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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 89

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Treatment-Induced Tumor Cell Apoptosis and Secondary Necrosis Drive Tumor Progression in the Residual Tumor Microenvironment through MerTK and IDO1.
Werfel TA, Elion DL, Rahman B, Hicks DJ, Sanchez V, Gonzales-Ericsson PI, Nixon MJ, James JL, Balko JM, Scherle PA, Koblish HK, Cook RS
(2019) Cancer Res 79: 171-182
MeSH Terms: Animals, Antineoplastic Agents, Apoptosis, Female, Indoleamine-Pyrrole 2,3,-Dioxygenase, Inflammation, Lapatinib, Lung Neoplasms, Macrophages, Mammary Neoplasms, Experimental, Mice, Necrosis, Phagocytosis, Receptor, ErbB-2, T-Lymphocytes, Regulatory, Tumor Microenvironment, c-Mer Tyrosine Kinase
Added April 15, 2019
0 Communities
1 Members
0 Resources
17 MeSH Terms
Early TGF-β inhibition in mice reduces the incidence of breast cancer induced bone disease in a myeloid dependent manner.
Buenrostro D, Kwakwa KA, Putnam NE, Merkel AR, Johnson JR, Cassat JE, Sterling JA
(2018) Bone 113: 77-88
MeSH Terms: Animals, Bone Neoplasms, Female, Humans, Mammary Neoplasms, Experimental, Mice, Mice, Knockout, Myeloid Progenitor Cells, Transforming Growth Factor beta, Tumor Microenvironment
Added April 15, 2019
0 Communities
2 Members
0 Resources
10 MeSH Terms
DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer.
Luo N, Nixon MJ, Gonzalez-Ericsson PI, Sanchez V, Opalenik SR, Li H, Zahnow CA, Nickels ML, Liu F, Tantawy MN, Sanders ME, Manning HC, Balko JM
(2018) Nat Commun 9: 248
MeSH Terms: Animals, Antineoplastic Agents, Azacitidine, Breast Neoplasms, Cell Line, Tumor, DNA (Cytosine-5-)-Methyltransferase 1, Female, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Genes, MHC Class I, Humans, Mammary Neoplasms, Experimental, Mice, Promoter Regions, Genetic, T-Lymphocytes, Cytotoxic
Added March 14, 2018
0 Communities
4 Members
0 Resources
15 MeSH Terms
IL-17RC is critically required to maintain baseline A20 production to repress JNK isoform-dependent tumor-specific proliferation.
Yan C, Lei Y, Lin TJ, Hoskin DW, Ma A, Wang J
(2017) Oncotarget 8: 43153-43168
MeSH Terms: Animals, Cell Line, Tumor, Cell Proliferation, Female, Interleukin-17, Isoenzymes, MAP Kinase Kinase 4, Male, Mammary Neoplasms, Experimental, Melanoma, Melanoma, Experimental, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Receptors, Interleukin-17, Signal Transduction, Transcription Factors, Transfection, Tumor Necrosis Factor alpha-Induced Protein 3
Added May 15, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Matrix stiffening promotes a tumor vasculature phenotype.
Bordeleau F, Mason BN, Lollis EM, Mazzola M, Zanotelli MR, Somasegar S, Califano JP, Montague C, LaValley DJ, Huynh J, Mencia-Trinchant N, Negrón Abril YL, Hassane DC, Bonassar LJ, Butcher JT, Weiss RS, Reinhart-King CA
(2017) Proc Natl Acad Sci U S A 114: 492-497
MeSH Terms: Animals, Biomechanical Phenomena, Cattle, Cells, Cultured, Chick Embryo, Collagen, Extracellular Matrix, Female, Human Umbilical Vein Endothelial Cells, Humans, Mammary Neoplasms, Experimental, Matrix Metalloproteinases, Mice, Microvessels, Neoplasm Invasiveness, Neovascularization, Pathologic, Phenotype, Tumor Microenvironment, Vascular Stiffness
Added April 10, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Mouse Models of Breast Cancer: Platforms for Discovering Precision Imaging Diagnostics and Future Cancer Medicine.
Manning HC, Buck JR, Cook RS
(2016) J Nucl Med 57 Suppl 1: 60S-8S
MeSH Terms: Animals, Breast Neoplasms, Disease Models, Animal, Female, Humans, Mammary Neoplasms, Experimental, Mice, Molecular Imaging, Neoplasm Transplantation, Precision Medicine, Radionuclide Imaging
Added February 11, 2016
0 Communities
2 Members
0 Resources
11 MeSH Terms
Small molecule/ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition.
An H, Stoops SL, Deane NG, Zhu J, Zi J, Weaver C, Waterson AG, Zijlstra A, Lindsley CW, Beauchamp RD
(2015) Oncotarget 6: 22934-48
MeSH Terms: Animals, Cadherins, Cell Line, Tumor, Chick Embryo, Colorectal Neoplasms, Epithelial-Mesenchymal Transition, Female, Humans, Isoxazoles, Lung Neoplasms, Mammary Neoplasms, Experimental, Mice, Neoplasm Invasiveness, Neoplasms, Niacinamide, Small Molecule Libraries, Transcription, Genetic
Added July 16, 2015
1 Communities
3 Members
0 Resources
17 MeSH Terms
TGFβ signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions.
Shaw AK, Pickup MW, Chytil A, Aakre M, Owens P, Moses HL, Novitskiy SV
(2015) PLoS One 10: e0117908
MeSH Terms: Animals, Cell Line, Tumor, Cell Movement, Female, Fibroblasts, Mammary Neoplasms, Experimental, Mice, Myeloid Cells, Neoplasm Invasiveness, Protein-Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Transforming Growth Factor beta
Added February 12, 2015
1 Communities
2 Members
0 Resources
14 MeSH Terms
Stromal matrix metalloproteinase 2 regulates collagen expression and promotes the outgrowth of experimental metastases.
Bates AL, Pickup MW, Hallett MA, Dozier EA, Thomas S, Fingleton B
(2015) J Pathol 235: 773-83
MeSH Terms: Actins, Animals, Cell Proliferation, Coculture Techniques, Collagen, Female, Fibroblasts, Gene Expression Profiling, Humans, Lung Neoplasms, Mammary Neoplasms, Experimental, Matrix Metalloproteinase 2, Mice, Inbred C57BL, Mice, Knockout, Spheroids, Cellular, Stromal Cells, Time Factors, Transfection, Transforming Growth Factor beta1, Vimentin
Added January 20, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis.
Novitskiy SV, Forrester E, Pickup MW, Gorska AE, Chytil A, Aakre M, Polosukhina D, Owens P, Yusupova DR, Zhao Z, Ye F, Shyr Y, Moses HL
(2014) Breast Cancer Res 16: 425
MeSH Terms: Animals, Carcinogenesis, Chemokines, Female, Humans, Lung Neoplasms, Mammary Neoplasms, Experimental, Mice, Transgenic, Neovascularization, Pathologic, Proto-Oncogene Proteins c-akt, Receptor, ErbB-2, Signal Transduction, T-Lymphocytes, Transforming Growth Factor beta, Vascular Endothelial Growth Factor A
Added December 3, 2014
2 Communities
1 Members
0 Resources
15 MeSH Terms