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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 296

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Evolving insights into the mechanisms of toxicity associated with immune checkpoint inhibitor therapy.
Mangan BL, McAlister RK, Balko JM, Johnson DB, Moslehi JJ, Gibson A, Phillips EJ
(2020) Br J Clin Pharmacol 86: 1778-1789
MeSH Terms: Drug-Related Side Effects and Adverse Reactions, Humans, Immune Checkpoint Inhibitors, Incidence, Melanoma, Neoplasms, Programmed Cell Death 1 Receptor
Added September 29, 2020
0 Communities
1 Members
0 Resources
7 MeSH Terms
Demographic Factors Associated with Toxicity in Patients Treated with Anti-Programmed Cell Death-1 Therapy.
Shah KP, Song H, Ye F, Moslehi JJ, Balko JM, Salem JE, Johnson DB
(2020) Cancer Immunol Res 8: 851-855
MeSH Terms: Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Antineoplastic Agents, Immunological, CTLA-4 Antigen, Female, Hospitalization, Humans, Immunologic Factors, Immunotherapy, Length of Stay, Male, Melanoma, Middle Aged, Programmed Cell Death 1 Receptor, Risk Factors, Young Adult
Added May 29, 2020
0 Communities
1 Members
0 Resources
19 MeSH Terms
Multimodal Multiplexed Immunoimaging with Nanostars to Detect Multiple Immunomarkers and Monitor Response to Immunotherapies.
Ou YC, Wen X, Johnson CA, Shae D, Ayala OD, Webb JA, Lin EC, DeLapp RC, Boyd KL, Richmond A, Mahadevan-Jansen A, Rafat M, Wilson JT, Balko JM, Tantawy MN, Vilgelm AE, Bardhan R
(2020) ACS Nano 14: 651-663
MeSH Terms: Animals, B7-H1 Antigen, Biomarkers, Tumor, Cell Line, Tumor, Disease Models, Animal, Gold, Immunotherapy, Melanoma, Metal Nanoparticles, Mice, Optical Imaging, Particle Size, Surface Properties, Tumor Necrosis Factor Receptor Superfamily, Member 9
Added March 17, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21.
Vilgelm AE, Saleh N, Shattuck-Brandt R, Riemenschneider K, Slesur L, Chen SC, Johnson CA, Yang J, Blevins A, Yan C, Johnson DB, Al-Rohil RN, Halilovic E, Kauffmann RM, Kelley M, Ayers GD, Richmond A
(2019) Sci Transl Med 11:
MeSH Terms: Analysis of Variance, Animals, Blotting, Western, Cell Cycle, Cell Survival, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, Cyclin-Dependent Kinase Inhibitor p21, DNA Replication, Dimethyl Sulfoxide, Humans, Immunoprecipitation, MCF-7 Cells, Melanoma, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Nude, Proteomics, Proto-Oncogene Proteins c-mdm2, Radioimmunoprecipitation Assay
Added September 27, 2019
0 Communities
1 Members
0 Resources
21 MeSH Terms
Identification of Targetable Recurrent MAP3K8 Rearrangements in Melanomas Lacking Known Driver Mutations.
Lehmann BD, Shaver TM, Johnson DB, Li Z, Gonzalez-Ericsson PI, Sánchez V, Shyr Y, Sanders ME, Pietenpol JA
(2019) Mol Cancer Res 17: 1842-1853
MeSH Terms: Algorithms, Cell Line, Tumor, Databases, Genetic, Female, Gene Amplification, Gene Expression Regulation, Neoplastic, Humans, MAP Kinase Kinase Kinases, Male, Melanoma, Protein Kinase Inhibitors, Proto-Oncogene Proteins, Sequence Analysis, RNA, Sequence Deletion, Survival Analysis, Translocation, Genetic, Up-Regulation
Added March 30, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
Quantifying Drug Combination Synergy along Potency and Efficacy Axes.
Meyer CT, Wooten DJ, Paudel BB, Bauer J, Hardeman KN, Westover D, Lovly CM, Harris LA, Tyson DR, Quaranta V
(2019) Cell Syst 8: 97-108.e16
MeSH Terms: Drug Combinations, Drug Synergism, Humans, Melanoma
Added March 23, 2019
0 Communities
3 Members
0 Resources
4 MeSH Terms
Response to Anti-PD-1 in Uveal Melanoma Without High-Volume Liver Metastasis.
Johnson DB, Bao R, Ancell KK, Daniels AB, Wallace D, Sosman JA, Luke JJ
(2019) J Natl Compr Canc Netw 17: 114-117
MeSH Terms: Antineoplastic Agents, Immunological, Computational Biology, Gene Expression Profiling, Humans, Liver Neoplasms, Melanoma, Molecular Targeted Therapy, Neoplasm Staging, Prognosis, Programmed Cell Death 1 Receptor, Treatment Outcome, Uveal Neoplasms
Added March 30, 2020
0 Communities
1 Members
0 Resources
12 MeSH Terms
Impaired enolase 1 glycolytic activity restrains effector functions of tumor-infiltrating CD8 T cells.
Gemta LF, Siska PJ, Nelson ME, Gao X, Liu X, Locasale JW, Yagita H, Slingluff CL, Hoehn KL, Rathmell JC, Bullock TNJ
(2019) Sci Immunol 4:
MeSH Terms: Animals, Antineoplastic Agents, Immunological, CD8-Positive T-Lymphocytes, Cell Line, Tumor, Glucose, Glucose Transporter Type 1, Glycolysis, Hepatitis A Virus Cellular Receptor 2, Humans, Immunoglobulin G, Immunotherapy, Adoptive, Lymphocytes, Tumor-Infiltrating, Melanoma, Mice, Inbred C57BL, Phosphopyruvate Hydratase, Programmed Cell Death 1 Receptor
Added March 30, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Loss of CXCR4 in Myeloid Cells Enhances Antitumor Immunity and Reduces Melanoma Growth through NK Cell and FASL Mechanisms.
Yang J, Kumar A, Vilgelm AE, Chen SC, Ayers GD, Novitskiy SV, Joyce S, Richmond A
(2018) Cancer Immunol Res 6: 1186-1198
MeSH Terms: Animals, Bone Marrow Transplantation, Cell Line, Tumor, Cytotoxicity, Immunologic, Fas Ligand Protein, Interleukin-18, Killer Cells, Natural, Macrophages, Melanoma, Experimental, Mice, Inbred C57BL, Mice, Transgenic, Neutrophils, Receptors, CXCR4
Added December 20, 2018
0 Communities
2 Members
0 Resources
13 MeSH Terms
Continued Poor Survival in Metastatic Uveal Melanoma: Implications for Molecular Prognostication, Surveillance Imaging, Adjuvant Therapy, and Clinical Trials.
Johnson DB, Daniels AB
(2018) JAMA Ophthalmol 136: 986-988
MeSH Terms: Combined Modality Therapy, Humans, Melanoma, Survival Rate, Uveal Neoplasms
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms