferases, DNA Methylation, DNA Methyltransferase 3A, Gene Expression, Gene Knockdown Techniques, MAP Kinase Signaling System, Mice, Mice, Inbred C57BL, Models, Biological, Molecular Sequence Data, Muscle Denervation, Muscle, Skeletal, Muscular Atrophy, Promoter Regions, Genetic, RNA, Small Interfering, Receptors, Tumor Necrosis Factor, Sequence Homology, Nucleic Acid, Sp1 Transcription Factor, TWEAK Receptor, Transcription Factor AP-1
Added October 30, 2014
0 Communities
1 Members
0 Resources
25 MeSH Terms
Challenges in interpreting the evidence for genetic predictors of ototoxicity.
Ratain MJ, Cox NJ, Henderson TO
(2013) Clin Pharmacol Ther 94: 631-5
MeSH Terms: Antineoplastic Agents, Catechol O-Methyltransferase, Cisplatin, Female, Genetic Variation, Hearing Loss, Humans, Male, Methyltransferases, Multidrug Resistance-Associated Proteins
Added February 22, 2016
0 Communities
1 Members
0 Resources
10 MeSH Terms