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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 54

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Control of antiviral innate immune response by protein geranylgeranylation.
Yang S, Harding AT, Sweeney C, Miao D, Swan G, Zhou C, Jiang Z, Fitzgerald KA, Hammer G, Bergo MO, Kroh HK, Lacy DB, Sun C, Glogauer M, Que LG, Heaton NS, Wang D
(2019) Sci Adv 5: eaav7999
MeSH Terms: Adaptor Proteins, Signal Transducing, Alkyl and Aryl Transferases, Animals, Endoplasmic Reticulum, Female, Humans, Immunity, Innate, Macrophages, Alveolar, Male, Mice, Knockout, Neuropeptides, Orthomyxoviridae Infections, Protein Prenylation, Receptor-Interacting Protein Serine-Threonine Kinases, Tripartite Motif Proteins, Ubiquitin-Protein Ligases, rac GTP-Binding Proteins, rac1 GTP-Binding Protein
Added March 24, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Efferocytosis-induced prostaglandin E2 production impairs alveolar macrophage effector functions during Streptococcus pneumoniae infection.
Salina AC, Souza TP, Serezani CH, Medeiros AI
(2017) Innate Immun 23: 219-227
MeSH Terms: Animals, Apoptosis, Bacteriolysis, Cyclic AMP, Cyclic AMP-Dependent Protein Kinases, Dinoprostone, Female, Homeostasis, Humans, Hydrogen Peroxide, Jurkat Cells, Macrophages, Alveolar, Phagocytosis, Pneumococcal Infections, Rats, Rats, Wistar, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP4 Subtype, Signal Transduction, Streptococcus pneumoniae
Added May 4, 2017
0 Communities
1 Members
0 Resources
20 MeSH Terms
Increased lethality and defective pulmonary clearance of Streptococcus pneumoniae in microsomal prostaglandin E synthase-1-knockout mice.
Dolan JM, Weinberg JB, O'Brien E, Abashian A, Procario MC, Aronoff DM, Crofford LJ, Peters-Golden M, Ward L, Mancuso P
(2016) Am J Physiol Lung Cell Mol Physiol 310: L1111-20
MeSH Terms: Animals, Cyclooxygenase 1, Cytokines, Dinoprostone, Female, Immunity, Innate, Lung, Macrophages, Alveolar, Membrane Proteins, Mice, Inbred C57BL, Mice, Knockout, Microsomes, Nitric Oxide, Pneumonia, Pneumococcal, Streptococcus pneumoniae
Added June 2, 2017
0 Communities
2 Members
0 Resources
15 MeSH Terms
Chronic NF-κB activation links COPD and lung cancer through generation of an immunosuppressive microenvironment in the lungs.
Zaynagetdinov R, Sherrill TP, Gleaves LA, Hunt P, Han W, McLoed AG, Saxon JA, Tanjore H, Gulleman PM, Young LR, Blackwell TS
(2016) Oncotarget 7: 5470-82
MeSH Terms: Animals, Blotting, Western, CD8-Positive T-Lymphocytes, Cells, Cultured, Epithelium, Female, Flow Cytometry, Humans, I-kappa B Kinase, Immunosuppressive Agents, Inflammation, Interleukin-10, Lung, Lung Neoplasms, Macrophages, Alveolar, Male, Mice, Mice, Transgenic, NF-kappa B, Pulmonary Disease, Chronic Obstructive, RNA, Messenger, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, T-Lymphocytes, Regulatory, Transforming Growth Factor beta
Added February 22, 2016
1 Communities
1 Members
0 Resources
26 MeSH Terms
Lipoxin Inhibits Fungal Uptake by Macrophages and Reduces the Severity of Acute Pulmonary Infection Caused by Paracoccidioides brasiliensis.
Ribeiro LR, Loures FV, de Araújo EF, Feriotti C, Costa TA, Serezani CH, Jancar S, Calich VL
(2015) Mediators Inflamm 2015: 852574
MeSH Terms: Acetates, Animals, Arachidonate 5-Lipoxygenase, Dinoprostone, Inflammation Mediators, Leukotriene Antagonists, Leukotriene C4, Lipoxins, Macrophages, Alveolar, Male, Mice, Mice, 129 Strain, Mice, Inbred A, Mice, Knockout, Paracoccidioides, Paracoccidioidomycosis, Quinolines, Receptors, Leukotriene, Receptors, Pattern Recognition
Added May 4, 2017
0 Communities
1 Members
0 Resources
19 MeSH Terms
Molecular imaging of folate receptor β-positive macrophages during acute lung inflammation.
Han W, Zaynagetdinov R, Yull FE, Polosukhin VV, Gleaves LA, Tanjore H, Young LR, Peterson TE, Manning HC, Prince LS, Blackwell TS
(2015) Am J Respir Cell Mol Biol 53: 50-9
MeSH Terms: Acute Disease, Animals, Chemokine CCL2, Escherichia coli, Fluorescent Dyes, Folate Receptor 2, Gene Expression Regulation, Lipopolysaccharides, Macrophages, Alveolar, Mice, Mice, Knockout, Molecular Imaging, Pneumonia, Receptors, CCR2
Added December 8, 2014
2 Communities
4 Members
0 Resources
14 MeSH Terms
Differential role for p120-catenin in regulation of TLR4 signaling in macrophages.
Yang Z, Sun D, Yan Z, Reynolds AB, Christman JW, Minshall RD, Malik AB, Zhang Y, Hu G
(2014) J Immunol 193: 1931-41
MeSH Terms: Acute Lung Injury, Adaptor Proteins, Vesicular Transport, Animals, Bronchoalveolar Lavage Fluid, Catenins, Cells, Cultured, Endocytosis, Interferon Regulatory Factor-3, Interferon-beta, Interleukin-6, Leukocyte Count, Lipopolysaccharides, Macrophages, Alveolar, Male, Mice, Mice, Inbred C57BL, Myeloid Differentiation Factor 88, NF-kappa B, Neutrophils, Protein Transport, RNA Interference, Signal Transduction, Toll-Like Receptor 2, Toll-Like Receptor 3, Toll-Like Receptor 4, Tumor Necrosis Factor-alpha, rhoA GTP-Binding Protein
Added May 2, 2016
1 Communities
1 Members
0 Resources
27 MeSH Terms
IκB kinase activity drives fetal lung macrophage maturation along a non-M1/M2 paradigm.
Stouch AN, Zaynagetdinov R, Barham WJ, Stinnett AM, Slaughter JC, Yull FE, Hoffman HM, Blackwell TS, Prince LS
(2014) J Immunol 193: 1184-93
MeSH Terms: Animals, Animals, Newborn, Biomarkers, Cell Differentiation, Enzyme Activation, Female, Gene Expression Regulation, Developmental, Gene Expression Regulation, Enzymologic, Humans, I-kappa B Kinase, Immunophenotyping, Inflammation, Lung Diseases, Macrophage Activation, Macrophages, Alveolar, Macrophages, Peritoneal, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic
Added December 17, 2014
1 Communities
3 Members
0 Resources
20 MeSH Terms
Proinflammatory responses of heme in alveolar macrophages: repercussion in lung hemorrhagic episodes.
Simões RL, Arruda MA, Canetti C, Serezani CH, Fierro IM, Barja-Fidalgo C
(2013) Mediators Inflamm 2013: 946878
MeSH Terms: Animals, Heme, Humans, Inflammation, Macrophages, Alveolar, Metabolic Syndrome, Mice, Pneumonia, Rats
Added May 4, 2017
0 Communities
1 Members
0 Resources
9 MeSH Terms
Prostaglandin E2-induced changes in alveolar macrophage scavenger receptor profiles differentially alter phagocytosis of Pseudomonas aeruginosa and Staphylococcus aureus post-bone marrow transplant.
Domingo-Gonzalez R, Katz S, Serezani CH, Moore TA, Levine AM, Moore BB
(2013) J Immunol 190: 5809-17
MeSH Terms: Animals, Bone Marrow Transplantation, Dinoprostone, Gene Expression Regulation, Macrophages, Alveolar, Mice, MicroRNAs, Phagocytosis, Pseudomonas Infections, Pseudomonas aeruginosa, Receptors, Immunologic, Receptors, Scavenger, Scavenger Receptors, Class A, Staphylococcal Infections, Staphylococcus aureus
Added May 4, 2017
0 Communities
1 Members
0 Resources
15 MeSH Terms