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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 48

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Neuronal activity drives FMRP- and HSPG-dependent matrix metalloproteinase function required for rapid synaptogenesis.
Dear ML, Shilts J, Broadie K
(2017) Sci Signal 10:
MeSH Terms: Animals, Disease Models, Animal, Drosophila Proteins, Drosophila melanogaster, Fragile X Syndrome, Heparan Sulfate Proteoglycans, Matrix Metalloproteinase 1, Matrix Metalloproteinase 2, Neuromuscular Junction, Neurons, Presynaptic Terminals, Proteoglycans, Wnt Signaling Pathway
Added December 7, 2017
1 Communities
0 Members
0 Resources
13 MeSH Terms
Both Drosophila matrix metalloproteinases have released and membrane-tethered forms but have different substrates.
LaFever KS, Wang X, Page-McCaw P, Bhave G, Page-McCaw A
(2017) Sci Rep 7: 44560
MeSH Terms: Animals, Cell Adhesion, Cell Membrane, Drosophila melanogaster, Extracellular Matrix, Matrix Metalloproteinase 1, Matrix Metalloproteinase 2, Signal Transduction, Substrate Specificity
Added May 3, 2017
1 Communities
2 Members
0 Resources
9 MeSH Terms
Two classes of matrix metalloproteinases reciprocally regulate synaptogenesis.
Dear ML, Dani N, Parkinson W, Zhou S, Broadie K
(2016) Development 143: 75-87
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Cell Communication, Drosophila, Drosophila Proteins, Frizzled Receptors, Heparan Sulfate Proteoglycans, Matrix Metalloproteinase 1, Matrix Metalloproteinase 2, Neurogenesis, Neuromuscular Junction, Nuclear Proteins, Synapses, Tissue Inhibitor of Metalloproteinases, Wnt Signaling Pathway, Wnt1 Protein
Added March 29, 2017
1 Communities
1 Members
0 Resources
16 MeSH Terms
Stromal matrix metalloproteinase 2 regulates collagen expression and promotes the outgrowth of experimental metastases.
Bates AL, Pickup MW, Hallett MA, Dozier EA, Thomas S, Fingleton B
(2015) J Pathol 235: 773-83
MeSH Terms: Actins, Animals, Cell Proliferation, Coculture Techniques, Collagen, Female, Fibroblasts, Gene Expression Profiling, Humans, Lung Neoplasms, Mammary Neoplasms, Experimental, Matrix Metalloproteinase 2, Mice, Inbred C57BL, Mice, Knockout, Spheroids, Cellular, Stromal Cells, Time Factors, Transfection, Transforming Growth Factor beta1, Vimentin
Added January 20, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.
Wang X, Page-McCaw A
(2014) J Cell Biol 206: 923-36
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Cell Communication, Cell Line, Cell Proliferation, Drosophila Proteins, Drosophila melanogaster, Female, Male, Matrix Metalloproteinase 2, Nuclear Proteins, Ovarian Follicle, Protein Transport, Proteolysis, Stem Cell Niche, Stem Cells, Wnt Signaling Pathway, Wnt1 Protein
Added January 20, 2015
1 Communities
1 Members
0 Resources
18 MeSH Terms
Cannabinoid CB2 receptors regulate central sensitization and pain responses associated with osteoarthritis of the knee joint.
Burston JJ, Sagar DR, Shao P, Bai M, King E, Brailsford L, Turner JM, Hathway GJ, Bennett AJ, Walsh DA, Kendall DA, Lichtman A, Chapman V
(2013) PLoS One 8: e80440
MeSH Terms: Animals, Cannabinoids, Electrophysiology, Enzyme-Linked Immunosorbent Assay, Humans, Matrix Metalloproteinase 2, Matrix Metalloproteinase 9, Osteoarthritis, Knee, Pain, Rats, Rats, Sprague-Dawley, Receptor, Cannabinoid, CB2, Spinal Cord
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells.
Halder SK, Osteen KG, Al-Hendy A
(2013) Hum Reprod 28: 2407-16
MeSH Terms: Antineoplastic Agents, Calcitriol, Cell Line, Tumor, Enzyme Precursors, Female, Gene Expression Regulation, Neoplastic, Humans, Leiomyoma, Matrix Metalloproteinase 2, Matrix Metalloproteinase 9, Myometrium, Neoplasm Proteins, Osmolar Concentration, RNA, Messenger, Receptors, Calcitriol, Tissue Inhibitor of Metalloproteinase-1, Tissue Inhibitor of Metalloproteinase-2, Tumor Cells, Cultured, Uterine Neoplasms
Added May 29, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Systems-level analysis of proteolytic events in increased vascular permeability and complement activation in skin inflammation.
auf dem Keller U, Prudova A, Eckhard U, Fingleton B, Overall CM
(2013) Sci Signal 6: rs2
MeSH Terms: Acetylation, Amino Acid Sequence, Animals, Blood Proteins, Blotting, Western, Bradykinin, Capillary Permeability, Complement Activation, Complement C1 Inhibitor Protein, Complement System Proteins, Dermatitis, Isotope Labeling, Mass Spectrometry, Matrix Metalloproteinase 2, Mice, Mice, Knockout, Molecular Sequence Data, Proteolysis, Proteome, Proteomics, Signal Transduction, Skin, Tetradecanoylphorbol Acetate
Added March 27, 2014
1 Communities
1 Members
0 Resources
23 MeSH Terms
Regulation of CXCR4-mediated invasion by DARPP-32 in gastric cancer cells.
Zhu S, Hong J, Tripathi MK, Sehdev V, Belkhiri A, El-Rifai W
(2013) Mol Cancer Res 11: 86-94
MeSH Terms: Cell Line, Tumor, Dopamine and cAMP-Regulated Phosphoprotein 32, HEK293 Cells, Humans, Matrix Metalloproteinase 14, Matrix Metalloproteinase 2, Neoplasm Invasiveness, Receptors, CXCR4, Signal Transduction, Stomach Neoplasms
Added September 3, 2013
0 Communities
3 Members
0 Resources
10 MeSH Terms
Simvastatin decreases invasiveness of human endometrial stromal cells.
Sokalska A, Cress A, Bruner-Tran KL, Osteen KG, Taylor HS, Ortega I, Duleba AJ
(2012) Biol Reprod 87: 2, 1-6
MeSH Terms: Animals, Cell Adhesion, Endometriosis, Endometrium, Female, Gene Expression, Humans, Hyaluronan Receptors, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Matrix Metalloproteinase 2, Matrix Metalloproteinase 3, Mice, Mice, Nude, Polyisoprenyl Phosphates, Prenylation, Sesquiterpenes, Simvastatin, Stromal Cells, Tissue Inhibitor of Metalloproteinase-2
Added May 29, 2014
0 Communities
2 Members
0 Resources
19 MeSH Terms