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Results: 1 to 10 of 300

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Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy.
Barone SM, Paul AG, Muehling LM, Lannigan JA, Kwok WW, Turner RB, Woodfolk JA, Irish JM
(2021) Elife 10:
MeSH Terms: Adolescent, Adult, Algorithms, CD4-Positive T-Lymphocytes, COVID-19, Humans, Leukemia, Myeloid, Acute, Melanoma, Neoplasms, Picornaviridae Infections, Rhinovirus, SARS-CoV-2, Unsupervised Machine Learning, Young Adult
Added August 31, 2021
3 Communities
1 Members
0 Resources
MeSH Terms
Diagnosis of melanoma by imaging mass spectrometry: Development and validation of a melanoma prediction model.
Al-Rohil RN, Moore JL, Patterson NH, Nicholson S, Verbeeck N, Claesen M, Muhammad JZ, Caprioli RM, Norris JL, Kantrow S, Compton M, Robbins J, Alomari AK
(2021) J Cutan Pathol 48: 1455-1462
MeSH Terms: Humans, Melanoma, Sensitivity and Specificity, Skin Neoplasms, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Added November 20, 2021
0 Communities
1 Members
0 Resources
5 MeSH Terms
Impact of body composition on outcomes from anti-PD1 +/- anti-CTLA-4 treatment in melanoma.
Young AC, Quach HT, Song H, Davis EJ, Moslehi JJ, Ye F, Williams GR, Johnson DB
(2020) J Immunother Cancer 8:
MeSH Terms: Body Composition, CTLA-4 Antigen, Female, Humans, Immunotherapy, Male, Melanoma, Middle Aged, Progression-Free Survival, Treatment Outcome
Added September 29, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
Evolving insights into the mechanisms of toxicity associated with immune checkpoint inhibitor therapy.
Mangan BL, McAlister RK, Balko JM, Johnson DB, Moslehi JJ, Gibson A, Phillips EJ
(2020) Br J Clin Pharmacol 86: 1778-1789
MeSH Terms: Drug-Related Side Effects and Adverse Reactions, Humans, Immune Checkpoint Inhibitors, Incidence, Melanoma, Neoplasms, Programmed Cell Death 1 Receptor
Added September 29, 2020
0 Communities
1 Members
0 Resources
7 MeSH Terms
Demographic Factors Associated with Toxicity in Patients Treated with Anti-Programmed Cell Death-1 Therapy.
Shah KP, Song H, Ye F, Moslehi JJ, Balko JM, Salem JE, Johnson DB
(2020) Cancer Immunol Res 8: 851-855
MeSH Terms: Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Antineoplastic Agents, Immunological, CTLA-4 Antigen, Female, Hospitalization, Humans, Immunologic Factors, Immunotherapy, Length of Stay, Male, Melanoma, Middle Aged, Programmed Cell Death 1 Receptor, Risk Factors, Young Adult
Added May 29, 2020
0 Communities
1 Members
0 Resources
19 MeSH Terms
Metastatic Melanoma Patient-Derived Xenografts Respond to MDM2 Inhibition as a Single Agent or in Combination with BRAF/MEK Inhibition.
Shattuck-Brandt RL, Chen SC, Murray E, Johnson CA, Crandall H, O'Neal JF, Al-Rohil RN, Nebhan CA, Bharti V, Dahlman KB, Ayers GD, Yan C, Kelley MC, Kauffmann RM, Hooks M, Grau A, Johnson DB, Vilgelm AE, Richmond A
(2020) Clin Cancer Res 26: 3803-3818
MeSH Terms: Adult, Aged, Animals, Antineoplastic Combined Chemotherapy Protocols, Cell Line, Tumor, Female, Humans, MAP Kinase Signaling System, Male, Melanoma, Mice, Middle Aged, Mitogen-Activated Protein Kinase Kinases, Mutation, Protein Kinase Inhibitors, Proteolysis, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins c-mdm2, Skin Neoplasms, Tumor Suppressor Protein p53, Ubiquitination, Xenograft Model Antitumor Assays
Added May 4, 2020
0 Communities
1 Members
0 Resources
22 MeSH Terms
Multimodal Multiplexed Immunoimaging with Nanostars to Detect Multiple Immunomarkers and Monitor Response to Immunotherapies.
Ou YC, Wen X, Johnson CA, Shae D, Ayala OD, Webb JA, Lin EC, DeLapp RC, Boyd KL, Richmond A, Mahadevan-Jansen A, Rafat M, Wilson JT, Balko JM, Tantawy MN, Vilgelm AE, Bardhan R
(2020) ACS Nano 14: 651-663
MeSH Terms: Animals, B7-H1 Antigen, Biomarkers, Tumor, Cell Line, Tumor, Disease Models, Animal, Gold, Immunotherapy, Melanoma, Metal Nanoparticles, Mice, Optical Imaging, Particle Size, Surface Properties, Tumor Necrosis Factor Receptor Superfamily, Member 9
Added March 17, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21.
Vilgelm AE, Saleh N, Shattuck-Brandt R, Riemenschneider K, Slesur L, Chen SC, Johnson CA, Yang J, Blevins A, Yan C, Johnson DB, Al-Rohil RN, Halilovic E, Kauffmann RM, Kelley M, Ayers GD, Richmond A
(2019) Sci Transl Med 11:
MeSH Terms: Analysis of Variance, Animals, Blotting, Western, Cell Cycle, Cell Survival, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, Cyclin-Dependent Kinase Inhibitor p21, DNA Replication, Dimethyl Sulfoxide, Humans, Immunoprecipitation, MCF-7 Cells, Melanoma, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Nude, Proteomics, Proto-Oncogene Proteins c-mdm2, Radioimmunoprecipitation Assay
Added September 27, 2019
0 Communities
1 Members
0 Resources
21 MeSH Terms
Identification of Targetable Recurrent MAP3K8 Rearrangements in Melanomas Lacking Known Driver Mutations.
Lehmann BD, Shaver TM, Johnson DB, Li Z, Gonzalez-Ericsson PI, Sánchez V, Shyr Y, Sanders ME, Pietenpol JA
(2019) Mol Cancer Res 17: 1842-1853
MeSH Terms: Algorithms, Cell Line, Tumor, Databases, Genetic, Female, Gene Amplification, Gene Expression Regulation, Neoplastic, Humans, MAP Kinase Kinase Kinases, Male, Melanoma, Protein Kinase Inhibitors, Proto-Oncogene Proteins, Sequence Analysis, RNA, Sequence Deletion, Survival Analysis, Translocation, Genetic, Up-Regulation
Added March 30, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
Quantifying Drug Combination Synergy along Potency and Efficacy Axes.
Meyer CT, Wooten DJ, Paudel BB, Bauer J, Hardeman KN, Westover D, Lovly CM, Harris LA, Tyson DR, Quaranta V
(2019) Cell Syst 8: 97-108.e16
MeSH Terms: Drug Combinations, Drug Synergism, Humans, Melanoma
Added March 23, 2019
0 Communities
3 Members
0 Resources
4 MeSH Terms