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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 7 of 7

Publication Record

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A Coordinated Attack: Rett Syndrome Therapeutic Development.
Gogliotti RG, Niswender CM
(2019) Trends Pharmacol Sci 40: 233-236
MeSH Terms: Animals, Drug Discovery, Drug Evaluation, Preclinical, Drug Repositioning, Female, Humans, Methyl-CpG-Binding Protein 2, Mutation, Research Design, Rett Syndrome
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Contextual Fear Extinction Induces Hippocampal Metaplasticity Mediated by Metabotropic Glutamate Receptor 5.
Stansley BJ, Fisher NM, Gogliotti RG, Lindsley CW, Conn PJ, Niswender CM
(2018) Cereb Cortex 28: 4291-4304
MeSH Terms: Animals, Extinction, Psychological, Fear, Hippocampus, Long-Term Potentiation, Long-Term Synaptic Depression, Male, Methyl-CpG-Binding Protein 2, Mice, Inbred C57BL, Mice, Transgenic, Receptor, Cannabinoid, CB1, Receptors, Kainic Acid, Receptors, N-Methyl-D-Aspartate
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
mGlu potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome.
Gogliotti RG, Senter RK, Fisher NM, Adams J, Zamorano R, Walker AG, Blobaum AL, Engers DW, Hopkins CR, Daniels JS, Jones CK, Lindsley CW, Xiang Z, Conn PJ, Niswender CM
(2017) Sci Transl Med 9:
MeSH Terms: Animals, Apnea, Autopsy, CA1 Region, Hippocampal, Cognition, Disease Models, Animal, Dose-Response Relationship, Drug, Female, Humans, Long-Term Potentiation, Male, Memory, Methyl-CpG-Binding Protein 2, Mice, Motor Cortex, Neuronal Plasticity, Phenotype, Picolinic Acids, RNA, Messenger, Rats, Sprague-Dawley, Receptors, Metabotropic Glutamate, Respiration, Rett Syndrome, Social Behavior, Transcription, Genetic
Added March 3, 2020
0 Communities
2 Members
0 Resources
MeSH Terms
mGlu5 positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome.
Gogliotti RG, Senter RK, Rook JM, Ghoshal A, Zamorano R, Malosh C, Stauffer SR, Bridges TM, Bartolome JM, Daniels JS, Jones CK, Lindsley CW, Conn PJ, Niswender CM
(2016) Hum Mol Genet 25: 1990-2004
MeSH Terms: Adult, Allosteric Regulation, Animals, Autistic Disorder, Autopsy, Disease Models, Animal, Female, Gene Expression Regulation, Hippocampus, Humans, Male, Methyl-CpG-Binding Protein 2, Mice, Mice, Knockout, Motor Cortex, Neuronal Plasticity, Pyrazoles, Pyrimidinones, Receptor, Metabotropic Glutamate 5, Rett Syndrome, Seizures, Signal Transduction, Young Adult
Added April 6, 2017
0 Communities
4 Members
0 Resources
23 MeSH Terms
The Goldilocks effect.
Boothby M, Williams CL
(2012) Sci Transl Med 4: 163fs42
MeSH Terms: Animals, Humans, Methyl-CpG-Binding Protein 2, Th1 Cells
Added December 10, 2013
0 Communities
1 Members
0 Resources
4 MeSH Terms
Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2.
Young JI, Hong EP, Castle JC, Crespo-Barreto J, Bowman AB, Rose MF, Kang D, Richman R, Johnson JM, Berget S, Zoghbi HY
(2005) Proc Natl Acad Sci U S A 102: 17551-8
MeSH Terms: Animals, Cell Line, Tumor, DNA Methylation, Exons, Gene Expression Profiling, Genes, Reporter, Humans, Methyl-CpG-Binding Protein 2, Mice, Models, Genetic, Protein Binding, RNA, RNA Splicing, Rett Syndrome, Transcription, Genetic
Added June 9, 2010
1 Communities
1 Members
0 Resources
15 MeSH Terms
T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-site.
Tong Y, Aune T, Boothby M
(2005) Proc Natl Acad Sci U S A 102: 2034-9
MeSH Terms: Binding Sites, CCAAT-Enhancer-Binding Proteins, Chromosomal Proteins, Non-Histone, DNA Methylation, DNA-Binding Proteins, Epigenesis, Genetic, Humans, Interferon-gamma, Jurkat Cells, Methyl-CpG-Binding Protein 2, Promoter Regions, Genetic, Repressor Proteins, Sin3 Histone Deacetylase and Corepressor Complex, T-Box Domain Proteins, Transcription Factors, Transcriptional Activation
Added December 10, 2013
0 Communities
2 Members
0 Resources
16 MeSH Terms