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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 18

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Vitamin E does not prevent Western diet-induced NASH progression and increases metabolic flux dysregulation in mice.
Hasenour CM, Kennedy AJ, Bednarski T, Trenary IA, Eudy BJ, da Silva RP, Boyd KL, Young JD
(2020) J Lipid Res 61: 707-721
MeSH Terms: Animals, Antioxidants, Diet, Western, Drug Interactions, Lipid Metabolism, Liver, Male, Metabolic Flux Analysis, Mice, Non-alcoholic Fatty Liver Disease, Solubility, Vitamin E
Added March 5, 2020
0 Communities
1 Members
0 Resources
12 MeSH Terms
Metabolic network-based predictions of toxicant-induced metabolite changes in the laboratory rat.
Pannala VR, Wall ML, Estes SK, Trenary I, O'Brien TP, Printz RL, Vinnakota KC, Reifman J, Shiota M, Young JD, Wallqvist A
(2018) Sci Rep 8: 11678
MeSH Terms: Acetaminophen, Animals, Animals, Laboratory, Gene Expression Regulation, Glycogenolysis, Liver, Male, Metabolic Flux Analysis, Metabolic Networks and Pathways, Metabolome, Pyruvates, Rats, Sprague-Dawley
Added March 28, 2019
0 Communities
1 Members
0 Resources
12 MeSH Terms
Glycine -methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates.
Hughey CC, Trefts E, Bracy DP, James FD, Donahue EP, Wasserman DH
(2018) J Biol Chem 293: 11944-11954
MeSH Terms: Animals, Carbon, Citric Acid Cycle, Energy Metabolism, Fatty Liver, Gene Deletion, Gluconeogenesis, Glucose, Glycine N-Methyltransferase, Liver, Male, Metabolic Flux Analysis, Methionine, Mice, Mice, Knockout, S-Adenosylmethionine
Added March 26, 2019
1 Communities
0 Members
0 Resources
MeSH Terms
Isotopically nonstationary metabolic flux analysis (INST-MFA): putting theory into practice.
Cheah YE, Young JD
(2018) Curr Opin Biotechnol 54: 80-87
MeSH Terms: Autotrophic Processes, Carbon Isotopes, Isotope Labeling, Metabolic Flux Analysis, Models, Biological, Software
Added March 14, 2018
0 Communities
1 Members
0 Resources
6 MeSH Terms
C Flux Analysis Reveals that Rebalancing Medium Amino Acid Composition can Reduce Ammonia Production while Preserving Central Carbon Metabolism of CHO Cell Cultures.
McAtee Pereira AG, Walther JL, Hollenbach M, Young JD
(2018) Biotechnol J 13: e1700518
MeSH Terms: Amino Acids, Ammonia, Animals, Antibodies, Monoclonal, CHO Cells, Carbon, Cricetulus, Culture Media, Glycosylation, Metabolic Flux Analysis, Recombinant Proteins
Added March 14, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms
Isotopically Nonstationary Metabolic Flux Analysis (INST-MFA) of Photosynthesis and Photorespiration in Plants.
Ma F, Jazmin LJ, Young JD, Allen DK
(2017) Methods Mol Biol 1653: 167-194
MeSH Terms: Amino Acids, Arabidopsis, Carbon Dioxide, Carbon Isotopes, Chlorophyll, Chloroplasts, Isotope Labeling, Mass Spectrometry, Metabolic Flux Analysis, Metabolic Networks and Pathways, Oxygen, Oxygen Consumption, Photosynthesis, Plant Leaves, Ribulose-Bisphosphate Carboxylase, Starch, Sucrose
Added September 11, 2017
0 Communities
1 Members
0 Resources
17 MeSH Terms
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.
Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD
(2017) Cell Metab 25: 838-855.e15
MeSH Terms: Amidohydrolases, Amino Acid Sequence, Animals, Carbon-Carbon Ligases, Glucose, HEK293 Cells, Homeostasis, Humans, Insulin, Insulin Resistance, Insulin Secretion, Leucine, Lysine, Metabolic Flux Analysis, Mice, Inbred C57BL, Mice, Knockout, Mitochondrial Proteins, Models, Molecular, Phylogeny, Sirtuins
Added April 18, 2017
0 Communities
1 Members
0 Resources
20 MeSH Terms
Modeling Method for Increased Precision and Scope of Directly Measurable Fluxes at a Genome-Scale.
McCloskey D, Young JD, Xu S, Palsson BO, Feist AM
(2016) Anal Chem 88: 3844-52
MeSH Terms: Carbon Isotopes, Escherichia coli, Genome, Bacterial, Metabolic Flux Analysis, Models, Biological
Added March 31, 2016
0 Communities
1 Members
0 Resources
5 MeSH Terms
MID Max: LC-MS/MS Method for Measuring the Precursor and Product Mass Isotopomer Distributions of Metabolic Intermediates and Cofactors for Metabolic Flux Analysis Applications.
McCloskey D, Young JD, Xu S, Palsson BO, Feist AM
(2016) Anal Chem 88: 1362-70
MeSH Terms: Adenosine Triphosphate, Carbohydrate Metabolism, Chromatography, High Pressure Liquid, Escherichia coli, Isotope Labeling, Metabolic Flux Analysis, Molecular Structure, Tandem Mass Spectrometry
Added March 31, 2016
0 Communities
1 Members
0 Resources
8 MeSH Terms
(13)C metabolic flux analysis of recombinant expression hosts.
Young JD
(2014) Curr Opin Biotechnol 30: 238-45
MeSH Terms: Carbon Isotopes, Glucose, Industrial Microbiology, Metabolic Flux Analysis, Metabolic Networks and Pathways, Recombinant Proteins, Software
Added January 23, 2015
0 Communities
1 Members
0 Resources
7 MeSH Terms