Neuronal activity drives FMRP- and HSPG-dependent matrix metalloproteinase function required for rapid synaptogenesis.
Dear ML, Shilts J, Broadie K
(2017) Sci Signal 10
: MeSH Terms: Animals, Disease Models, Animal, Drosophila Proteins, Drosophila melanogaster, Fragile X Syndrome, Heparan Sulfate Proteoglycans, Matrix Metalloproteinase 1, Matrix Metalloproteinase 2, Neuromuscular Junction, Neurons, Presynaptic Terminals, Proteoglycans, Wnt Signaling PathwayAdded December 7, 2017
13 MeSH Terms
Both Drosophila matrix metalloproteinases have released and membrane-tethered forms but have different substrates.
LaFever KS, Wang X, Page-McCaw P, Bhave G, Page-McCaw A
(2017) Sci Rep 7
: 44560MeSH Terms: Animals, Cell Adhesion, Cell Membrane, Drosophila melanogaster, Extracellular Matrix, Matrix Metalloproteinase 1, Matrix Metalloproteinase 2, Signal Transduction, Substrate SpecificityAdded May 3, 2017
9 MeSH Terms
Two classes of matrix metalloproteinases reciprocally regulate synaptogenesis.
Dear ML, Dani N, Parkinson W, Zhou S, Broadie K
(2016) Development 143
: 75-87MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Cell Communication, Drosophila, Drosophila Proteins, Frizzled Receptors, Heparan Sulfate Proteoglycans, Matrix Metalloproteinase 1, Matrix Metalloproteinase 2, Neurogenesis, Neuromuscular Junction, Nuclear Proteins, Synapses, Tissue Inhibitor of Metalloproteinases, Wnt Signaling Pathway, Wnt1 ProteinAdded March 29, 2017
16 MeSH Terms
Stromal matrix metalloproteinase 2 regulates collagen expression and promotes the outgrowth of experimental metastases.
Bates AL, Pickup MW, Hallett MA, Dozier EA, Thomas S, Fingleton B
(2015) J Pathol 235
: 773-83MeSH Terms: Actins, Animals, Cell Proliferation, Coculture Techniques, Collagen, Female, Fibroblasts, Gene Expression Profiling, Humans, Lung Neoplasms, Mammary Neoplasms, Experimental, Matrix Metalloproteinase 2, Mice, Inbred C57BL, Mice, Knockout, Spheroids, Cellular, Stromal Cells, Time Factors, Transfection, Transforming Growth Factor beta1, VimentinAdded January 20, 2015
20 MeSH Terms
A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.
Wang X, Page-McCaw A
(2014) J Cell Biol 206
: 923-36MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Cell Communication, Cell Line, Cell Proliferation, Drosophila Proteins, Drosophila melanogaster, Female, Male, Matrix Metalloproteinase 2, Nuclear Proteins, Ovarian Follicle, Protein Transport, Proteolysis, Stem Cell Niche, Stem Cells, Wnt Signaling Pathway, Wnt1 ProteinAdded January 20, 2015
18 MeSH Terms
Cannabinoid CB2 receptors regulate central sensitization and pain responses associated with osteoarthritis of the knee joint.
Burston JJ, Sagar DR, Shao P, Bai M, King E, Brailsford L, Turner JM, Hathway GJ, Bennett AJ, Walsh DA, Kendall DA, Lichtman A, Chapman V
(2013) PLoS One 8
: e80440MeSH Terms: Animals, Cannabinoids, Electrophysiology, Enzyme-Linked Immunosorbent Assay, Humans, Matrix Metalloproteinase 2, Matrix Metalloproteinase 9, Osteoarthritis, Knee, Pain, Rats, Rats, Sprague-Dawley, Receptor, Cannabinoid, CB2, Spinal CordAdded April 2, 2019
Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells.
Halder SK, Osteen KG, Al-Hendy A
(2013) Hum Reprod 28
: 2407-16MeSH Terms: Antineoplastic Agents, Calcitriol, Cell Line, Tumor, Enzyme Precursors, Female, Gene Expression Regulation, Neoplastic, Humans, Leiomyoma, Matrix Metalloproteinase 2, Matrix Metalloproteinase 9, Myometrium, Neoplasm Proteins, Osmolar Concentration, RNA, Messenger, Receptors, Calcitriol, Tissue Inhibitor of Metalloproteinase-1, Tissue Inhibitor of Metalloproteinase-2, Tumor Cells, Cultured, Uterine NeoplasmsAdded May 29, 2014
19 MeSH Terms
Systems-level analysis of proteolytic events in increased vascular permeability and complement activation in skin inflammation.
auf dem Keller U, Prudova A, Eckhard U, Fingleton B, Overall CM
(2013) Sci Signal 6
: rs2MeSH Terms: Acetylation, Amino Acid Sequence, Animals, Blood Proteins, Blotting, Western, Bradykinin, Capillary Permeability, Complement Activation, Complement C1 Inhibitor Protein, Complement System Proteins, Dermatitis, Isotope Labeling, Mass Spectrometry, Matrix Metalloproteinase 2, Mice, Mice, Knockout, Molecular Sequence Data, Proteolysis, Proteome, Proteomics, Signal Transduction, Skin, Tetradecanoylphorbol AcetateAdded March 27, 2014
23 MeSH Terms
Regulation of CXCR4-mediated invasion by DARPP-32 in gastric cancer cells.
Zhu S, Hong J, Tripathi MK, Sehdev V, Belkhiri A, El-Rifai W
(2013) Mol Cancer Res 11
: 86-94MeSH Terms: Cell Line, Tumor, Dopamine and cAMP-Regulated Phosphoprotein 32, HEK293 Cells, Humans, Matrix Metalloproteinase 14, Matrix Metalloproteinase 2, Neoplasm Invasiveness, Receptors, CXCR4, Signal Transduction, Stomach NeoplasmsAdded September 3, 2013
10 MeSH Terms
Simvastatin decreases invasiveness of human endometrial stromal cells.
Sokalska A, Cress A, Bruner-Tran KL, Osteen KG, Taylor HS, Ortega I, Duleba AJ
(2012) Biol Reprod 87
: 2, 1-6MeSH Terms: Animals, Cell Adhesion, Endometriosis, Endometrium, Female, Gene Expression, Humans, Hyaluronan Receptors, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Matrix Metalloproteinase 2, Matrix Metalloproteinase 3, Mice, Mice, Nude, Polyisoprenyl Phosphates, Prenylation, Sesquiterpenes, Simvastatin, Stromal Cells, Tissue Inhibitor of Metalloproteinase-2Added May 29, 2014
19 MeSH Terms