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N-[F]-Fluoroacetylcrizotinib: A potentially potent and selective PET tracer for molecular imaging of non-small cell lung cancer.
Buck JR, Saleh S, Claus T, Lovly C, Hight MR, Nickels ML, Noor Tantawy M, Charles Manning H
(2020) Bioorg Med Chem Lett 30: 127257
MeSH Terms: Anaplastic Lymphoma Kinase, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Cell Proliferation, Crizotinib, Dose-Response Relationship, Drug, Fluorine Radioisotopes, Humans, Lung Neoplasms, Molecular Imaging, Molecular Structure, Positron-Emission Tomography, Protein Kinase Inhibitors, Structure-Activity Relationship
Added September 10, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
Host deficiency in ephrin-A1 inhibits breast cancer metastasis.
Shiuan E, Inala A, Wang S, Song W, Youngblood V, Chen J, Brantley-Sieders DM
(2020) F1000Res 9: 217
MeSH Terms: Animals, Ephrin-A1, Lung Neoplasms, Mice, Mice, Knockout, Neoplasm Metastasis, Neoplasm Recurrence, Local, Tumor Microenvironment
Added May 29, 2020
1 Communities
0 Members
0 Resources
8 MeSH Terms
Expanding Access to Lung Cancer Clinical Trials by Reducing the Use of Restrictive Exclusion Criteria: Perspectives of a Multistakeholder Working Group.
Forde PM, Bonomi P, Shaw A, Blumenthal GM, Ferris A, Patel C, Melemed A, Basu Roy U, Ramamoorthy A, Liu Q, Burns T, Gainor JF, Lovly C, Piotrowska Z, Lehman J, Selig W
(2020) Clin Lung Cancer 21: 295-307
MeSH Terms: Clinical Trials as Topic, Eligibility Determination, Humans, Lung Neoplasms, Patient Selection, Stakeholder Participation
Added March 31, 2020
0 Communities
2 Members
0 Resources
6 MeSH Terms
New Approaches to SCLC Therapy: From the Laboratory to the Clinic.
Poirier JT, George J, Owonikoko TK, Berns A, Brambilla E, Byers LA, Carbone D, Chen HJ, Christensen CL, Dive C, Farago AF, Govindan R, Hann C, Hellmann MD, Horn L, Johnson JE, Ju YS, Kang S, Krasnow M, Lee J, Lee SH, Lehman J, Lok B, Lovly C, MacPherson D, McFadden D, Minna J, Oser M, Park K, Park KS, Pommier Y, Quaranta V, Ready N, Sage J, Scagliotti G, Sos ML, Sutherland KD, Travis WD, Vakoc CR, Wait SJ, Wistuba I, Wong KK, Zhang H, Daigneault J, Wiens J, Rudin CM, Oliver TG
(2020) J Thorac Oncol 15: 520-540
MeSH Terms: Humans, Laboratories, Lung Neoplasms, Neoplasm Recurrence, Local, Precision Medicine, Small Cell Lung Carcinoma
Added March 18, 2020
0 Communities
3 Members
0 Resources
6 MeSH Terms
Monitoring Therapeutic Response and Resistance: Analysis of Circulating Tumor DNA in Patients With ALK+ Lung Cancer.
Horn L, Whisenant JG, Wakelee H, Reckamp KL, Qiao H, Leal TA, Du L, Hernandez J, Huang V, Blumenschein GR, Waqar SN, Patel SP, Nieva J, Oxnard GR, Sanborn RE, Shaffer T, Garg K, Holzhausen A, Harrow K, Liang C, Lim LP, Li M, Lovly CM
(2019) J Thorac Oncol 14: 1901-1911
MeSH Terms: Adult, Aged, Aged, 80 and over, Anaplastic Lymphoma Kinase, Carcinoma, Non-Small-Cell Lung, Circulating Tumor DNA, Drug Resistance, Neoplasm, Female, Humans, Lung Neoplasms, Male, Middle Aged, Mutation, Oncogene Proteins, Fusion, Piperazines, Prognosis, Protein Kinase Inhibitors, Pyridazines
Added March 18, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Improved diagnostic yield for lung nodules with digital tomosynthesis-corrected navigational bronchoscopy: Initial experience with a novel adjunct.
Aboudara M, Roller L, Rickman O, Lentz RJ, Pannu J, Chen H, Maldonado F
(2020) Respirology 25: 206-213
MeSH Terms: Aged, Bronchoscopy, Female, Fluoroscopy, Humans, Image-Guided Biopsy, Lung, Lung Neoplasms, Male, Middle Aged, Multiple Pulmonary Nodules, Pneumothorax, Retrospective Studies, Tomography, X-Ray Computed, Ultrasonography
Added May 17, 2021
0 Communities
1 Members
0 Resources
15 MeSH Terms
Improved Prognosis and Increased Tumor-Infiltrating Lymphocytes in Patients Who Have SCLC With Neurologic Paraneoplastic Syndromes.
Iams WT, Shiuan E, Meador CB, Roth M, Bordeaux J, Vaupel C, Boyd KL, Summitt IB, Wang LL, Schneider JT, Warner JL, Zhao Z, Lovly CM
(2019) J Thorac Oncol 14: 1970-1981
MeSH Terms: Aged, B7-H1 Antigen, Biomarkers, Tumor, Female, Humans, Lung Neoplasms, Lymphocytes, Tumor-Infiltrating, Male, Middle Aged, Paraneoplastic Syndromes, Nervous System, Prognosis, Retrospective Studies, Small Cell Lung Carcinoma, Survival Rate, Tumor Microenvironment
Added September 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Abatacept for Severe Immune Checkpoint Inhibitor-Associated Myocarditis.
Salem JE, Allenbach Y, Vozy A, Brechot N, Johnson DB, Moslehi JJ, Kerneis M
(2019) N Engl J Med 380: 2377-2379
MeSH Terms: Abatacept, Aged, Antineoplastic Agents, Immunological, Female, Humans, Immunosuppressive Agents, Lung Neoplasms, Myocarditis, Myositis, Nivolumab, Programmed Cell Death 1 Receptor
Added November 12, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data.
Rudin CM, Poirier JT, Byers LA, Dive C, Dowlati A, George J, Heymach JV, Johnson JE, Lehman JM, MacPherson D, Massion PP, Minna JD, Oliver TG, Quaranta V, Sage J, Thomas RK, Vakoc CR, Gazdar AF
(2019) Nat Rev Cancer 19: 289-297
MeSH Terms: Animals, Gene Expression Regulation, Neoplastic, Heterografts, Humans, Lung Neoplasms, Mice, Small Cell Lung Carcinoma, Transcription Factors, Transcription, Genetic
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
On-target Resistance to the Mutant-Selective EGFR Inhibitor Osimertinib Can Develop in an Allele-Specific Manner Dependent on the Original EGFR-Activating Mutation.
Brown BP, Zhang YK, Westover D, Yan Y, Qiao H, Huang V, Du Z, Smith JA, Ross JS, Miller VA, Ali S, Bazhenova L, Schrock AB, Meiler J, Lovly CM
(2019) Clin Cancer Res 25: 3341-3351
MeSH Terms: Acrylamides, Alleles, Aniline Compounds, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Dose-Response Relationship, Drug, Drug Resistance, Neoplasm, ErbB Receptors, Exons, Gene Expression Profiling, Humans, Lung Neoplasms, Models, Molecular, Mutation, Protein Binding, Protein Kinase Inhibitors, Structure-Activity Relationship
Added March 21, 2020
0 Communities
2 Members
0 Resources
17 MeSH Terms