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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 41

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Biologic comparison of inhaled insulin formulations: Exubera™ and novel spray-dried engineered particles of dextran-10.
Kuehl PJ, Cherrington A, Dobry DE, Edgerton D, Friesen DT, Hobbs C, Leach CL, Murri B, Neal D, Lyon DK, Vodak DT, Reed MD
(2014) AAPS PharmSciTech 15: 1545-50
MeSH Terms: Administration, Inhalation, Aerosols, Animals, Area Under Curve, Blood Glucose, Chemistry, Pharmaceutical, Cross-Over Studies, Dextrans, Dogs, Drug Carriers, Female, Hypoglycemic Agents, Insulin, Metabolic Clearance Rate, Particle Size, Powders, Technology, Pharmaceutical
Added February 12, 2015
0 Communities
2 Members
0 Resources
17 MeSH Terms
Pharmacokinetics and pharmacodynamics of imipenem and meropenem in critically ill patients treated with continuous venovenous hemodialysis.
Afshartous D, Bauer SR, Connor MJ, Aduroja OA, Amde M, Salem C, Groszek JJ, Fissell WH
(2014) Am J Kidney Dis 63: 170-1
MeSH Terms: Anti-Bacterial Agents, Critical Illness, Drug Dosage Calculations, Female, Gram-Negative Bacterial Infections, Humans, Imipenem, Male, Medication Errors, Meropenem, Metabolic Clearance Rate, Middle Aged, Renal Dialysis, Thienamycins
Added February 25, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Clinical and genetic determinants of plasma nevirapine exposure following an intrapartum dose to prevent mother-to-child HIV transmission.
Vardhanabhuti S, Acosta EP, Ribaudo HJ, Severe P, Lalloo U, Kumarasamy N, Taulo F, Kabanda J, Oneko O, Ive P, Sambarey P, Chan ES, Hitti J, Hong F, McMahon D, Haas DW, A5207 ACTG Study Team
(2013) J Infect Dis 208: 662-71
MeSH Terms: Adult, Anti-HIV Agents, Aryl Hydrocarbon Hydroxylases, Chemoprevention, Cytochrome P-450 CYP2B6, Female, HIV Infections, Humans, Infant, Newborn, Infectious Disease Transmission, Vertical, Inhibitory Concentration 50, Male, Metabolic Clearance Rate, Nevirapine, Oxidoreductases, N-Demethylating, Plasma, Polymorphism, Genetic, Pregnancy, Time Factors, Young Adult
Added March 13, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Safety, pharmacokinetics and pharmacodynamics of the anti-A33 fully-human monoclonal antibody, KRN330, in patients with advanced colorectal cancer.
Infante JR, Bendell JC, Goff LW, Jones SF, Chan E, Sudo T, Burris HA, Berlin JD
(2013) Eur J Cancer 49: 1169-75
MeSH Terms: Adult, Aged, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Area Under Curve, Colorectal Neoplasms, Diarrhea, Dose-Response Relationship, Drug, Drug Administration Schedule, Drug Resistance, Neoplasm, Female, Humans, Immunohistochemistry, Male, Membrane Glycoproteins, Metabolic Clearance Rate, Middle Aged, Nausea, Neoplasm Metastasis, Time Factors, Treatment Outcome, Vomiting
Added March 11, 2014
0 Communities
2 Members
0 Resources
22 MeSH Terms
Antimicrobial dosing in acute renal replacement.
Fissell WH
(2013) Adv Chronic Kidney Dis 20: 85-93
MeSH Terms: Acute Kidney Injury, Anti-Bacterial Agents, Antifungal Agents, Biological Availability, Critical Care, Critical Illness, Drug Administration Schedule, Drug Dosage Calculations, Humans, Inactivation, Metabolic, Metabolic Clearance Rate, Piperacillin, Practice Guidelines as Topic, Renal Replacement Therapy, Tissue Distribution
Added August 21, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms
The role of aldehyde oxidase and xanthine oxidase in the biotransformation of a novel negative allosteric modulator of metabotropic glutamate receptor subtype 5.
Morrison RD, Blobaum AL, Byers FW, Santomango TS, Bridges TM, Stec D, Brewer KA, Sanchez-Ponce R, Corlew MM, Rush R, Felts AS, Manka J, Bates BS, Venable DF, Rodriguez AL, Jones CK, Niswender CM, Conn PJ, Lindsley CW, Emmitte KA, Daniels JS
(2012) Drug Metab Dispos 40: 1834-45
MeSH Terms: Aldehyde Oxidase, Allopurinol, Animals, Benzamides, Biotransformation, Chromatography, Liquid, Enzyme Inhibitors, Excitatory Amino Acid Antagonists, Hepatocytes, Humans, Hydroxylation, Injections, Intravenous, Liver, Macaca fascicularis, Magnetic Resonance Spectroscopy, Male, Metabolic Clearance Rate, Microsomes, Liver, Models, Biological, Molecular Structure, Oxygen Isotopes, Raloxifene Hydrochloride, Rats, Rats, Sprague-Dawley, Receptor, Metabotropic Glutamate 5, Receptors, Metabotropic Glutamate, Species Specificity, Tandem Mass Spectrometry, Thiazoles, Xanthine Oxidase
Added March 7, 2014
1 Communities
5 Members
0 Resources
30 MeSH Terms
Novel dialysis modalities: do we need new metrics to optimize treatment?
Fissell R, Schulman G, Pfister M, Zhang L, Hung AM
(2012) J Clin Pharmacol 52: 72S-8S
MeSH Terms: Humans, Metabolic Clearance Rate, Renal Dialysis
Added March 21, 2014
0 Communities
1 Members
0 Resources
3 MeSH Terms
Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans.
Haas DW, Gebretsadik T, Mayo G, Menon UN, Acosta EP, Shintani A, Floyd M, Stein CM, Wilkinson GR
(2009) J Infect Dis 199: 872-80
MeSH Terms: African Continental Ancestry Group, Alkynes, Anti-HIV Agents, Area Under Curve, Aryl Hydrocarbon Hydroxylases, Benzoxazines, Cyclopropanes, Cytochrome P-450 CYP2B6, Genotype, HIV Seronegativity, Humans, Linkage Disequilibrium, Metabolic Clearance Rate, Nevirapine, Oxidoreductases, N-Demethylating, Polymorphism, Genetic, Safety
Added March 13, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe.
Urquhart BL, Ware JA, Tirona RG, Ho RH, Leake BF, Schwarz UI, Zaher H, Palandra J, Gregor JC, Dresser GK, Kim RB
(2008) Pharmacogenet Genomics 18: 439-48
MeSH Terms: ATP Binding Cassette Transporter, Subfamily G, Member 2, ATP-Binding Cassette Transporters, Adolescent, Adult, Caco-2 Cells, Drug Resistance, Neoplasm, Female, Gastrointestinal Agents, HeLa Cells, Humans, Inactivation, Metabolic, Intestinal Mucosa, Male, Metabolic Clearance Rate, Middle Aged, Neoplasm Proteins, Polymorphism, Single Nucleotide, Sulfasalazine, Tissue Distribution
Added March 5, 2014
2 Communities
2 Members
0 Resources
19 MeSH Terms
Vigorous motor activity in Caenorhabditis elegans requires efficient clearance of dopamine mediated by synaptic localization of the dopamine transporter DAT-1.
McDonald PW, Hardie SL, Jessen TN, Carvelli L, Matthies DS, Blakely RD
(2007) J Neurosci 27: 14216-27
MeSH Terms: Animals, Animals, Genetically Modified, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Cell Line, Dopamine, Dopamine Plasma Membrane Transport Proteins, Humans, Male, Metabolic Clearance Rate, Motor Activity, Synapses
Added July 10, 2013
1 Communities
1 Members
0 Resources
12 MeSH Terms