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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 13

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Local injection of lovastatin in biodegradable polyurethane scaffolds enhances bone regeneration in a critical-sized segmental defect in rat femora.
Yoshii T, Hafeman AE, Esparza JM, Okawa A, Gutierrez G, Guelcher SA
(2014) J Tissue Eng Regen Med 8: 589-95
MeSH Terms: Animals, Biocompatible Materials, Bone Regeneration, Cell Line, Disease Models, Animal, Femur, Injections, Kinetics, Lovastatin, Mice, Microspheres, Polyurethanes, Rats, Tissue Scaffolds, X-Ray Microtomography
Added February 23, 2016
1 Communities
1 Members
0 Resources
15 MeSH Terms
Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I.
Wang W, Nyman JS, Ono K, Stevenson DA, Yang X, Elefteriou F
(2011) Hum Mol Genet 20: 3910-24
MeSH Terms: Animals, Bone Diseases, Developmental, Bone Remodeling, Bone and Bones, Chondrocytes, Collagen Type II, Enzyme Activation, Extracellular Signal-Regulated MAP Kinases, Female, Intervertebral Disc, Lovastatin, Mice, Mice, Knockout, Neurofibromatosis 1, Neurofibromin 1, Osteoblasts, Osteocytes, Osteogenesis, Phenotype, Porosity, Promoter Regions, Genetic, Recombination, Genetic, Stem Cells, ras Proteins
Added November 14, 2013
1 Communities
3 Members
0 Resources
24 MeSH Terms
A sustained release of lovastatin from biodegradable, elastomeric polyurethane scaffolds for enhanced bone regeneration.
Yoshii T, Hafeman AE, Nyman JS, Esparza JM, Shinomiya K, Spengler DM, Mundy GR, Gutierrez GE, Guelcher SA
(2010) Tissue Eng Part A 16: 2369-79
MeSH Terms: Animals, Biocompatible Materials, Bone Regeneration, Bone and Bones, Cell Differentiation, Delayed-Action Preparations, Elastomers, Kinetics, Lovastatin, Male, Mice, Microscopy, Electron, Scanning, Osteogenesis, Polyurethanes, Rats, Rats, Sprague-Dawley, Tissue Scaffolds
Added March 24, 2014
1 Communities
2 Members
0 Resources
17 MeSH Terms
Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.
Wang W, Nyman JS, Moss HE, Gutierrez G, Mundy GR, Yang X, Elefteriou F
(2010) J Bone Miner Res 25: 1658-67
MeSH Terms: Animals, Bone Density, Bony Callus, Fracture Healing, Lovastatin, Male, Mice, Neurofibromatosis 1, Neurofibromin 1, Osteoblasts, Tibial Fractures, X-Ray Microtomography
Added November 14, 2013
0 Communities
2 Members
0 Resources
12 MeSH Terms
Molecular beacons can assess changes in expression and 3'-polyadenylation of human eNOS mRNA.
Jones R, Baker MB, Weber M, Harrison DG, Bao G, Searles CD
(2009) Am J Physiol Cell Physiol 296: C498-504
MeSH Terms: Animals, Cells, Cultured, Endothelial Cells, Fluorescence Resonance Energy Transfer, Fluorescent Dyes, Gene Expression Regulation, Enzymologic, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Lovastatin, Lung, Mice, Nitric Oxide Synthase Type III, Nucleic Acid Hybridization, Oligonucleotide Probes, Physical Exertion, Polyadenylation, Polymerase Chain Reaction, RNA Interference, RNA, Messenger, Reproducibility of Results, Stress, Mechanical
Added December 10, 2013
1 Communities
1 Members
0 Resources
21 MeSH Terms
The sterol response element binding protein regulates cyclooxygenase-2 gene expression in endothelial cells.
Smith LH, Petrie MS, Morrow JD, Oates JA, Vaughan DE
(2005) J Lipid Res 46: 862-71
MeSH Terms: Animals, Base Sequence, CCAAT-Enhancer-Binding Proteins, Cattle, Cells, Cultured, Cyclooxygenase 2, DNA Primers, DNA-Binding Proteins, Endothelium, Vascular, Epoprostenol, Gene Expression Regulation, Enzymologic, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Lovastatin, Membrane Proteins, Promoter Regions, Genetic, Prostaglandin-Endoperoxide Synthases, Reverse Transcriptase Polymerase Chain Reaction, Sterol Regulatory Element Binding Protein 1, Sterol Regulatory Element Binding Protein 2, Transcription Factors
Added December 10, 2013
0 Communities
1 Members
0 Resources
21 MeSH Terms
A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.
Cooper MK, Wassif CA, Krakowiak PA, Taipale J, Gong R, Kelley RI, Porter FD, Beachy PA
(2003) Nat Genet 33: 508-13
MeSH Terms: 3T3 Cells, Animals, Anticholesteremic Agents, Cells, Cultured, Chick Embryo, Cholesterol, Cyclodextrins, Dose-Response Relationship, Drug, Hedgehog Proteins, Humans, Lovastatin, Mice, Models, Biological, Precipitin Tests, Receptors, Cell Surface, Receptors, G-Protein-Coupled, Signal Transduction, Smith-Lemli-Opitz Syndrome, Smoothened Receptor, Time Factors, Trans-Activators, Transfection
Added March 5, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Failure of antioxidant therapy to attenuate interstitial disease in rats with reversible nephrotic syndrome.
Drukker A, Eddy AA
(1998) J Am Soc Nephrol 9: 243-51
MeSH Terms: Animals, Anticholesteremic Agents, Antioxidants, Cholesterol, Collagen, Female, Fibronectins, Fibrosis, Kidney, Lipid Peroxides, Lipoproteins, LDL, Liver, Lovastatin, Macrophages, Microscopy, Fluorescence, Nephrotic Syndrome, Organ Size, Probucol, Proteinuria, Puromycin Aminonucleoside, Rats, Rats, Sprague-Dawley, Time Factors, Transforming Growth Factor beta, Treatment Failure, Vitamin E
Added February 3, 2012
0 Communities
1 Members
0 Resources
26 MeSH Terms
Lovastatin inhibits pancreatic cancer growth regardless of RAS mutation.
Sumi S, Beauchamp RD, Townsend CM, Pour PM, Ishizuka J, Thompson JC
(1994) Pancreas 9: 657-61
MeSH Terms: Animals, Base Sequence, Cell Division, Cricetinae, Genes, ras, Humans, Lovastatin, Molecular Sequence Data, Pancreatic Neoplasms, Point Mutation
Added May 3, 2013
0 Communities
1 Members
0 Resources
10 MeSH Terms
Effect of low-density lipoproteins, mevinolin, and G proteins on Ca2+ response in cultured chick atrial cells.
Tan W, Barnett JV, Pietrobon D, Hehn G, Greiser C, Marsh JD, Galper JB
(1993) Am J Physiol 265: H191-7
MeSH Terms: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester, Animals, Calcium, Calcium Channels, Cattle, Cells, Cultured, Chick Embryo, Dihydropyridines, Extracellular Space, Fetal Blood, GTP-Binding Proteins, Heart Atria, Lipoproteins, LDL, Lovastatin, Myocardium, Pertussis Toxin, Virulence Factors, Bordetella
Added February 21, 2016
0 Communities
1 Members
0 Resources
17 MeSH Terms