Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 32

Publication Record

Connections

Systemic delivery of a Gli inhibitor via polymeric nanocarriers inhibits tumor-induced bone disease.
Vanderburgh JP, Kwakwa KA, Werfel TA, Merkel AR, Gupta MK, Johnson RW, Guelcher SA, Duvall CL, Rhoades JA
(2019) J Control Release 311-312: 257-272
MeSH Terms: Animals, Antineoplastic Agents, Apoptosis, Bone Neoplasms, Cell Line, Tumor, Cell Proliferation, Cell Survival, Drug Carriers, Drug Liberation, Female, Gene Expression Regulation, Neoplastic, Humans, Mammary Neoplasms, Animal, Mesenchymal Stem Cells, Mice, Inbred C57BL, Mice, Knockout, Mice, Nude, Nanoparticles, Osteogenesis, Polymers, Pyridines, Thiophenes, Zinc Finger Protein Gli2
Added March 3, 2020
0 Communities
4 Members
0 Resources
23 MeSH Terms
Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer.
Dushyanthen S, Teo ZL, Caramia F, Savas P, Mintoff CP, Virassamy B, Henderson MA, Luen SJ, Mansour M, Kershaw MH, Trapani JA, Neeson PJ, Salgado R, McArthur GA, Balko JM, Beavis PA, Darcy PK, Loi S
(2017) Nat Commun 8: 606
MeSH Terms: 4-1BB Ligand, Animals, Breast Neoplasms, Cell Line, Tumor, Cell Proliferation, Female, Humans, Immunotherapy, Lymphocytes, Tumor-Infiltrating, MAP Kinase Kinase 1, MAP Kinase Kinase 2, MAP Kinase Signaling System, Mammary Neoplasms, Animal, Mice, OX40 Ligand, Protein Kinase Inhibitors, Pyridones, Pyrimidinones, T-Lymphocyte Subsets, T-Lymphocytes, Triple Negative Breast Neoplasms
Added March 14, 2018
0 Communities
1 Members
0 Resources
21 MeSH Terms
PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses.
Sai J, Owens P, Novitskiy SV, Hawkins OE, Vilgelm AE, Yang J, Sobolik T, Lavender N, Johnson AC, McClain C, Ayers GD, Kelley MC, Sanders M, Mayer IA, Moses HL, Boothby M, Richmond A
(2017) Clin Cancer Res 23: 3371-3384
MeSH Terms: Aminopyridines, Animals, Cell Line, Tumor, Cell Proliferation, Class Ib Phosphatidylinositol 3-Kinase, Female, Humans, Immunity, Cellular, Mammary Neoplasms, Animal, Mice, Morpholines, Neoplasm Metastasis, Phosphoinositide-3 Kinase Inhibitors, Programmed Cell Death 1 Receptor, Protein Kinase Inhibitors, Signal Transduction, Triple Negative Breast Neoplasms, Xenograft Model Antitumor Assays
Added January 4, 2017
2 Communities
4 Members
0 Resources
18 MeSH Terms
Quantitative [F]FMISO PET Imaging Shows Reduction of Hypoxia Following Trastuzumab in a Murine Model of HER2+ Breast Cancer.
Sorace AG, Syed AK, Barnes SL, Quarles CC, Sanchez V, Kang H, Yankeelov TE
(2017) Mol Imaging Biol 19: 130-137
MeSH Terms: Animals, Biomarkers, Tumor, Cell Line, Tumor, Disease Models, Animal, Female, Fluorescent Antibody Technique, Mammary Neoplasms, Animal, Misonidazole, Nitroimidazoles, Positron-Emission Tomography, Receptor, ErbB-2, Trastuzumab, Tumor Burden, Tumor Hypoxia
Added April 6, 2017
0 Communities
1 Members
0 Resources
14 MeSH Terms
An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter.
Huo Y, Su T, Cai Q, Macara IG
(2016) Cell Rep 15: 2089-2096
MeSH Terms: Animals, Bone Morphogenetic Protein Receptors, Type I, Breast Neoplasms, Carcinogenesis, Female, Gene Expression Regulation, Neoplastic, Genetic Testing, Humans, Mammary Neoplasms, Animal, Mice, Transgenic, Muscle Proteins, Nuclear Proteins, Protein-Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Trans-Activators, Williams Syndrome
Added April 3, 2018
0 Communities
2 Members
0 Resources
17 MeSH Terms
mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis.
Morrison MM, Young CD, Wang S, Sobolik T, Sanchez VM, Hicks DJ, Cook RS, Brantley-Sieders DM
(2015) PLoS Genet 11: e1005291
MeSH Terms: Animals, Carrier Proteins, Cell Line, Cell Movement, Cell Survival, Female, Mammary Glands, Animal, Mammary Neoplasms, Animal, Mechanistic Target of Rapamycin Complex 1, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, Inbred C57BL, Mice, Transgenic, Morphogenesis, Multiprotein Complexes, Neoplasm Invasiveness, Neuropeptides, Organ Culture Techniques, Phosphorylation, Protein Kinase C-alpha, Proto-Oncogene Proteins c-akt, Rapamycin-Insensitive Companion of mTOR Protein, TOR Serine-Threonine Kinases, rac1 GTP-Binding Protein
Added April 15, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
IL4 receptor α mediates enhanced glucose and glutamine metabolism to support breast cancer growth.
Venmar KT, Kimmel DW, Cliffel DE, Fingleton B
(2015) Biochim Biophys Acta 1853: 1219-28
MeSH Terms: Animals, Breast Neoplasms, Cell Line, Tumor, Cell Proliferation, Female, Glucose, Glucose Transporter Type 1, Glutamine, Humans, Interleukin-4, Mammary Neoplasms, Animal, Membrane Transport Proteins, Mice, Receptors, Interleukin-4
Added September 28, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Biocompatible mannosylated endosomal-escape nanoparticles enhance selective delivery of short nucleotide sequences to tumor associated macrophages.
Ortega RA, Barham WJ, Kumar B, Tikhomirov O, McFadden ID, Yull FE, Giorgio TD
(2015) Nanoscale 7: 500-10
MeSH Terms: Animals, Biocompatible Materials, Cell Line, Tumor, Cell Survival, Coculture Techniques, Drug Carriers, Endosomes, Female, Fluorescent Dyes, Lung, Lung Neoplasms, Macrophages, Mammary Neoplasms, Animal, Mannose, Mice, Mice, Inbred C57BL, Microscopy, Fluorescence, Nanoparticles, Ovarian Neoplasms, Polymers, RNA, Small Interfering, Transplantation, Homologous, Tumor Microenvironment
Added December 17, 2014
1 Communities
2 Members
0 Resources
23 MeSH Terms
Role of TGF-β signaling in generation of CD39+CD73+ myeloid cells in tumors.
Ryzhov SV, Pickup MW, Chytil A, Gorska AE, Zhang Q, Owens P, Feoktistov I, Moses HL, Novitskiy SV
(2014) J Immunol 193: 3155-64
MeSH Terms: 5'-Nucleotidase, Animals, Antigens, CD, Apyrase, Bone Marrow Cells, Carcinoma, Lewis Lung, Cell Differentiation, Cell Line, Tumor, Cell Movement, Female, Mammary Glands, Animal, Mammary Neoplasms, Animal, Mice, Mice, Inbred C57BL, Mice, Knockout, Myeloid Cells, Protein-Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, T-Lymphocytes, Transforming Growth Factor beta, Tumor Microenvironment, Vascular Endothelial Growth Factor A
Added December 3, 2014
2 Communities
2 Members
0 Resources
24 MeSH Terms
Inhibition of BMP signaling suppresses metastasis in mammary cancer.
Owens P, Pickup MW, Novitskiy SV, Giltnane JM, Gorska AE, Hopkins CR, Hong CC, Moses HL
(2015) Oncogene 34: 2437-49
MeSH Terms: Animals, Bone Morphogenetic Proteins, Female, Fibroblasts, Humans, Lung Neoplasms, Lymphatic Vessels, Macrophages, Mammary Neoplasms, Animal, Mice, Mice, Inbred C57BL, Mice, Transgenic, Pyrazoles, Quinolines, Signal Transduction, Tumor Microenvironment
Added July 8, 2014
2 Communities
4 Members
0 Resources
16 MeSH Terms