Metformin Improves Learning and Memory in the SAMP8 Mouse Model of Alzheimer's Disease.
Farr SA, Roesler E, Niehoff ML, Roby DA, McKee A, Morley JE
(2019) J Alzheimers Dis 68
: 1699-1710MeSH Terms: Alzheimer Disease, Animals, Disease Models, Animal, Maze Learning, Memory, Metformin, Mice, Neuroprotective Agents, Treatment OutcomeAdded April 30, 2019
9 MeSH Terms
Inhibition of Glycogen Synthase Kinase 3β as a Treatment for the Prevention of Cognitive Deficits after a Traumatic Brain Injury.
Farr SA, Niehoff ML, Kumar VB, Roby DA, Morley JE
(2019) J Neurotrauma 36
: 1869-1875MeSH Terms: Animals, Brain Injuries, Traumatic, Cognitive Dysfunction, Glycogen Synthase Kinase 3 beta, Maze Learning, Mice, Oligonucleotides, AntisenseAdded March 12, 2019
7 MeSH Terms
HCN channels in the hippocampus regulate active coping behavior.
Fisher DW, Han Y, Lyman KA, Heuermann RJ, Bean LA, Ybarra N, Foote KM, Dong H, Nicholson DA, Chetkovich DM
(2018) J Neurochem 146
: 753-766MeSH Terms: Adaptation, Psychological, Animals, Avoidance Learning, Depression, Disease Models, Animal, Exploratory Behavior, Hippocampus, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Male, Maze Learning, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Transgenic, Microscopy, Electron, Peroxins, Pyramidal Cells, SwimmingAdded April 2, 2019
18 MeSH Terms
Therapeutic endocannabinoid augmentation for mood and anxiety disorders: comparative profiling of FAAH, MAGL and dual inhibitors.
Bedse G, Bluett RJ, Patrick TA, Romness NK, Gaulden AD, Kingsley PJ, Plath N, Marnett LJ, Patel S
(2018) Transl Psychiatry 8
: 92MeSH Terms: Amidohydrolases, Animals, Anti-Anxiety Agents, Anxiety Disorders, Behavior, Animal, Benzodioxoles, Body Temperature, Brain, Carbamates, Endocannabinoids, Female, Locomotion, Male, Maze Learning, Mice, Inbred C57BL, Mice, Inbred ICR, Monoacylglycerol Lipases, Piperazines, Piperidines, Pyridines, Stress, PsychologicalAdded April 12, 2019
OCD candidate gene /EAAT3 impacts basal ganglia-mediated activity and stereotypic behavior.
Zike ID, Chohan MO, Kopelman JM, Krasnow EN, Flicker D, Nautiyal KM, Bubser M, Kellendonk C, Jones CK, Stanwood G, Tanaka KF, Moore H, Ahmari SE, Veenstra-VanderWeele J
(2017) Proc Natl Acad Sci U S A 114
: 5719-5724MeSH Terms: Amphetamines, Animals, Basal Ganglia, Cell Line, Central Nervous System Stimulants, Dopamine, Excitatory Amino Acid Transporter 3, Glutamic Acid, Grooming, Maze Learning, Mice, Mice, Inbred C57BL, Mice, Transgenic, Motor Activity, Obsessive-Compulsive Disorder, Receptors, Dopamine D1, Reflex, StartleAdded March 18, 2020
Aerosol Delivery of Curcumin Reduced Amyloid-β Deposition and Improved Cognitive Performance in a Transgenic Model of Alzheimer's Disease.
McClure R, Ong H, Janve V, Barton S, Zhu M, Li B, Dawes M, Jerome WG, Anderson A, Massion P, Gore JC, Pham W
(2017) J Alzheimers Dis 55
: 797-811MeSH Terms: Administration, Inhalation, Alzheimer Disease, Amyloid beta-Peptides, Amyloid beta-Protein Precursor, Analysis of Variance, Animals, Anti-Inflammatory Agents, Non-Steroidal, Cognition Disorders, Curcumin, Dendritic Spines, Disease Models, Animal, Hippocampus, Humans, Maze Learning, Memory, Short-Term, Mice, Mice, Inbred C57BL, Mice, Transgenic, Microscopy, Electron, Transmission, Mutation, Neurons, Presenilin-1Added April 10, 2017
22 MeSH Terms
Competition between the Brain and Testes under Selenium-Compromised Conditions: Insight into Sex Differences in Selenium Metabolism and Risk of Neurodevelopmental Disease.
Pitts MW, Kremer PM, Hashimoto AC, Torres DJ, Byrns CN, Williams CS, Berry MJ
(2015) J Neurosci 35
: 15326-38MeSH Terms: Age Factors, Animals, Brain, Castration, Dizocilpine Maleate, Epilepsy, Reflex, Exploratory Behavior, Female, Gene Expression Regulation, Glutamate Decarboxylase, Lyases, Male, Maze Learning, Mice, Mice, Inbred C57BL, Mice, Transgenic, Motor Activity, Nerve Tissue Proteins, Neurodevelopmental Disorders, Selenium, Selenoprotein P, Sex Factors, Transcription FactorsAdded March 29, 2016
23 MeSH Terms
IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging.
Toth P, Tarantini S, Ashpole NM, Tucsek Z, Milne GL, Valcarcel-Ares NM, Menyhart A, Farkas E, Sonntag WE, Csiszar A, Ungvari Z
(2015) Aging Cell 14
: 1034-44MeSH Terms: Aging, Animals, Brain, Cerebrovascular Circulation, Cognition Disorders, Disease Models, Animal, Insulin-Like Growth Factor I, Male, Maze Learning, Mice, Mice, Inbred C57BL, Mice, Knockout, Microvessels, Neurovascular Coupling, Nitric Oxide, Spatial MemoryAdded March 10, 2016
16 MeSH Terms
Effects of VU0410120, a novel GlyT1 inhibitor, on measures of sociability, cognition and stereotypic behaviors in a mouse model of autism.
Burket JA, Benson AD, Green TL, Rook JM, Lindsley CW, Conn PJ, Deutsch SI
(2015) Prog Neuropsychopharmacol Biol Psychiatry 61
: 10-7MeSH Terms: Analysis of Variance, Animals, Benzamides, Dose-Response Relationship, Drug, Glycine Plasma Membrane Transport Proteins, Male, Maze Learning, Memory, Short-Term, Mice, Mice, Inbred BALB C, Mice, Inbred ICR, Piperidines, Social Behavior, Spatial Learning, Stereotyped BehaviorAdded February 18, 2016
15 MeSH Terms
Relationship between in vivo receptor occupancy and efficacy of metabotropic glutamate receptor subtype 5 allosteric modulators with different in vitro binding profiles.
Rook JM, Tantawy MN, Ansari MS, Felts AS, Stauffer SR, Emmitte KA, Kessler RM, Niswender CM, Daniels JS, Jones CK, Lindsley CW, Conn PJ
(2015) Neuropsychopharmacology 40
: 755-65MeSH Terms: Allosteric Regulation, Amphetamine, Animals, Benzamides, Calcium, Cerebellum, Corpus Striatum, Dose-Response Relationship, Drug, HEK293 Cells, Humans, Locomotion, Male, Maze Learning, Niacinamide, Piperidines, Positron-Emission Tomography, Radioligand Assay, Rats, Receptor, Metabotropic Glutamate 5, Structure-Activity Relationship, ThiazolesAdded February 19, 2015
21 MeSH Terms