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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 157

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A KCNK16 mutation causing TALK-1 gain of function is associated with maturity-onset diabetes of the young.
Graff SM, Johnson SR, Leo PJ, Dadi PK, Dickerson MT, Nakhe AY, McInerney-Leo AM, Marshall M, Zaborska KE, Schaub CM, Brown MA, Jacobson DA, Duncan EL
(2021) JCI Insight 6:
MeSH Terms: Animals, Blood Glucose, Calcium Signaling, Channelopathies, Diabetes Mellitus, Type 2, Gain of Function Mutation, Humans, Insulin Secretion, Insulin-Secreting Cells, Membrane Potentials, Mice, Potassium Channels, Tandem Pore Domain
Added June 14, 2021
0 Communities
1 Members
0 Resources
12 MeSH Terms
Lactate activation of α-cell K channels inhibits glucagon secretion by hyperpolarizing the membrane potential and reducing Ca entry.
Zaborska KE, Dadi PK, Dickerson MT, Nakhe AY, Thorson AS, Schaub CM, Graff SM, Stanley JE, Kondapavuluru RS, Denton JS, Jacobson DA
(2020) Mol Metab 42: 101056
MeSH Terms: Animals, Calcium, Cell Line, Cell Membrane, Glucagon, Glucagon-Secreting Cells, Glucose, Humans, Islets of Langerhans, KATP Channels, Lactic Acid, Male, Membrane Potentials, Mice, Mice, Inbred C57BL, Mice, Transgenic, Pancreas, Primary Cell Culture, Pyruvic Acid
Added June 14, 2021
0 Communities
1 Members
0 Resources
19 MeSH Terms
Androgenic effects on ventricular repolarization: A translational study from the international pharmacovigilance database to iPSC-cardiomyocytes.
Salem JE, Yang T, Moslehi JJ, Waintraub X, Gandjbakhch E, Bachelot A, Hidden-Lucet F, Hulot JS, Knollmann BC, Lebrun-Vignes B, Funck-Brentano C, Glazer AM, Roden DM
(2021) Ann Endocrinol (Paris) 82: 132-133
MeSH Terms: Androgens, Cell Differentiation, Cells, Cultured, Databases, Factual, Death, Sudden, Cardiac, Dihydrotestosterone, Electrophysiological Phenomena, Eunuchism, Heart Ventricles, Humans, Induced Pluripotent Stem Cells, Internationality, Long QT Syndrome, Male, Membrane Potentials, Myocytes, Cardiac, Pharmacovigilance, Torsades de Pointes, Translational Research, Biomedical, Ventricular Function
Added March 24, 2020
0 Communities
2 Members
0 Resources
20 MeSH Terms
Chronic Intermittent Ethanol and Acute Stress Similarly Modulate BNST CRF Neuron Activity via Noradrenergic Signaling.
Snyder AE, Salimando GJ, Winder DG, Silberman Y
(2019) Alcohol Clin Exp Res 43: 1695-1701
MeSH Terms: Adrenergic Neurons, Animals, Corticotropin-Releasing Hormone, Ethanol, Excitatory Amino Acid Antagonists, Gene Knock-In Techniques, Glutamic Acid, Kynurenic Acid, Male, Membrane Potentials, Mice, Norepinephrine, Picrotoxin, Propranolol, Restraint, Physical, Septal Nuclei, Substance Withdrawal Syndrome
Added March 30, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
Electrophysiologic and molecular mechanisms of a frameshift NPPA mutation linked with familial atrial fibrillation.
Menon A, Hong L, Savio-Galimberti E, Sridhar A, Youn SW, Zhang M, Kor K, Blair M, Kupershmidt S, Darbar D
(2019) J Mol Cell Cardiol 132: 24-35
MeSH Terms: Action Potentials, Animals, Atrial Fibrillation, Atrial Natriuretic Factor, Electrophysiological Phenomena, Frameshift Mutation, Heart Atria, Humans, Membrane Potentials, Mice, Mice, Transgenic, Myocytes, Cardiac, NAV1.5 Voltage-Gated Sodium Channel
Added June 14, 2019
1 Communities
0 Members
0 Resources
13 MeSH Terms
Late onset obesity in mice with targeted deletion of potassium inward rectifier Kir7.1 from cells expressing the melanocortin-4 receptor.
Anderson EJP, Ghamari-Langroudi M, Cakir I, Litt MJ, Chen V, Reggiardo RE, Millhauser GL, Cone RD
(2019) J Neuroendocrinol 31: e12670
MeSH Terms: Animals, Feeding Behavior, Female, Hypothalamus, Male, Membrane Potentials, Mice, Inbred C57BL, Mice, Knockout, Neurons, Obesity, Potassium Channels, Inwardly Rectifying, Receptor, Melanocortin, Type 4
Added January 8, 2019
1 Communities
0 Members
0 Resources
12 MeSH Terms
Simultaneous Real-Time Measurement of the β-Cell Membrane Potential and Ca Influx to Assess the Role of Potassium Channels on β-Cell Function.
Vierra NC, Dickerson MT, Philipson LH, Jacobson DA
(2018) Methods Mol Biol 1684: 73-84
MeSH Terms: Animals, Calcium, Cells, Cultured, Humans, Insulin-Secreting Cells, Membrane Potentials, Mice, Patch-Clamp Techniques, Potassium Channels
Added November 13, 2017
0 Communities
1 Members
0 Resources
9 MeSH Terms
Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells.
Dickerson MT, Vierra NC, Milian SC, Dadi PK, Jacobson DA
(2017) PLoS One 12: e0175069
MeSH Terms: Aged, Animals, Calcium Signaling, Diabetes Mellitus, Type 2, Female, Glucose, HEK293 Cells, Humans, Insulin, Insulin Secretion, Insulin-Secreting Cells, Membrane Potentials, Mice, Knockout, Osteopontin, Potassium, Potassium Channels, Tandem Pore Domain
Added November 13, 2017
0 Communities
1 Members
0 Resources
16 MeSH Terms
An interplay between the serotonin transporter (SERT) and 5-HT receptors controls stimulus-secretion coupling in sympathoadrenal chromaffin cells.
Brindley RL, Bauer MB, Blakely RD, Currie KPM
(2016) Neuropharmacology 110: 438-448
MeSH Terms: Adrenal Glands, Animals, Calcium, Calcium Channels, N-Type, Cations, Divalent, Cells, Cultured, Chromaffin Cells, Exocytosis, Male, Membrane Potentials, Mice, Inbred C57BL, Mice, Knockout, Potassium Channels, Voltage-Gated, Receptors, Serotonin, Serotonin, Serotonin Agents, Serotonin Plasma Membrane Transport Proteins
Added August 22, 2016
0 Communities
1 Members
0 Resources
17 MeSH Terms
Comparison of γ-Aminobutyric Acid, Type A (GABAA), Receptor αβγ and αβδ Expression Using Flow Cytometry and Electrophysiology: EVIDENCE FOR ALTERNATIVE SUBUNIT STOICHIOMETRIES AND ARRANGEMENTS.
Botzolakis EJ, Gurba KN, Lagrange AH, Feng HJ, Stanic AK, Hu N, Macdonald RL
(2016) J Biol Chem 291: 20440-61
MeSH Terms: Epilepsy, Flow Cytometry, Gene Expression Regulation, HEK293 Cells, Humans, Membrane Potentials, Protein Subunits, Receptors, GABA
Added March 14, 2018
0 Communities
1 Members
0 Resources
8 MeSH Terms