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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 155

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Apoptosis signal-regulating kinase 1 (ASK1) inhibition reduces endothelial cytokine production without improving permeability after toll-like receptor 4 (TLR4) challenge.
Miller MR, Koch SR, Choi H, Lamb FS, Stark RJ
(2021) Transl Res 235: 115-128
MeSH Terms: Cells, Cultured, Cytokines, Endothelial Cells, Humans, JNK Mitogen-Activated Protein Kinases, MAP Kinase Kinase Kinase 5, MAP Kinase Signaling System, Nitric Oxide Synthase Type III, Permeability, Toll-Like Receptor 4, p38 Mitogen-Activated Protein Kinases
Added April 16, 2021
0 Communities
1 Members
0 Resources
11 MeSH Terms
BRAF molecular testing in cytopathology: Implications for diagnosis, prognosis, and targeted therapeutics.
Bergdorf KN, Lee LA, Weiss VL
(2020) Cancer Cytopathol 128: 9-11
MeSH Terms: Antineoplastic Agents, Genetic Testing, Humans, MAP Kinase Signaling System, Molecular Targeted Therapy, Mutation, Neoplasms, Phosphorylation, Precision Medicine, Prognosis, Proto-Oncogene Proteins B-raf
Added March 3, 2020
0 Communities
1 Members
0 Resources
11 MeSH Terms
Activation of Nrf2 attenuates delayed gastric emptying in obesity induced diabetic (T2DM) female mice.
Sampath C, Sprouse JC, Freeman ML, Gangula PR
(2019) Free Radic Biol Med 135: 132-143
MeSH Terms: Acrolein, Animals, Antioxidants, Diabetes Complications, Diabetes Mellitus, Type 2, Diet, High-Fat, Gastric Emptying, Gastroparesis, Humans, MAP Kinase Signaling System, Mice, Muscle Relaxation, NF-E2-Related Factor 2, Nitric Oxide Synthase Type I, Obesity, Stomach, p38 Mitogen-Activated Protein Kinases
Added March 3, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification.
Perry NA, Kaoud TS, Ortega OO, Kaya AI, Marcus DJ, Pleinis JM, Berndt S, Chen Q, Zhan X, Dalby KN, Lopez CF, Iverson TM, Gurevich VV
(2019) Proc Natl Acad Sci U S A 116: 810-815
MeSH Terms: MAP Kinase Kinase 4, MAP Kinase Kinase 7, MAP Kinase Signaling System, Mitogen-Activated Protein Kinase 10, Models, Biological, Phosphorylation, Software, beta-Arrestin 2
Added April 1, 2019
0 Communities
2 Members
0 Resources
MeSH Terms
BRAF internal deletions and resistance to BRAF/MEK inhibitor therapy.
Johnson DB, Childress MA, Chalmers ZR, Frampton GM, Ali SM, Rubinstein SM, Fabrizio D, Ross JS, Balasubramanian S, Miller VA, Stephens PJ, Sosman JA, Lovly CM
(2018) Pigment Cell Melanoma Res 31: 432-436
MeSH Terms: Adult, Amino Acid Substitution, Base Sequence, Drug Resistance, Neoplasm, Female, Humans, Imidazoles, MAP Kinase Signaling System, Melanoma, Mutation, Missense, Oximes, Protein Kinase Inhibitors, Proto-Oncogene Proteins B-raf, Pyridones, Pyrimidinones, Sequence Deletion
Added September 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Endothelial nitric oxide synthase modulates Toll-like receptor 4-mediated IL-6 production and permeability via nitric oxide-independent signaling.
Stark RJ, Koch SR, Choi H, Mace EH, Dikalov SI, Sherwood ER, Lamb FS
(2018) FASEB J 32: 945-956
MeSH Terms: Capillary Permeability, Cells, Cultured, Chronic Disease, Endothelial Cells, Gene Expression Regulation, Enzymologic, Humans, Imidazoles, Interleukin-6, Lipopolysaccharides, MAP Kinase Signaling System, Nitric Oxide, Nitric Oxide Synthase Type III, Pyridines, Toll-Like Receptor 4, Vasculitis, p38 Mitogen-Activated Protein Kinases
Added October 27, 2017
0 Communities
3 Members
0 Resources
16 MeSH Terms
Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer.
Dushyanthen S, Teo ZL, Caramia F, Savas P, Mintoff CP, Virassamy B, Henderson MA, Luen SJ, Mansour M, Kershaw MH, Trapani JA, Neeson PJ, Salgado R, McArthur GA, Balko JM, Beavis PA, Darcy PK, Loi S
(2017) Nat Commun 8: 606
MeSH Terms: 4-1BB Ligand, Animals, Breast Neoplasms, Cell Line, Tumor, Cell Proliferation, Female, Humans, Immunotherapy, Lymphocytes, Tumor-Infiltrating, MAP Kinase Kinase 1, MAP Kinase Kinase 2, MAP Kinase Signaling System, Mammary Neoplasms, Animal, Mice, OX40 Ligand, Protein Kinase Inhibitors, Pyridones, Pyrimidinones, T-Lymphocyte Subsets, T-Lymphocytes, Triple Negative Breast Neoplasms
Added March 14, 2018
0 Communities
1 Members
0 Resources
21 MeSH Terms
The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1.
Almohazey D, Lo YH, Vossler CV, Simmons AJ, Hsieh JJ, Bucar EB, Schumacher MA, Hamilton KE, Lau KS, Shroyer NF, Frey MR
(2017) Cell Death Differ 24: 855-865
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Communication, Cell Count, Cell Differentiation, Extracellular Signal-Regulated MAP Kinases, Female, Gene Expression Regulation, HT29 Cells, Humans, Ileum, MAP Kinase Signaling System, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Paneth Cells, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Receptor, ErbB-3, Receptors, G-Protein-Coupled, Stem Cell Niche, Stem Cells
Added October 16, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Impaired coordination between signaling pathways is revealed in human colorectal cancer using single-cell mass cytometry of archival tissue blocks.
Simmons AJ, Scurrah CR, McKinley ET, Herring CA, Irish JM, Washington MK, Coffey RJ, Lau KS
(2016) Sci Signal 9: rs11
MeSH Terms: Animals, Colorectal Neoplasms, Female, Humans, Image Cytometry, MAP Kinase Signaling System, Male, Mass Spectrometry, Mice, Neoplasm Proteins, Paraffin Embedding
Added October 19, 2016
3 Communities
4 Members
0 Resources
11 MeSH Terms
The MAPK Pathway Regulates Intrinsic Resistance to BET Inhibitors in Colorectal Cancer.
Ma Y, Wang L, Neitzel LR, Loganathan SN, Tang N, Qin L, Crispi EE, Guo Y, Knapp S, Beauchamp RD, Lee E, Wang J
(2017) Clin Cancer Res 23: 2027-2037
MeSH Terms: Animals, Antineoplastic Agents, Apoptosis, Cell Line, Tumor, Cell Proliferation, Colorectal Neoplasms, Drug Resistance, Neoplasm, Female, Gene Expression Regulation, Neoplastic, Humans, MAP Kinase Signaling System, Mice, Mice, Nude, Nuclear Proteins, Real-Time Polymerase Chain Reaction, Transcription Factors, Xenograft Model Antitumor Assays
Added November 19, 2016
0 Communities
4 Members
0 Resources
17 MeSH Terms