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Results: 1 to 7 of 7

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Unexpected effect of matrix metalloproteinase down-regulation on vascular intravasation and metastasis of human fibrosarcoma cells selected in vivo for high rates of dissemination.
Deryugina EI, Zijlstra A, Partridge JJ, Kupriyanova TA, Madsen MA, Papagiannakopoulos T, Quigley JP
(2005) Cancer Res 65: 10959-69
MeSH Terms: Animals, Antibodies, Monoclonal, Cell Line, Tumor, Chick Embryo, Chorioallantoic Membrane, Down-Regulation, Fibrosarcoma, Humans, Immunohistochemistry, Lung Neoplasms, Matrix Metalloproteinase 9, Matrix Metalloproteinase Inhibitors, Matrix Metalloproteinases, Matrix Metalloproteinases, Membrane-Associated, Neovascularization, Pathologic, RNA, Small Interfering
Added December 30, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain.
Koshikawa N, Minegishi T, Sharabi A, Quaranta V, Seiki M
(2005) J Biol Chem 280: 88-93
MeSH Terms: Animals, Binding Sites, Cell Line, Tumor, Cell Movement, ErbB Receptors, Humans, Laminin, Matrix Metalloproteinases, Membrane-Associated, Metalloendopeptidases, Neoplasm Invasiveness, Rats, Recombinant Proteins, Substrate Specificity
Added February 18, 2013
2 Communities
1 Members
0 Resources
13 MeSH Terms
Proteolytic processing of laminin-5 by MT1-MMP in tissues and its effects on epithelial cell morphology.
Koshikawa N, Schenk S, Moeckel G, Sharabi A, Miyazaki K, Gardner H, Zent R, Quaranta V
(2004) FASEB J 18: 364-6
MeSH Terms: Animals, Cell Adhesion Molecules, Cell Line, Cell Movement, Cell Size, Epithelial Cells, Kidney, Matrix Metalloproteinase 14, Matrix Metalloproteinases, Membrane-Associated, Metalloendopeptidases, Mice, Mice, Knockout, Protein Processing, Post-Translational, Protein Subunits, Rats
Added December 10, 2013
2 Communities
2 Members
0 Resources
15 MeSH Terms
Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma.
Seftor RE, Seftor EA, Koshikawa N, Meltzer PS, Gardner LM, Bilban M, Stetler-Stevenson WG, Quaranta V, Hendrix MJ
(2001) Cancer Res 61: 6322-7
MeSH Terms: Cell Adhesion Molecules, Humans, Matrix Metalloproteinase 2, Matrix Metalloproteinases, Membrane-Associated, Melanoma, Metalloendopeptidases, Molecular Mimicry, Neovascularization, Pathologic, Oligonucleotide Array Sequence Analysis, Oligonucleotides, Antisense, Skin Neoplasms, Tumor Cells, Cultured, Uveal Neoplasms
Added March 27, 2014
1 Communities
1 Members
0 Resources
13 MeSH Terms
Human hepatocellular carcinoma (HCC) cells require both alpha3beta1 integrin and matrix metalloproteinases activity for migration and invasion.
Giannelli G, Bergamini C, Fransvea E, Marinosci F, Quaranta V, Antonaci S
(2001) Lab Invest 81: 613-27
MeSH Terms: Basement Membrane, Carcinoma, Hepatocellular, Cell Adhesion, Cell Adhesion Molecules, Cell Movement, Collagen, Drug Combinations, Extracellular Matrix, Extracellular Matrix Proteins, Humans, Integrin alpha3beta1, Integrins, Laminin, Matrix Metalloproteinase 2, Matrix Metalloproteinases, Matrix Metalloproteinases, Membrane-Associated, Metalloendopeptidases, Neoplasm Invasiveness, Proteoglycans, Tissue Inhibitor of Metalloproteinase-2, Tumor Cells, Cultured
Added March 27, 2014
1 Communities
1 Members
0 Resources
21 MeSH Terms
Cell migration through extracellular matrix: membrane-type metalloproteinases make the way.
Quaranta V
(2000) J Cell Biol 149: 1167-70
MeSH Terms: Animals, Cell Movement, Extracellular Matrix, Humans, Matrix Metalloproteinases, Membrane-Associated, Membrane Proteins, Metalloendopeptidases, Mice, Mice, Knockout, Morphogenesis, Substrate Specificity
Added March 27, 2014
1 Communities
1 Members
0 Resources
11 MeSH Terms
Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5.
Koshikawa N, Giannelli G, Cirulli V, Miyazaki K, Quaranta V
(2000) J Cell Biol 148: 615-24
MeSH Terms: Animals, Cell Adhesion Molecules, Cell Line, Cell Membrane, Cell Movement, Epithelial Cells, HT29 Cells, Humans, Matrix Metalloproteinase 2, Matrix Metalloproteinases, Membrane-Associated, Metalloendopeptidases, Rats, Tumor Cells, Cultured
Added March 27, 2014
1 Communities
1 Members
0 Resources
13 MeSH Terms