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Results: 1 to 4 of 4

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Oxidative stress, caspase-3 activation and cleavage of ROCK-1 play an essential role in MeHg-induced cell death in primary astroglial cells.
Dos Santos AA, López-Granero C, Farina M, Rocha JBT, Bowman AB, Aschner M
(2018) Food Chem Toxicol 113: 328-336
MeSH Terms: Animals, Astrocytes, Caspase 3, Caspase 9, Cell Death, Cells, Cultured, Enzyme Activation, Lim Kinases, Methylmercury Compounds, Mice, Inbred C57BL, Myosin-Light-Chain Phosphatase, Oxidative Stress, Phosphorylation, Proteolysis, rho-Associated Kinases
Added April 11, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
Sex- and structure-specific differences in antioxidant responses to methylmercury during early development.
Ruszkiewicz JA, Bowman AB, Farina M, Rocha JBT, Aschner M
(2016) Neurotoxicology 56: 118-126
MeSH Terms: Animals, Animals, Newborn, Antioxidants, Brain, Female, Gene Expression Regulation, Developmental, Glutathione, Glutathione Peroxidase, Male, Methylmercury Compounds, Mice, Mice, Inbred C57BL, Pregnancy, Prenatal Exposure Delayed Effects, RNA, Messenger, Sex Characteristics, Thioredoxin-Disulfide Reductase, Thioredoxins
Added April 26, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper.
Aboud AA, Tidball AM, Kumar KK, Neely MD, Han B, Ess KC, Hong CC, Erikson KM, Hedera P, Bowman AB
(2015) Neurobiol Dis 73: 204-12
MeSH Terms: Adult, Cadmium, Cell Line, Copper, Genetic Predisposition to Disease, Humans, Induced Pluripotent Stem Cells, Male, Manganese, Membrane Potential, Mitochondrial, Methylmercury Compounds, Mitochondria, Mutation, Neural Stem Cells, Parkinson Disease, Risk Factors, Ubiquitin-Protein Ligases
Added December 16, 2014
2 Communities
4 Members
0 Resources
17 MeSH Terms
Characterization of the effects of methylmercury on Caenorhabditis elegans.
Helmcke KJ, Syversen T, Miller DM, Aschner M
(2009) Toxicol Appl Pharmacol 240: 265-72
MeSH Terms: Animals, Caenorhabditis elegans, Dose-Response Relationship, Drug, Drug Resistance, Environmental Pollutants, Larva, Longevity, Methylmercury Compounds, Nervous System, Neurogenesis, Neurons, Pharyngeal Muscles, Reproduction, Time Factors
Added February 3, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms