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Results: 1 to 7 of 7

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Apoptosis signal-regulating kinase 1 (ASK1) inhibition reduces endothelial cytokine production without improving permeability after toll-like receptor 4 (TLR4) challenge.
Miller MR, Koch SR, Choi H, Lamb FS, Stark RJ
(2021) Transl Res 235: 115-128
MeSH Terms: Cells, Cultured, Cytokines, Endothelial Cells, Humans, JNK Mitogen-Activated Protein Kinases, MAP Kinase Kinase Kinase 5, MAP Kinase Signaling System, Nitric Oxide Synthase Type III, Permeability, Toll-Like Receptor 4, p38 Mitogen-Activated Protein Kinases
Added April 16, 2021
0 Communities
1 Members
0 Resources
11 MeSH Terms
Apoptosis signal-regulating kinase 1 activation by Nox1-derived oxidants is required for TNF╬▒ receptor endocytosis.
Choi H, Stark RJ, Raja BS, Dikalova A, Lamb FS
(2019) Am J Physiol Heart Circ Physiol 316: H1528-H1537
MeSH Terms: Animals, Aorta, Thoracic, Cells, Cultured, Endocytosis, MAP Kinase Kinase Kinase 5, Mice, Inbred C57BL, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, NADPH Oxidase 1, Receptors, Tumor Necrosis Factor, Type I, Signal Transduction, Superoxides, Tumor Necrosis Factor-alpha
Added April 3, 2019
0 Communities
1 Members
0 Resources
13 MeSH Terms
Cleavage of arrestin-3 by caspases attenuates cell death by precluding arrestin-dependent JNK activation.
Kook S, Vishnivetskiy SA, Gurevich VV, Gurevich EV
(2019) Cell Signal 54: 161-169
MeSH Terms: Animals, Apoptosis, Arrestins, COS Cells, Caspases, Chlorocebus aethiops, Etoposide, MAP Kinase Kinase 4, MAP Kinase Kinase Kinase 5
Added March 18, 2020
0 Communities
1 Members
0 Resources
9 MeSH Terms
Assembly Dynamics and Stoichiometry of the Apoptosis Signal-regulating Kinase (ASK) Signalosome in Response to Electrophile Stress.
Federspiel JD, Codreanu SG, Palubinsky AM, Winland AJ, Betanzos CM, McLaughlin B, Liebler DC
(2016) Mol Cell Proteomics 15: 1947-61
MeSH Terms: 14-3-3 Proteins, Aldehydes, Epitopes, HEK293 Cells, Humans, Isotope Labeling, MAP Kinase Kinase Kinase 5, MAP Kinase Kinase Kinases, Mass Spectrometry, Protein Interaction Maps, Proteomics, Signal Transduction
Added April 25, 2016
1 Communities
1 Members
0 Resources
12 MeSH Terms
Arrestin-3 binds c-Jun N-terminal kinase 1 (JNK1) and JNK2 and facilitates the activation of these ubiquitous JNK isoforms in cells via scaffolding.
Kook S, Zhan X, Kaoud TS, Dalby KN, Gurevich VV, Gurevich EV
(2013) J Biol Chem 288: 37332-42
MeSH Terms: Animals, Arrestins, COS Cells, Cell Proliferation, Cell Survival, Chlorocebus aethiops, Enzyme Activation, Isoenzymes, MAP Kinase Kinase 7, MAP Kinase Kinase Kinase 5, MAP Kinase Signaling System, Mice, Mice, Knockout, Mitogen-Activated Protein Kinase 8, Mitogen-Activated Protein Kinase 9, Phosphorylation, Protein Binding
Added February 12, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Silent scaffolds: inhibition OF c-Jun N-terminal kinase 3 activity in cell by dominant-negative arrestin-3 mutant.
Breitman M, Kook S, Gimenez LE, Lizama BN, Palazzo MC, Gurevich EV, Gurevich VV
(2012) J Biol Chem 287: 19653-64
MeSH Terms: Animals, Arrestins, Biological Assay, COS Cells, Chlorocebus aethiops, Enzyme Activation, Humans, MAP Kinase Kinase 4, MAP Kinase Kinase Kinase 5, MAP Kinase Signaling System, Mitogen-Activated Protein Kinase 10, Mutation, Phosphorylation, Protein Binding
Added December 10, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
Identification of arrestin-3-specific residues necessary for JNK3 kinase activation.
Seo J, Tsakem EL, Breitman M, Gurevich VV
(2011) J Biol Chem 286: 27894-901
MeSH Terms: Animals, Arrestins, COS Cells, Cattle, Chlorocebus aethiops, Enzyme Activation, MAP Kinase Kinase Kinase 5, Mitogen-Activated Protein Kinase 10, Phosphorylation, Protein Structure, Secondary, Protein Structure, Tertiary
Added December 10, 2013
0 Communities
1 Members
0 Resources
11 MeSH Terms