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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 33

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Proteolytic cleavage and loss of function of biologic agents that neutralize tumor necrosis factor in the mucosa of patients with inflammatory bowel disease.
Biancheri P, Brezski RJ, Di Sabatino A, Greenplate AR, Soring KL, Corazza GR, Kok KB, Rovedatti L, Vossenkämper A, Ahmad N, Snoek SA, Vermeire S, Rutgeerts P, Jordan RE, MacDonald TT
(2015) Gastroenterology 149: 1564-1574.e3
MeSH Terms: Adalimumab, Antibodies, Monoclonal, Humanized, Biological Factors, Biopsy, Case-Control Studies, Colitis, Ulcerative, Colon, Crohn Disease, Epitopes, Etanercept, Female, Humans, Immunoblotting, Immunoglobulin G, Inflammatory Bowel Diseases, Infliximab, Intestinal Mucosa, Male, Matrix Metalloproteinase 12, Matrix Metalloproteinase 3, Middle Aged, Proteolysis, Tumor Necrosis Factor-alpha
Added April 22, 2016
0 Communities
1 Members
0 Resources
23 MeSH Terms
A monoclonal antibody against hinge-cleaved IgG restores effector function to proteolytically-inactivated IgGs in vitro and in vivo.
Brezski RJ, Kinder M, Grugan KD, Soring KL, Carton J, Greenplate AR, Petley T, Capaldi D, Brosnan K, Emmell E, Watson S, Jordan RE
(2014) MAbs 6: 1265-73
MeSH Terms: Animals, Antibodies, Monoclonal, Antibodies, Monoclonal, Murine-Derived, Antibody-Dependent Cell Cytotoxicity, Bacterial Proteins, Blood Platelets, Cell Line, Cell Line, Tumor, Cysteine Endopeptidases, Dogs, Enzyme-Linked Immunosorbent Assay, Epitopes, Humans, Immunoglobulin Fab Fragments, Immunoglobulin G, Matrix Metalloproteinase 3, Platelet Count, Proteolysis, Rats, Rituximab
Added April 22, 2016
0 Communities
1 Members
0 Resources
20 MeSH Terms
Bone Morphogenetic Proteins stimulate mammary fibroblasts to promote mammary carcinoma cell invasion.
Owens P, Polikowsky H, Pickup MW, Gorska AE, Jovanovic B, Shaw AK, Novitskiy SV, Hong CC, Moses HL
(2013) PLoS One 8: e67533
MeSH Terms: Animals, Bone Morphogenetic Protein 4, Bone Morphogenetic Proteins, Cell Line, Cell Line, Tumor, Female, Fibroblasts, Humans, Interleukin-6, Male, Mammary Neoplasms, Animal, Matrix Metalloproteinase 3, Mice, Neoplasm Invasiveness, Prostatic Neoplasms, Signal Transduction, Up-Regulation
Added February 17, 2014
2 Communities
4 Members
0 Resources
17 MeSH Terms
Simvastatin decreases invasiveness of human endometrial stromal cells.
Sokalska A, Cress A, Bruner-Tran KL, Osteen KG, Taylor HS, Ortega I, Duleba AJ
(2012) Biol Reprod 87: 2, 1-6
MeSH Terms: Animals, Cell Adhesion, Endometriosis, Endometrium, Female, Gene Expression, Humans, Hyaluronan Receptors, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Matrix Metalloproteinase 2, Matrix Metalloproteinase 3, Mice, Mice, Nude, Polyisoprenyl Phosphates, Prenylation, Sesquiterpenes, Simvastatin, Stromal Cells, Tissue Inhibitor of Metalloproteinase-2
Added May 29, 2014
0 Communities
2 Members
0 Resources
19 MeSH Terms
No association between matrix metalloproteinase (MMP)-1, MMP-3, and MMP-7 SNPs and endometrial cancer risk.
Beeghly-Fadiel A, Xiang YB, Deming SL, Long JR, Xu WH, Cai Q, Zheng W, Shu XO
(2009) Cancer Epidemiol Biomarkers Prev 18: 1925-8
MeSH Terms: Adenocarcinoma, Adult, Aged, Endometrial Neoplasms, Female, Genetic Predisposition to Disease, Humans, Matrix Metalloproteinase 1, Matrix Metalloproteinase 3, Matrix Metalloproteinase 7, Middle Aged, Polymorphism, Single Nucleotide, Risk Factors
Added December 10, 2013
0 Communities
3 Members
0 Resources
13 MeSH Terms
Simvastatin protects against the development of endometriosis in a nude mouse model.
Bruner-Tran KL, Osteen KG, Duleba AJ
(2009) J Clin Endocrinol Metab 94: 2489-94
MeSH Terms: Adolescent, Adult, Animals, Anticholesteremic Agents, Cells, Cultured, Disease Models, Animal, Drug Evaluation, Preclinical, Endometriosis, Estradiol, Female, Humans, Matrix Metalloproteinase 3, Mice, Mice, Nude, Middle Aged, Simvastatin, Time Factors, Transplantation, Heterologous, Uterine Diseases, Young Adult
Added May 29, 2014
0 Communities
2 Members
0 Resources
20 MeSH Terms
No association between matrix metalloproteinase-1 or matrix metalloproteinase-3 polymorphisms and breast cancer susceptibility: a report from the Shanghai Breast Cancer Study.
Beeghly-Fadiel A, Cai Q, Lu W, Long J, Gao YT, Shu XO, Zheng W
(2009) Cancer Epidemiol Biomarkers Prev 18: 1324-7
MeSH Terms: Breast Neoplasms, Case-Control Studies, China, Female, Genetic Predisposition to Disease, Genotype, Haplotypes, Humans, Matrix Metalloproteinase 1, Matrix Metalloproteinase 3, Polymorphism, Single Nucleotide, Prognosis
Added March 10, 2014
0 Communities
3 Members
0 Resources
12 MeSH Terms
Keratinocyte expression of MMP3 enhances differentiation and prevents tumor establishment.
McCawley LJ, Wright J, LaFleur BJ, Crawford HC, Matrisian LM
(2008) Am J Pathol 173: 1528-39
MeSH Terms: Animals, Carcinoma, Squamous Cell, Cattle, Cell Differentiation, Cell Line, Tumor, Cell Movement, Cell Proliferation, Cell Survival, Disease Models, Animal, Epidermis, Female, Gene Targeting, Keratin-5, Keratinocytes, Male, Matrix Metalloproteinase 3, Mice, Mice, Transgenic, Neutrophils, Rats, Stromal Cells, Transplantation, Homologous
Added July 10, 2013
0 Communities
2 Members
0 Resources
22 MeSH Terms
Activation of Matrix Metalloproteinase-3 is altered at the frog neuromuscular junction following changes in synaptic activity.
VanSaun M, Humburg BC, Arnett MG, Pence M, Werle MJ
(2007) Dev Neurobiol 67: 1488-97
MeSH Terms: Animals, Enzyme Activation, Extracellular Matrix, Fluorescent Dyes, Matrix Metalloproteinase 3, Neuromuscular Junction, Neuronal Plasticity, Rana pipiens, Schwann Cells, Sodium Channel Blockers, Staining and Labeling, Synaptic Transmission, Tetrodotoxin
Added May 13, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Down-regulation of endometrial matrix metalloproteinase-3 and -7 expression in vitro and therapeutic regression of experimental endometriosis in vivo by a novel nonsteroidal progesterone receptor agonist, tanaproget.
Bruner-Tran KL, Zhang Z, Eisenberg E, Winneker RC, Osteen KG
(2006) J Clin Endocrinol Metab 91: 1554-60
MeSH Terms: Adolescent, Adult, Benzoxazines, Blotting, Western, Cells, Cultured, Down-Regulation, Endometriosis, Endometrium, Female, Humans, Matrix Metalloproteinase 3, Matrix Metalloproteinase 7, Middle Aged, Organ Culture Techniques, Receptors, Progesterone, Stromal Cells, Thiones
Added May 29, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms