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HLA-DR cancer cells expression correlates with T cell infiltration and is enriched in lung adenocarcinoma with indolent behavior.
Senosain MF, Zou Y, Novitskaya T, Vasiukov G, Balar AB, Rowe DJ, Doxie DB, Lehman JM, Eisenberg R, Maldonado F, Zijlstra A, Novitskiy SV, Irish JM, Massion PP
(2021) Sci Rep 11: 14424
MeSH Terms: Adenocarcinoma of Lung, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, HLA-DR Antigens, Humans, Leukocytes, Mononuclear
Added August 31, 2021
3 Communities
1 Members
0 Resources
6 MeSH Terms
Diagnostic Yield of Digital Tomosynthesis-assisted Navigational Bronchoscopy for Indeterminate Lung Nodules.
Katsis J, Roller L, Aboudara M, Pannu J, Chen H, Johnson J, Lentz RJ, Rickman O, Maldonado F
(2021) J Bronchology Interv Pulmonol 28: 255-261
MeSH Terms: Bronchoscopy, Electromagnetic Phenomena, Humans, Lung, Lung Neoplasms, Pneumothorax, Retrospective Studies
Added May 17, 2021
0 Communities
1 Members
0 Resources
7 MeSH Terms
Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation.
Healey DCC, Cephus JY, Barone SM, Chowdhury NU, Dahunsi DO, Madden MZ, Ye X, Yu X, Olszewski K, Young K, Gerriets VA, Siska PJ, Dworski R, Hemler J, Locasale JW, Poyurovsky MV, Peebles RS, Irish JM, Newcomb DC, Rathmell JC
(2021) J Immunol 206: 1127-1139
MeSH Terms: Adult, Alternaria, Animals, Asthma, Biomarkers, Blood Glucose, Bronchoalveolar Lavage Fluid, Case-Control Studies, Cells, Cultured, Dexamethasone, Disease Models, Animal, Drug Synergism, Female, Glucose Transporter Type 1, Glutaminase, Glutamine, Healthy Volunteers, Humans, Immunosuppressive Agents, Lung, Male, Mice, Middle Aged, Primary Cell Culture, Pyroglyphidae, Th17 Cells, Th2 Cells, Young Adult
Added March 26, 2021
3 Communities
1 Members
0 Resources
28 MeSH Terms
Reply.
Aboudara M, Roller L, Rickman O, Lentz RJ, Pannu J, Chen H, Maldonado F
(2021) Respirology 26: 126
MeSH Terms: Bronchoscopy, Humans, Lung, Radiography
Added May 17, 2021
0 Communities
1 Members
0 Resources
4 MeSH Terms
Selective inhibition of mTORC1 in tumor vessels increases antitumor immunity.
Wang S, Raybuck A, Shiuan E, Cho SH, Wang Q, Brantley-Sieders DM, Edwards D, Allaman MM, Nathan J, Wilson KT, DeNardo D, Zhang S, Cook R, Boothby M, Chen J
(2020) JCI Insight 5:
MeSH Terms: Animals, Antineoplastic Agents, Breast Neoplasms, Carcinoma, Lewis Lung, Disease Models, Animal, Endothelium, Vascular, Everolimus, Female, Humans, Lymphocytes, Tumor-Infiltrating, Mechanistic Target of Rapamycin Complex 1, Mice, Mice, Inbred C57BL, Signal Transduction
Added September 17, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
Cryobiopsy With Radial UltraSound Guidance (CYRUS): A Pilot Randomized Controlled Study.
Pannu JK, Roller LJ, Lentz RJ, Rickman OB, Aboudara MC, Chen H, Maldonado F
(2021) J Bronchology Interv Pulmonol 28: 21-28
MeSH Terms: Biopsy, Bronchoscopy, Humans, Lung, Pilot Projects, Prospective Studies, Ultrasonography
Added May 17, 2021
0 Communities
1 Members
0 Resources
7 MeSH Terms
N-[F]-Fluoroacetylcrizotinib: A potentially potent and selective PET tracer for molecular imaging of non-small cell lung cancer.
Buck JR, Saleh S, Claus T, Lovly C, Hight MR, Nickels ML, Noor Tantawy M, Charles Manning H
(2020) Bioorg Med Chem Lett 30: 127257
MeSH Terms: Anaplastic Lymphoma Kinase, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Cell Proliferation, Crizotinib, Dose-Response Relationship, Drug, Fluorine Radioisotopes, Humans, Lung Neoplasms, Molecular Imaging, Molecular Structure, Positron-Emission Tomography, Protein Kinase Inhibitors, Structure-Activity Relationship
Added September 10, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
Enhanced Expression of Catalase in Mitochondria Modulates NF-κB-Dependent Lung Inflammation through Alteration of Metabolic Activity in Macrophages.
Han W, Fessel JP, Sherrill T, Kocurek EG, Yull FE, Blackwell TS
(2020) J Immunol 205: 1125-1134
MeSH Terms: Animals, Bone Marrow, Catalase, Lung, Macrophages, Mice, Mice, Inbred C57BL, Mice, Transgenic, Mitochondria, NAD, NF-kappa B, Pneumonia, Reactive Oxygen Species, Signal Transduction
Added July 28, 2020
1 Communities
0 Members
0 Resources
14 MeSH Terms
Microvascular disease confers additional risk to COVID-19 infection.
Bale BF, Doneen AL, Vigerust DJ
(2020) Med Hypotheses 144: 109999
MeSH Terms: Adult, Aging, COVID-19, Cardiovascular Diseases, Child, Diabetes Mellitus, Disease Susceptibility, Humans, Hydrogen Peroxide, Hypertension, Hypochlorous Acid, Immunity, Innate, Lung, Microcirculation, Microvessels, Neutrophils, Pandemics, Peroxidase, Risk Factors, United States
Added June 25, 2020
0 Communities
1 Members
0 Resources
20 MeSH Terms
Vulnerability of drug-resistant EML4-ALK rearranged lung cancer to transcriptional inhibition.
Paliouras AR, Buzzetti M, Shi L, Donaldson IJ, Magee P, Sahoo S, Leong HS, Fassan M, Carter M, Di Leva G, Krebs MG, Blackhall F, Lovly CM, Garofalo M
(2020) EMBO Mol Med 12: e11099
MeSH Terms: Animals, Carcinoma, Non-Small-Cell Lung, Drug Resistance, Neoplasm, Female, Humans, Lung Neoplasms, Mice, Oncogene Proteins, Fusion, Protein Kinase Inhibitors, Transcription, Genetic
Added September 10, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms