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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 19

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Methamphetamine-induced toxicity: an updated review on issues related to hyperthermia.
Matsumoto RR, Seminerio MJ, Turner RC, Robson MJ, Nguyen L, Miller DB, O'Callaghan JP
(2014) Pharmacol Ther 144: 28-40
MeSH Terms: Animals, Body Temperature, Body Temperature Regulation, Central Nervous System Stimulants, Dopamine, Drug Overdose, Fever, Humans, Methamphetamine
Added August 26, 2015
0 Communities
1 Members
0 Resources
9 MeSH Terms
SN79, a sigma receptor antagonist, attenuates methamphetamine-induced astrogliosis through a blockade of OSMR/gp130 signaling and STAT3 phosphorylation.
Robson MJ, Turner RC, Naser ZJ, McCurdy CR, O'Callaghan JP, Huber JD, Matsumoto RR
(2014) Exp Neurol 254: 180-9
MeSH Terms: Animals, Astrocytes, Benzoxazoles, Central Nervous System Stimulants, Corpus Striatum, Cytokine Receptor gp130, Dopaminergic Neurons, Drug Interactions, Fever, Glial Fibrillary Acidic Protein, Gliosis, Male, Methamphetamine, Mice, Oncostatin M Receptor beta Subunit, Phosphorylation, Piperazines, Receptors, sigma, STAT3 Transcription Factor, Signal Transduction
Added August 26, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Sigma (σ) receptors as potential therapeutic targets to mitigate psychostimulant effects.
Matsumoto RR, Nguyen L, Kaushal N, Robson MJ
(2014) Adv Pharmacol 69: 323-86
MeSH Terms: Animals, Central Nervous System Stimulants, Clinical Trials as Topic, Cocaine, Drug Delivery Systems, Humans, Methamphetamine, Opipramol, Protein Binding, Receptors, sigma, Substance-Related Disorders
Added August 26, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Neuroprotective targets through which 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a sigma receptor ligand, mitigates the effects of methamphetamine in vitro.
Kaushal N, Robson MJ, Rosen A, McCurdy CR, Matsumoto RR
(2014) Eur J Pharmacol 724: 193-203
MeSH Terms: Animals, Apoptosis, Benzoxazoles, Caspases, Cell Line, Tumor, Fever, Ligands, Methamphetamine, Mice, Necrosis, Neuroprotective Agents, Piperazines, Reactive Nitrogen Species, Reactive Oxygen Species, Receptors, sigma, eIF-2 Kinase
Added August 26, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
The complex relationship between the light-entrainable and methamphetamine-sensitive circadian oscillators: evidence from behavioral studies of Period-mutant mice.
Pendergast JS, Niswender KD, Yamazaki S
(2013) Eur J Neurosci 38: 3044-53
MeSH Terms: Animals, Central Nervous System Stimulants, Circadian Rhythm, Female, Light, Male, Methamphetamine, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, Motor Activity, Period Circadian Proteins, Suprachiasmatic Nucleus
Added February 19, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
σ Receptor antagonist attenuation of methamphetamine-induced neurotoxicity is correlated to body temperature modulation.
Robson MJ, Seminerio MJ, McCurdy CR, Coop A, Matsumoto RR
(2013) Pharmacol Rep 65: 343-9
MeSH Terms: Animals, Benzothiazoles, Body Temperature, Corpus Striatum, Dopamine, Dopamine Agents, Fever, Male, Methamphetamine, Mice, Neurotoxicity Syndromes, Oxalates, Piperazines, Piperidines, Receptors, sigma
Added July 10, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms
Bupropion, methylphenidate, and 3,4-methylenedioxypyrovalerone antagonize methamphetamine-induced efflux of dopamine according to their potencies as dopamine uptake inhibitors: implications for the treatment of methamphetamine dependence.
Simmler LD, Wandeler R, Liechti ME
(2013) BMC Res Notes 6: 220
MeSH Terms: Amphetamine-Related Disorders, Benzodioxoles, Biological Transport, Bupropion, Dopamine, Humans, Methamphetamine, Methylphenidate, Pyrrolidines
Added August 3, 2013
0 Communities
1 Members
0 Resources
9 MeSH Terms
SN79, a sigma receptor ligand, blocks methamphetamine-induced microglial activation and cytokine upregulation.
Robson MJ, Turner RC, Naser ZJ, McCurdy CR, Huber JD, Matsumoto RR
(2013) Exp Neurol 247: 134-42
MeSH Terms: Analysis of Variance, Animals, Antigens, CD, Antigens, Differentiation, Myelomonocytic, Benzoxazoles, Body Temperature, Brain, Cytokines, Male, Methamphetamine, Mice, Microglia, Piperazines, RNA, Messenger, Receptors, sigma, Time Factors, Up-Regulation
Added July 10, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Chronic methamphetamine exposure produces a delayed, long-lasting memory deficit.
North A, Swant J, Salvatore MF, Gamble-George J, Prins P, Butler B, Mittal MK, Heltsley R, Clark JT, Khoshbouei H
(2013) Synapse 67: 245-57
MeSH Terms: Age Factors, Animals, Dopamine Agents, Hippocampus, Long-Term Potentiation, Male, Memory, Short-Term, Methamphetamine, Mice, Mice, Inbred C57BL, Time Factors
Added July 10, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Pharmacological evaluation of SN79, a sigma (σ) receptor ligand, against methamphetamine-induced neurotoxicity in vivo.
Kaushal N, Seminerio MJ, Robson MJ, McCurdy CR, Matsumoto RR
(2013) Eur Neuropsychopharmacol 23: 960-71
MeSH Terms: Animals, Benzoxazoles, Central Nervous System Stimulants, Corpus Striatum, Dopamine, Dopamine Antagonists, Dopamine Plasma Membrane Transport Proteins, Drug Synergism, Fever, Guanidines, Male, Methamphetamine, Mice, Nerve Tissue Proteins, Neurons, Neuroprotective Agents, Neurotoxicity Syndromes, Piperazines, Random Allocation, Receptors, sigma, Serotonin, Serotonin Antagonists, Serotonin Plasma Membrane Transport Proteins
Added July 10, 2013
0 Communities
1 Members
0 Resources
23 MeSH Terms