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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 18

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GSK3-mediated instability of tubulin polymers is responsible for the failure of immature CD4+CD8+ thymocytes to polarize their MTOC in response to TCR stimulation.
Cunningham NR, Hinchcliff EM, Kutyavin VI, Beck T, Reid WA, Punt JA
(2011) Int Immunol 23: 693-700
MeSH Terms: Aminophenols, Animals, Blotting, Western, CD4 Antigens, CD8 Antigens, Cell Differentiation, Enzyme Inhibitors, Female, Flow Cytometry, Gene Expression Regulation, Developmental, Glycogen Synthase Kinase 3, Lymphocyte Activation, Maleimides, Mice, Mice, Inbred C57BL, Microtubule-Organizing Center, Microtubules, Polymerization, Receptors, Antigen, T-Cell, Signal Transduction, T-Lymphocytes, Thymocytes, Tubulin
Added January 11, 2016
0 Communities
1 Members
0 Resources
23 MeSH Terms
Thiol-based, site-specific and covalent immobilization of biomolecules for single-molecule experiments.
Zimmermann JL, Nicolaus T, Neuert G, Blank K
(2010) Nat Protoc 5: 975-85
MeSH Terms: Binding Sites, Enzymes, Immobilized, Fluorescence, Immobilized Proteins, Maleimides, Microscopy, Atomic Force, Nucleic Acids, Polyethylene Glycols, Succinimides, Sulfhydryl Compounds
Added June 2, 2013
0 Communities
1 Members
0 Resources
10 MeSH Terms
A new class of molecular targeted radioprotectors: GSK-3beta inhibitors.
Thotala DK, Geng L, Dickey AK, Hallahan DE, Yazlovitskaya EM
(2010) Int J Radiat Oncol Biol Phys 76: 557-65
MeSH Terms: Aminophenols, Animals, Apoptosis, Caspase 3, Cell Line, Cell Survival, Glycogen Synthase Kinase 3, Glycogen Synthase Kinase 3 beta, In Situ Nick-End Labeling, Indoles, Intestines, Maleimides, Mice, Mice, Inbred C57BL, Radiation Injuries, Experimental, Radiation-Protective Agents, Rats, bcl-2-Associated X Protein, beta Catenin
Added August 21, 2013
0 Communities
1 Members
0 Resources
19 MeSH Terms
Light-guided surface engineering for biomedical applications.
Jayagopal A, Stone GP, Haselton FR
(2008) Bioconjug Chem 19: 792-6
MeSH Terms: 3T3 Cells, Animals, Antibodies, Monoclonal, Bacteriophage M13, Biosensing Techniques, Cell Adhesion, Cross-Linking Reagents, Fluorescein-5-isothiocyanate, Fluorescent Dyes, Glass, Immunoglobulin E, Light, Maleimides, Mice, Photobleaching, Photochemistry, Polylysine, Surface Properties, Tissue Engineering
Added May 27, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
The role of proline-rich protein tyrosine kinase 2 in differentiation-dependent signaling in human epidermal keratinocytes.
Schindler EM, Baumgartner M, Gribben EM, Li L, Efimova T
(2007) J Invest Dermatol 127: 1094-106
MeSH Terms: Calcium, Cell Differentiation, Cell Nucleus, Cells, Cultured, Epidermal Cells, Epidermis, Focal Adhesion Kinase 2, Gene Expression Regulation, Humans, Indoles, Keratinocytes, Maleimides, Protein Kinase C, Protein Precursors, Proto-Oncogene Proteins c-fos, Proto-Oncogene Proteins c-jun, Signal Transduction, Tetradecanoylphorbol Acetate
Added May 30, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
Thrombin modulates the expression of a set of genes including thrombospondin-1 in human microvascular endothelial cells.
McLaughlin JN, Mazzoni MR, Cleator JH, Earls L, Perdigoto AL, Brooks JD, Muldowney JA, Vaughan DE, Hamm HE
(2005) J Biol Chem 280: 22172-80
MeSH Terms: Adenosine Diphosphate, Algorithms, Amides, Apoptosis, Cells, Cultured, Cluster Analysis, Culture Media, DNA Primers, DNA, Complementary, Dose-Response Relationship, Drug, Electric Impedance, Endothelium, Vascular, Enzyme-Linked Immunosorbent Assay, Extracellular Matrix, GTP-Binding Protein alpha Subunits, Gi-Go, GTP-Binding Protein alpha Subunits, Gq-G11, Gene Expression Regulation, Humans, Indoles, Maleimides, Microcirculation, Models, Biological, Nucleic Acid Hybridization, Oligonucleotide Array Sequence Analysis, Peptides, Pertussis Toxin, Promoter Regions, Genetic, Protein Binding, Pyridines, RNA, Receptor, PAR-1, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Thrombin, Thrombospondin 1, Time Factors, Umbilical Veins, Up-Regulation
Added December 10, 2013
0 Communities
1 Members
0 Resources
38 MeSH Terms
Regulation and function of COX-2 gene expression in isolated gastric parietal cells.
Pausawasdi N, Ramamoorthy S, Crofford LJ, Askari FK, Todisco A
(2002) Am J Physiol Gastrointest Liver Physiol 282: G1069-78
MeSH Terms: Animals, Carbachol, Cells, Cultured, Cholinergic Agonists, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors, Dogs, Enzyme Inhibitors, Gene Expression Regulation, Enzymologic, Histamine, Imidazoles, Indoles, Isoenzymes, Maleimides, NF-kappa B, Nitrobenzenes, Parietal Cells, Gastric, Prostaglandin-Endoperoxide Synthases, Prostaglandins, Pyridines, Sulfonamides
Added September 18, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
Inactivation of prostaglandin endoperoxide synthase (PGHS) by N-(substituted)maleimides.
Kalgutkar AS, Crews BC, Marnett LJ
(1997) Adv Exp Med Biol 407: 79-85
MeSH Terms: Caprylates, Cyclooxygenase Inhibitors, Humans, Maleimides, Peroxidases, Prostaglandin-Endoperoxide Synthases, Substrate Specificity, Trypsin
Added March 5, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Effects of cysteine-to-serine mutations on structural and functional properties of prostaglandin endoperoxide synthase.
Smith CJ, Marnett LJ
(1996) Arch Biochem Biophys 335: 342-50
MeSH Terms: Animals, COS Cells, Cross-Linking Reagents, Cyclooxygenase Inhibitors, Cysteine, Flurbiprofen, Kinetics, Maleimides, Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase, Methionine, Molecular Weight, Mutagenesis, Site-Directed, Prostaglandin-Endoperoxide Synthases, Recombinant Proteins, Sheep, Structure-Activity Relationship, Sulfhydryl Reagents
Added March 5, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Design, synthesis, and biochemical evaluation of N-substituted maleimides as inhibitors of prostaglandin endoperoxide synthases.
Kalgutkar AS, Crews BC, Marnett LJ
(1996) J Med Chem 39: 1692-703
MeSH Terms: Animals, Chromatography, High Pressure Liquid, Cyclooxygenase Inhibitors, Drug Design, Hemin, Male, Maleimides, Sheep, Structure-Activity Relationship
Added March 5, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms