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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 10

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Alternative splicing of ALCAM enables tunable regulation of cell-cell adhesion through differential proteolysis.
Hebron KE, Li EY, Arnold Egloff SA, von Lersner AK, Taylor C, Houkes J, Flaherty DK, Eskaros A, Stricker TP, Zijlstra A
(2018) Sci Rep 8: 3208
MeSH Terms: Activated-Leukocyte Cell Adhesion Molecule, Alternative Splicing, Animals, Cell Adhesion, Cell Line, Tumor, Chick Embryo, Chorioallantoic Membrane, Disease Progression, Humans, Matrix Metalloproteinase 14, Neoplasm Metastasis, Proteolysis, Urinary Bladder Neoplasms
Added March 22, 2018
0 Communities
2 Members
0 Resources
13 MeSH Terms
Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein.
Koshikawa N, Hoshino D, Taniguchi H, Minegishi T, Tomari T, Nam SO, Aoki M, Sueta T, Nakagawa T, Miyamoto S, Nabeshima K, Weaver AM, Seiki M
(2015) Cancer Res 75: 3327-39
MeSH Terms: Animals, Binding Sites, Blotting, Western, Cell Line, Tumor, Humans, Male, Matrix Metalloproteinase 14, Mice, Inbred BALB C, Microscopy, Fluorescence, Mutation, Neoplasm Metastasis, Neoplasms, Oncogene Proteins, Phosphorylation, Proteolysis, RNA Interference, Receptor, EphA2, Transplantation, Heterologous, Tumor Burden, Tumor Suppressor Proteins
Added February 15, 2016
1 Communities
1 Members
0 Resources
20 MeSH Terms
Regulation of CXCR4-mediated invasion by DARPP-32 in gastric cancer cells.
Zhu S, Hong J, Tripathi MK, Sehdev V, Belkhiri A, El-Rifai W
(2013) Mol Cancer Res 11: 86-94
MeSH Terms: Cell Line, Tumor, Dopamine and cAMP-Regulated Phosphoprotein 32, HEK293 Cells, Humans, Matrix Metalloproteinase 14, Matrix Metalloproteinase 2, Neoplasm Invasiveness, Receptors, CXCR4, Signal Transduction, Stomach Neoplasms
Added September 3, 2013
0 Communities
3 Members
0 Resources
10 MeSH Terms
Establishment and validation of computational model for MT1-MMP dependent ECM degradation and intervention strategies.
Hoshino D, Koshikawa N, Suzuki T, Quaranta V, Weaver AM, Seiki M, Ichikawa K
(2012) PLoS Comput Biol 8: e1002479
MeSH Terms: Animals, Carcinoma, Squamous Cell, Cell Line, Tumor, Cell Membrane, Computer Simulation, Extracellular Matrix, Matrix Metalloproteinase 14, Models, Biological, Signal Transduction
Added February 18, 2013
3 Communities
1 Members
0 Resources
9 MeSH Terms
MT1-MMP-mediated basement membrane remodeling modulates renal development.
Riggins KS, Mernaugh G, Su Y, Quaranta V, Koshikawa N, Seiki M, Pozzi A, Zent R
(2010) Exp Cell Res 316: 2993-3005
MeSH Terms: Animals, Basement Membrane, Cell Movement, Cell Proliferation, Extracellular Matrix, Kidney, Matrix Metalloproteinase 14, Mice, Mice, Knockout, Phenotype
Added February 24, 2014
3 Communities
3 Members
0 Resources
10 MeSH Terms
MT2-MMP-dependent release of collagen IV NC1 domains regulates submandibular gland branching morphogenesis.
Rebustini IT, Myers C, Lassiter KS, Surmak A, Szabova L, Holmbeck K, Pedchenko V, Hudson BG, Hoffman MP
(2009) Dev Cell 17: 482-93
MeSH Terms: Animals, Blotting, Western, Cell Proliferation, Collagen Type IV, Epithelial Cells, Fluorescent Antibody Technique, Heparin, Heparin-binding EGF-like Growth Factor, Immunoprecipitation, Integrin beta1, Intercellular Signaling Peptides and Proteins, Matrix Metalloproteinase 14, Matrix Metalloproteinase 15, Matrix Metalloproteinase Inhibitors, Mice, Mice, Knockout, Morphogenesis, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, RNA, Messenger, RNA, Small Interfering, Reverse Transcriptase Polymerase Chain Reaction, Submandibular Gland
Added December 10, 2013
1 Communities
2 Members
0 Resources
23 MeSH Terms
The planar cell polarity protein Van Gogh-Like 2 regulates tumor cell migration and matrix metalloproteinase-dependent invasion.
Cantrell VA, Jessen JR
(2010) Cancer Lett 287: 54-61
MeSH Terms: Cell Line, Tumor, Cell Movement, Cell Polarity, Humans, Intracellular Signaling Peptides and Proteins, Matrix Metalloproteinase 14, Matrix Metalloproteinase 2, Membrane Proteins, Neoplasm Invasiveness
Added March 7, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
Sun Y, Ishibashi M, Seimon T, Lee M, Sharma SM, Fitzgerald KA, Samokhin AO, Wang Y, Sayers S, Aikawa M, Jerome WG, Ostrowski MC, Bromme D, Libby P, Tabas IA, Welch CL, Tall AR
(2009) Circ Res 104: 455-65
MeSH Terms: Adaptor Proteins, Vesicular Transport, Animals, Aorta, Apolipoproteins E, Calgranulin A, Cathepsin K, Cathepsins, Cell Membrane, Cells, Cultured, Cholesterol, E-Box Elements, Endosomes, Enzyme Induction, Humans, Intracellular Signaling Peptides and Proteins, Macrophages, Matrix Metalloproteinase 14, Matrix Metalloproteinase 8, Mice, Mice, Inbred C3H, Mice, Inbred C57BL, Mice, Knockout, Microphthalmia-Associated Transcription Factor, Niemann-Pick C1 Protein, Phosphorylation, Promoter Regions, Genetic, Proteins, Receptor Activator of Nuclear Factor-kappa B, S100 Proteins, Signal Transduction, Time Factors, Toll-Like Receptor 3, Toll-Like Receptor 4, p38 Mitogen-Activated Protein Kinases, rab GTP-Binding Proteins
Added December 10, 2013
0 Communities
1 Members
0 Resources
35 MeSH Terms
Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia.
Clark ES, Whigham AS, Yarbrough WG, Weaver AM
(2007) Cancer Res 67: 4227-35
MeSH Terms: Actins, Carcinoma, Squamous Cell, Cell Line, Tumor, Cell Membrane, Cortactin, Extracellular Matrix, Head and Neck Neoplasms, Humans, Isoenzymes, Matrix Metalloproteinase 14, Matrix Metalloproteinase Inhibitors, Matrix Metalloproteinases
Added March 5, 2014
1 Communities
1 Members
0 Resources
12 MeSH Terms
Proteolytic processing of laminin-5 by MT1-MMP in tissues and its effects on epithelial cell morphology.
Koshikawa N, Schenk S, Moeckel G, Sharabi A, Miyazaki K, Gardner H, Zent R, Quaranta V
(2004) FASEB J 18: 364-6
MeSH Terms: Animals, Cell Adhesion Molecules, Cell Line, Cell Movement, Cell Size, Epithelial Cells, Kidney, Matrix Metalloproteinase 14, Matrix Metalloproteinases, Membrane-Associated, Metalloendopeptidases, Mice, Mice, Knockout, Protein Processing, Post-Translational, Protein Subunits, Rats
Added December 10, 2013
2 Communities
2 Members
0 Resources
15 MeSH Terms