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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 86

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Identification of a selective manganese ionophore that enables nonlethal quantification of cellular manganese.
Horning KJ, Joshi P, Nitin R, Balachandran RC, Yanko FM, Kim K, Christov P, Aschner M, Sulikowski GA, Weaver CD, Bowman AB
(2020) J Biol Chem 295: 3875-3890
MeSH Terms: Animals, Calcimycin, Calcium, Cell Line, Cell Survival, Fura-2, HEK293 Cells, Humans, Induced Pluripotent Stem Cells, Ionomycin, Ionophores, Male, Manganese, Mass Spectrometry, Mice
Added March 27, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Manganese Detoxification by MntE Is Critical for Resistance to Oxidative Stress and Virulence of .
Grunenwald CM, Choby JE, Juttukonda LJ, Beavers WN, Weiss A, Torres VJ, Skaar EP
(2019) mBio 10:
MeSH Terms: Animals, Cation Transport Proteins, Disease Models, Animal, Gene Expression Regulation, Bacterial, Homeostasis, Iron, Manganese, Mice, Inbred BALB C, Microbial Viability, Oxidative Stress, Staphylococcal Infections, Staphylococcus aureus, Transcription Factors, Transcription, Genetic, Virulence
Added April 2, 2019
0 Communities
1 Members
0 Resources
15 MeSH Terms
S100 Proteins in the Innate Immune Response to Pathogens.
Kozlyuk N, Monteith AJ, Garcia V, Damo SM, Skaar EP, Chazin WJ
(2019) Methods Mol Biol 1929: 275-290
MeSH Terms: Calcium, Host-Pathogen Interactions, Humans, Immunity, Innate, Inflammation, Manganese, Models, Molecular, Protein Conformation, S100 Proteins, Toll-Like Receptor 4
Added March 26, 2019
0 Communities
2 Members
0 Resources
10 MeSH Terms
Antimicrobial action of calprotectin that does not involve metal withholding.
Besold AN, Culbertson EM, Nam L, Hobbs RP, Boyko A, Maxwell CN, Chazin WJ, Marques AR, Culotta VC
(2018) Metallomics 10: 1728-1742
MeSH Terms: Anti-Bacterial Agents, Borrelia burgdorferi, Escherichia coli, Glossitis, Benign Migratory, Humans, Leukocyte L1 Antigen Complex, Lyme Disease, Manganese, Neutrophils, Zinc
Added March 26, 2019
0 Communities
1 Members
0 Resources
10 MeSH Terms
From the Cover: Manganese and Rotenone-Induced Oxidative Stress Signatures Differ in iPSC-Derived Human Dopamine Neurons.
Neely MD, Davison CA, Aschner M, Bowman AB
(2017) Toxicol Sci 159: 366-379
MeSH Terms: Cell Differentiation, Cells, Cultured, Dopaminergic Neurons, Humans, Induced Pluripotent Stem Cells, Lipid Peroxidation, Manganese, Oxidative Stress, Reactive Nitrogen Species, Reactive Oxygen Species, Rotenone
Added April 11, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms
Dietary Manganese Promotes Staphylococcal Infection of the Heart.
Juttukonda LJ, Berends ETM, Zackular JP, Moore JL, Stier MT, Zhang Y, Schmitz JE, Beavers WN, Wijers CD, Gilston BA, Kehl-Fie TE, Atkinson J, Washington MK, Peebles RS, Chazin WJ, Torres VJ, Caprioli RM, Skaar EP
(2017) Cell Host Microbe 22: 531-542.e8
MeSH Terms: Abscess, Animals, Diet, Disease Models, Animal, Endocarditis, Bacterial, Heart, Humans, Leukocyte L1 Antigen Complex, Liver, Manganese, Mice, Mice, Congenic, Mice, Inbred C57BL, Neutrophils, Reactive Oxygen Species, Staphylococcal Infections, Staphylococcus aureus
Added March 14, 2018
0 Communities
4 Members
0 Resources
17 MeSH Terms
Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders.
Bryan MR, Bowman AB
(2017) Adv Neurobiol 18: 113-142
MeSH Terms: Alzheimer Disease, Amyotrophic Lateral Sclerosis, Animals, Autophagy, Brain, Disease Models, Animal, Humans, Huntingtin Protein, Huntington Disease, Insulin, Manganese, Mitochondria, Neostriatum, Neural Stem Cells, Neurodegenerative Diseases, Parkinson Disease, Reactive Oxygen Species, Signal Transduction, Somatomedins
Added April 11, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Phosphatidylinositol 3 kinase (PI3K) modulates manganese homeostasis and manganese-induced cell signaling in a murine striatal cell line.
Bryan MR, Uhouse MA, Nordham KD, Joshi P, Rose DIR, O'Brien MT, Aschner M, Bowman AB
(2018) Neurotoxicology 64: 185-194
MeSH Terms: Animals, Cell Line, Chromones, Corpus Striatum, HEK293 Cells, Homeostasis, Humans, Induced Pluripotent Stem Cells, Inhibitory Concentration 50, Manganese, Mice, Morpholines, Neural Stem Cells, Phosphatidylinositol 3-Kinase, Signal Transduction, Tumor Suppressor Protein p53
Added April 11, 2018
0 Communities
1 Members
0 Resources
16 MeSH Terms
Relationships Between Essential Manganese Biology and Manganese Toxicity in Neurological Disease.
Pfalzer AC, Bowman AB
(2017) Curr Environ Health Rep 4: 223-228
MeSH Terms: Aging, Central Nervous System Diseases, Humans, Manganese, Manganese Poisoning, Neurotoxicity Syndromes, Risk Factors
Added April 26, 2017
0 Communities
1 Members
0 Resources
7 MeSH Terms
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model.
Bichell TJV, Wegrzynowicz M, Tipps KG, Bradley EM, Uhouse MA, Bryan M, Horning K, Fisher N, Dudek K, Halbesma T, Umashanker P, Stubbs AD, Holt HK, Kwakye GF, Tidball AM, Colbran RJ, Aschner M, Neely MD, Di Pardo A, Maglione V, Osmand A, Bowman AB
(2017) Biochim Biophys Acta Mol Basis Dis 1863: 1596-1604
MeSH Terms: Animals, Arginase, Corpus Striatum, Disease Models, Animal, Huntington Disease, Male, Manganese, Mice, Neurons, Urea
Added April 26, 2017
0 Communities
2 Members
0 Resources
10 MeSH Terms