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A GRM7 mutation associated with developmental delay reduces mGlu7 expression and produces neurological phenotypes.
Fisher NM, AlHashim A, Buch AB, Badivuku H, Samman MM, Weiss KM, Cestero GI, Does MD, Rook JM, Lindsley CW, Conn PJ, Gogliotti RG, Niswender CM
(2021) JCI Insight 6:
MeSH Terms: Animals, Autism Spectrum Disorder, Child, Child, Preschool, Epilepsy, Fear, Female, GTP-Binding Proteins, Genetic Predisposition to Disease, Humans, Infant, Learning, Male, Mice, Mice, Inbred C57BL, Mutation, Neurodevelopmental Disorders, Pedigree, Phenotype, Receptors, Metabotropic Glutamate, Seizures
Added January 29, 2021
1 Communities
0 Members
0 Resources
21 MeSH Terms
Mental health conditions and the risk of chronic opioid therapy among patients with rheumatoid arthritis: a retrospective veterans affairs cohort study.
Liberman JS, D'Agostino McGowan L, Greevy RA, Morrow JA, Griffin MR, Roumie CL, Grijalva CG
(2020) Clin Rheumatol 39: 1793-1802
MeSH Terms: Aged, Analgesics, Opioid, Arthritis, Rheumatoid, Chronic Pain, Databases, Factual, Female, Humans, Male, Mental Disorders, Middle Aged, Multivariate Analysis, Opioid-Related Disorders, Prescription Drugs, Proportional Hazards Models, Retrospective Studies, Risk Factors, United States, Veterans
Added March 29, 2022
0 Communities
1 Members
0 Resources
MeSH Terms
An anthrone-based Kv7.2/7.3 channel blocker with improved properties for the investigation of psychiatric and neurodegenerative disorders.
Porter JD, Vivas O, Weaver CD, Alsafran A, DiMilo E, Arnold LA, Dickson EJ, Dockendorff C
(2019) Bioorg Med Chem Lett 29: 126681
MeSH Terms: Anthracenes, Dose-Response Relationship, Drug, KCNQ2 Potassium Channel, KCNQ3 Potassium Channel, Mental Disorders, Molecular Structure, Neurodegenerative Diseases, Potassium Channel Blockers, Structure-Activity Relationship
Added March 27, 2020
0 Communities
1 Members
0 Resources
9 MeSH Terms
Psychiatry's Obligation to Treat and Mitigate the Rising Burden of Age-Related Mental Disorders.
Taylor WD, Reynolds CF
(2020) JAMA Psychiatry 77: 5-6
MeSH Terms: Age Factors, Aged, Cost of Illness, Humans, Mental Disorders, Psychiatry, Social Responsibility, United States
Added March 3, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
Multi-tissue transcriptome analyses identify genetic mechanisms underlying neuropsychiatric traits.
Gamazon ER, Zwinderman AH, Cox NJ, Denys D, Derks EM
(2019) Nat Genet 51: 933-940
MeSH Terms: Algorithms, Computational Biology, Gene Expression Profiling, Gene Expression Regulation, Gene Regulatory Networks, Genetic Association Studies, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Mental Disorders, Organ Specificity, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Quantitative Trait, Heritable, Transcriptome
Added July 17, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
A Hierarchical Taxonomy of Psychopathology Can Transform Mental Health Research.
Conway CC, Forbes MK, Forbush KT, Fried EI, Hallquist MN, Kotov R, Mullins-Sweatt SN, Shackman AJ, Skodol AE, South SC, Sunderland M, Waszczuk MA, Zald DH, Afzali MH, Bornovalova MA, Carragher N, Docherty AR, Jonas KG, Krueger RF, Patalay P, Pincus AL, Tackett JL, Reininghaus U, Waldman ID, Wright AGC, Zimmermann J, Bach B, Bagby RM, Chmielewski M, Cicero DC, Clark LA, Dalgleish T, DeYoung CG, Hopwood CJ, Ivanova MY, Latzman RD, Patrick CJ, Ruggero CJ, Samuel DB, Watson D, Eaton NR
(2019) Perspect Psychol Sci 14: 419-436
MeSH Terms: Heuristics, Humans, Mental Disorders, Models, Theoretical, Research Design, Terminology as Topic
Added April 15, 2019
0 Communities
1 Members
0 Resources
6 MeSH Terms
Individual Differences in Dopamine Are Associated with Reward Discounting in Clinical Groups But Not in Healthy Adults.
Castrellon JJ, Seaman KL, Crawford JL, Young JS, Smith CT, Dang LC, Hsu M, Cowan RL, Zald DH, Samanez-Larkin GR
(2019) J Neurosci 39: 321-332
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, Aging, Behavior, Addictive, Brain, Brain Mapping, Delay Discounting, Dopamine, Female, Humans, Individuality, Male, Mental Disorders, Middle Aged, Positron-Emission Tomography, Receptors, Dopamine D2, Reward, Young Adult
Added April 15, 2019
0 Communities
1 Members
0 Resources
20 MeSH Terms
Neurological symptoms in Hypophosphatasia.
Colazo JM, Hu JR, Dahir KM, Simmons JH
(2019) Osteoporos Int 30: 469-480
MeSH Terms: Adolescent, Adult, Aged, Alkaline Phosphatase, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Hypophosphatasia, Male, Mental Disorders, Middle Aged, Nervous System Diseases, Prevalence, Retrospective Studies, United States, Vitamin B 6, Young Adult
Added April 6, 2019
0 Communities
1 Members
0 Resources
19 MeSH Terms
Irritability, Externalizing, and Internalizing Psychopathology in Adolescence: Cross-Sectional and Longitudinal Associations and Moderation by Sex.
Humphreys KL, Schouboe SNF, Kircanski K, Leibenluft E, Stringaris A, Gotlib IH
(2019) J Clin Child Adolesc Psychol 48: 781-789
MeSH Terms: Adolescent, Adult, Child, Cross-Sectional Studies, Female, Humans, Irritable Mood, Longitudinal Studies, Male, Mental Disorders, Psychopathology, Sex Factors, Young Adult
Added March 3, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
Neurodevelopmental considerations in surgical necrotizing enterocolitis.
Robinson JR, Kennedy C, van Arendonk KJ, Green A, Martin CR, Blakely ML
(2018) Semin Pediatr Surg 27: 52-56
MeSH Terms: Enterocolitis, Necrotizing, Humans, Infant, Newborn, Infant, Premature, Infant, Premature, Diseases, Neurodevelopmental Disorders, Neuropsychological Tests, Postoperative Complications
Added June 27, 2018
0 Communities
1 Members
0 Resources
MeSH Terms